Analytic mode matching for a circular dissipative silencer containing mean flow and a perforated pipe

An analytic mode matching scheme that includes higher order modes is developed for a straight-through circular dissipative silencer. Uniform mean flow is added to the central airway and a concentric perforated screen separates the mean flow from a bulk reacting porous material. Transmission loss predictions are compared with experimental measurements and good agreement is demonstrated for three different silencers. Furthermore, it is demonstrated that, when mean flow is present, the axial kinematic matching condition should equate to that chosen for the radial kinematic boundary condition over the interface between the airway and the material. Accordingly, if the radial matching conditions are continuity of pressure and displacement, then the axial matching conditions should also be continuity of pressure and displacement, rather than pressure and velocity as previously thought. When a perforated screen is present the radial pressure condition changes, but the radial kinematic condition should always remain equivalent to that chosen for the axial kinematic matching condition; here, results indicate that continuity of displacement should be retained when a perforated screen is present

Sustainable Port Planning in Future Indonesian Ports: A Case Study of Mafa Port based on UN SDGs

As one of the biggest maritime nation in the world, Indonesia has big advantages and potential with its long coastline. Part of the maritime industry that Indonesia can provide is the port services. Port development hopes to carry the development of the area in many aspects with the sustainable approach. This study uses Mafa Port in Indonesia as the study case location. This study looks into the new port development effect in regard to 5 goals of United Nation Sustainable Development Goals (UN SDGs), to see the connection of new port to the regional development. As a result, this study identifies the related sustainable goals with the port development and also the approach being used by sustainable port base practices

A land-use transport-interaction framework for large scale strategic urban modeling

We introduce a family of land use transportation interaction (LUTI) models which enable future employment, population and flows or trips between these activities to be explained and predicted. We begin by focusing on the generic spatial interaction model, noting the ways in which its components reflect demand and supply at different locations measured in terms of employment and working population. This suggests an equilibrium structure which is our starting point in developing a simplified version of the model which we extend to deal with four different activity sectors – housing, retail activities, schools, and health facilities. We use this generic structure to develop four related versions of the generic LUTI model equations for residential populations, retailing, education and hospitals which are all driven by employment in terms of where people live and work. This constitutes our integrated framework that we use in calibrating, that is fine-tuning the model to three urban areas (cities) in Europe: to Oxford and its county, Turin and its region, and Athens in its hinterland of Attica reflecting population volumes from 700,000, 1.7 million and 3.8 million persons respectively. In each case, we use the models to predict the impact of different scenarios – new housing developments in Oxfordshire, new universities and metro lines in Turin, and economic development in the Athens region. We describe the details of these scenarios in Supplementary Information (SI) which shows the versatility of using the models to examine such impacts and we conclude with directions for improving the various models and nesting them at different scales within the land use-transport planning process

Numerical mode matching in dissipative silencers with temperature gradients and mean flow

This work presents a mathematical approach based on the mode matching method to compute the transmission loss of perforated dissipative silencers with temperature gradients and mean flow. Three-dimensional wave propagation is considered in silencer geometries with arbitrary, but axially uniform, cross section. To reduce the computational requirements of a full multidimensional finite element calculation, a method is developed combining axial and transversal solutions of the wave equation. First, the finite element method is employed in a twodimensional problem to extract the eigenvalues and associated eigenvectors for the silencer cross section. Mean flow as well as radial temperature gradients and the corresponding thermal-induced material heterogeneities are included in the model. Assuming a low acoustic influence of axial gradients (compared to radial variations), an axially uniform temperature field is taken into account, its value being the inlet/outlet average. A weighted residual approach is then used to match the acoustic fields (pressure and axial acoustic velocity) at the geometric discontinuities between the silencer chamber and the inlet and outlet pipes. Transmission loss predictions are compared favourably with a general three-dimensional finite element approach, offering a reduction in the computational effort

Gambaran Pengetahuan dan Sikap Pasien Tb Paru terhadap Upaya Pengendalian Tb di Puskesmas Sidomulyo Kota Pekanbaru

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which remains a global health threat. In Indonesia pulmonary TB is still a serious health problem with incidence rates are quite high. Pulmonary TB can be contained and prevented if people have knowledge and a good attitude so as to produce the appropriate control measures. The purpose of this study is to describe the knowledge and attitudes of TB patients in order to control efforts of TB in Puskesmas Sidomulyo Pekanbaru.The study was conducted in June 2016. This is a descriptive obeservational study with crosecctional approach. The instrument used was a questionnaire about knowledge, attitudes, and actions. The number of respondents is 31 patients of TB who were registered on the form of TB 06 in Puskesmas Sidomulyo Kota Pekanbaru and it has meet inclusion criteria of study. Results showed that sex characteristic of patients were predominantly male as many as 23 people (74,2%) and the most productive among patients aged 18-40 years as many as 20 people (64,5%). Characteristics by education level showed as many as 19 patients (61,3 %) was high school graduates and 90,3% had undergone treatment > 2 months. The result showed that respondents who have a quite good level of knowledge about tuberculosis as many as 12 people (38,7 %). Based on the attitudes showed that a positive attitude as many as 27 people (87%) and quite good level of actions as many as 4 people (13%)

Observational Constraints to the Evolution of Massive Stars

We consider some aspects of the evolution of massive stars which can only be elucidated by means of "indirect" observations, i.e. measurements of the effects of massive stars on their environments. We discuss in detail the early evolution of massive stars formed in high metallicity regions as inferred from studies of HII regions in external galaxies.Comment: 6 pages, 1 figure; Invited Paper presented at the Roma-Trieste Workshop 1999 "The Chemical Evolution of the Milky Way: Stars versus Clusters", Vulcano Island (ME, Italy), 20-24 September, 1999, eds. F. Giovannelli & F. Matteucci, Kluwer-Holland (in press

Intracellular trafficking and cellular uptake mechanism of PHBV nanoparticles for targeted delivery in epithelial cell lines

Indexación: Web of Science; Scopus; Scielo.Background: Nanotechnology is a science that involves imaging, measurement, modeling and a manipulation of matter at the nanometric scale. One application of this technology is drug delivery systems based on nanoparticles obtained from natural or synthetic sources. An example of these systems is synthetized from poly(3-hydroxybutyrate-co-3-hydroxyvalerate), which is a biodegradable, biocompatible and a low production cost polymer. The aim of this work was to investigate the uptake mechanism of PHBV nanoparticles in two different epithelial cell lines (HeLa and SKOV-3). Results: As a first step, we characterized size, shape and surface charge of nanoparticles using dynamic light scattering and transmission electron microscopy. Intracellular incorporation was evaluated through flow cytometry and fluorescence microscopy using intracellular markers. We concluded that cellular uptake mechanism is carried out in a time, concentration and energy dependent way. Our results showed that nanoparticle uptake displays a cell-specific pattern, since we have observed different colocalization in two different cell lines. In HeLa (Cervical cancer cells) this process may occur via classical endocytosis pathway and some internalization via caveolin-dependent was also observed, whereas in SKOV-3 (Ovarian cancer cells) these patterns were not observed. Rearrangement of actin filaments showed differential nanoparticle internalization patterns for HeLa and SKOV-3. Additionally, final fate of nanoparticles was also determined, showing that in both cell lines, nanoparticles ended up in lysosomes but at different times, where they are finally degraded, thereby releasing their contents. Conclusions: Our results, provide novel insight about PHBV nanoparticles internalization suggesting that for develop a proper drug delivery system is critical understand the uptake mechanism.https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-016-0241-

A multiscale study on the morphology and evolution of slip bands in a nickel-based superalloy during low cycle fatigue

Plastic deformation during low cycle fatigue in fcc materials with low stacking fault energy is accumulated in slip bands, which become preferential sites for crack initiation. Whilst these dislocation structures have been studied before, little has been done to assess the effect and evolution of the individual slip lines within them. In this study, samples of a γ′precipitate strengthened nickel-based superalloy are fatigued at room temperature and 700˚C for 1, 40 and 500 cycles.The resulting dislocation structures are characterised via Electron Channeling Contrast Imaging and Transmission Electron Microscopy. We introduce a new methodology to measure slip band parameters such as the slip line spacing and shear step length by analysing the holes left by sheared precipitates in γ′-etched secondary electron micrographs. Statistics of these parameters are obtained and compared for different conditions. Advantages of this technique include resolution at the scale of individual planes, acquisition of true three-dimensional data and applicability in the bulk of the material. The combination of these techniques provides a unique mechanistic and quantitative insight into the slip band and precipitate morphology evolution.Consejo Nacional de Ciencia y Tecnología Cambridge Commonwealth European and International Trust Roberto Rocca Education Program Royal Academy of Engineering Rolls-Royce plc Engineering and Physical Sciences Research Counci

Expression of Interest: The Atmospheric Neutrino Neutron Interaction Experiment (ANNIE)

Submitted for the January 2014 Fermilab Physics Advisory Committee meetingSubmitted for the January 2014 Fermilab Physics Advisory Committee meetingSubmitted for the January 2014 Fermilab Physics Advisory Committee meetingSubmitted for the January 2014 Fermilab Physics Advisory Committee meetingNeutron tagging in Gadolinium-doped water may play a significant role in reducing backgrounds from atmospheric neutrinos in next generation proton-decay searches using megaton-scale Water Cherenkov detectors. Similar techniques might also be useful in the detection of supernova neutrinos. Accurate determination of neutron tagging efficiencies will require a detailed understanding of the number of neutrons produced by neutrino interactions in water as a function of momentum transferred. We propose the Atmospheric Neutrino Neutron Interaction Experiment (ANNIE), designed to measure the neutron yield of atmospheric neutrino interactions in gadolinium-doped water. An innovative aspect of the ANNIE design is the use of precision timing to localize interaction vertices in the small fiducial volume of the detector. We propose to achieve this by using early production of LAPPDs (Large Area Picosecond Photodetectors). This experiment will be a first application of these devices demonstrating their feasibility for Water Cherenkov neutrino detectors