Effect of weathering product assemblages on Pb bioaccessibility in mine waste: implications for risk management

General assessments of orebody types and associated mine wastes with regards to their environmental signature and human health hazards are needed to help managing present and historical mine waste facilities. Bioaccessibility tests and mineralogical analysis were carried out on mine waste from a systematic sampling of mine sites from the Central Wales orefield, UK. The bioaccessible Pb widely ranged from 270 to 20300 mg/kg (mean 7250 mg/kg; median 4890 mg/kg) and the bioaccessible fraction from 4.53 % to >100 % (mean 33.2 %; median 32.2 %), with significant (p=0.001) differences among the mine sites. This implies sensitivity of bioaccessibility to site-specific conditions and suggests caution in the use of models to assess human health impacts generalised on the basis of the mineral deposit type. Mineralogical similarities of the oxidation products of primary galena provided a better control over the observed Pb bioaccessibility range. The higher Pb bioaccessibility (%) was related to samples containing cerussite, irrespective of the presence of other Pb minerals in the mineral assemblage; lower Pb bioaccessibility resulted where anglesite was the main Pb mineral phase and cerussite was absent. A solubility diagram for the various Pb minerals in the waste was derived using PHREEQC model and the experimental Pb concentration measured in the simulated gastric solution compared with the equilibrium modelling results. For samples containing cerussite, the model well predicted the soluble Pb concentrations measured in the experimental simulated gastric solution, indicative of the carbonate mineral phase control on the Pb in solution for these samples and little kinetic control on the dissolution of cerussite. On the contrary, most mine waste samples containing dominant anglesite and or plumbojarosite (no cerussite) had lower solution Pb values, falling at or below the anglesite and plumbojarosite solubility equilibrium concentrations, implying kinetic or textural factors hindering the dissolution

Mitochondrial Acetylation and Diseases of Aging

In recent years, protein lysine acetylation has emerged as a prominent and conserved regulatory posttranslational modification that is abundant on numerous enzymes involved in the processes of intermediary metabolism. Well-characterized mitochondrial processes of carbon utilization are enriched in acetyl-lysine modifications. Although seminal discoveries have been made in the basic biology of mitochondrial acetylation, an understanding of how acetylation states influence enzyme function and metabolic reprogramming during pathological states remains largely unknown. This paper will examine our current understanding of eukaryotic acetate metabolism and present recent findings in the field of mitochondrial acetylation biology. The implications of mitochondrial acetylation for the aging process will be discussed, as well as its potential implications for the unique and localized metabolic states that occur during the aging-associated conditions of heart failure and cancer growth

A Photometric and Spectroscopic Study of the Cataclysmic Variable SX Leonis Minoris in Quiescence and Superoutburst

We present CCD imaging, CCD photometry on long and short timescales, and time-resolved spectroscopy of SX LMi, a new SU Ursae Majoris type dwarf nova. The quiescent optical spectrum shows broad double-peaked Balmer, He I, and He II emission lines, similar to other quiescent dwarf novae. Absorption lines from a late-type secondary are not detected. Time-resolved spectra obtained in quiescence reveal radial velocity variations of the Balmer emission lines on a period of 0.06717 ± 0.00011 days, or 96.72 ± 0.16 minutes, with only a slight possibility of a daily cycle-count error. Optical photometry obtained between 1987 and 1991 shows flickering with a peak-to-peak amplitude of 0.18 mag. The binary orbital period can sometimes be seen in the photometric record. Long-term photometric monitoring by Indiana University\u27s robotic telescope RoboScope for a 3 year period between 1992 October and 1995 June shows seven well-defined outbursts and marginally detects a few others. The outburst interval varies between 34 and 64 days. During the 1994 December outburst, optical photometric observations show that SX LMi exhibited superhumps with a period of 0.06893 ± 0.00012 days, which is 2.6% ± 0.2% longer than the orbital period, as expected for a normal SU UMa star at this period. Spectra obtained during superoutburst show dramatic variations in the emission-line profiles on timescales of 10 minutes. Profile fits indicate that underlying absorption contributes to the shape of the Balmer emission-line profiles during superoutburst as in other dwarf novae in outburst or superoutburst. Direct images in good seeing show a ~19 mag companion star 195 from SX LMi

Nova Sagittarii 1994 #1 (V4332 Sagittarii): The Discovery and Evolution of an Unusual Luminous Red Variable Star

We report photometry and spectroscopy of the evolution of Nova Sagittarii 1994 #1 (V4332 Sagittarii) during outburst. We compare the photometric and spectral evolution of this outburst to known classes of outbursts -- including classical novae and outbursts occurring on symbiotic stars -- and find this object does NOT conform to any known class of outburst. The closest match to the behavior of this unusual object is M31 RV, an extremely luminous and red variable object discovered in the bulge of M31 in 1988. However, the temporal behavior and maximum luminosity of the two events differ by several orders of magnitude, requiring substantial intrinsic variation if these two events are members the same type of outburst. Our model of the spectroscopic evolution of this outburst shows that the effective temperature cooled from 4400 K to 2300 K over the three month span of our observations. In combination with line diagnostics in our later spectra, including [OI] lambda 5577 and the dramatic increase in the Halpha to Hbeta ratio, we infer the existence of a cool, dense (N_e ~ 10^{8-9} cm^{-3}) envelope that is optically thick in the Hydrogen Balmer recombination lines (case C). We suggest that a nuclear event in a single star, in which a slow shock drove the photosphere outwards, can power the observed luminosity evolution and the emission spectrum.Comment: Accepted for publication in AJ. 24 pages including 8 embedded postscript figures. Also available at http://www.astronomy.ohio-state.edu/~martini/pub

Infrared Photometric Variability of GX13+1 and GX17+2

We present infrared photometry of the Galactic Bulge X-ray binary systems GX13+1 and GX17+2 obtained in 1997 July and August using OSIRIS on the 1.8m Perkins Telescope at Lowell Observatory. GX13+1 clearly varies over ~0.6 magnitudes in the K-band. Our light curve suggests a modulation on a timescale of ~20 days, which is in agreement with previously proposed orbital periods for the system. The IR counterpart of GX17+2 is also variable in the K-band over \~0.8 magnitudes on a timescale of days to weeks, extending the variability first seen by Naylor, Charles, & Longmore (1991). We discuss the implications our data have for Deutsch et al's (1999) identification of ``star A'' as the true IR counterpart of GX17+2. The variability observed in our photometry of the blend of star A and the foreground star NP Ser implies a ~4 magnitude intrinsic variation in the K-band for GX17+2.Comment: Accepted for publication in ApJ, 5 pages, 4 figure

Mechanical properties of nanosheets and nanotubes investigated using a new geometry independent volume definition

Cross-sectional area and volume become difficult to define as material dimensions approach the atomic scale. This limits the transferability of macroscopic concepts such as Young's modulus. We propose a new volume definition where the enclosed nanosheet or nanotube average electron density matches that of the parent layered bulk material. We calculate the Young's moduli for various nanosheets (including graphene, BN and MoS2) and nanotubes. Further implications of this new volume definition such as a Fermi level dependent Young's modulus and out-of-plane Poisson's ratio are shown