607 research outputs found
The Lunar Dust Pendulum
Shadowed regions on the lunar surface acquire a negative potential. In particular, shadowed craters can have a negative potential with respect to the surrounding lunar regolith in sunlight, especially near the terminator regions. Here we analyze the motion of a positively charged lnnar dust grain in the presence of a shadowed crater at a negative potential in vacuum. Previous models describing the transport of charged lunar dust close to the surface have typically been limited to one-dimensional motion in the vertical direction, e.g. electrostatic levitation; however. the electric fields in the vicinity of shadowed craters will also have significant components in the horizontal directions. We propose a model that includes both the horizontal and vertical motion of charged dust grains near shadowed craters. We show that the dust grains execute oscillatory trajectories and present an expression for the period of oscillation drawing an analogy to the motion of a pendulum
PDB73 – Economic evaluation of blood glucose point–of–care testing in the intensive care unit
Gravitational waves from intermediate-mass-ratio inspirals for ground-based detectors
We explore the prospects for Advanced LIGO to detect gravitational waves from
neutron stars and stellar mass black holes spiraling into intermediate-mass
( to ) black holes. We estimate an event rate
for such \emph{intermediate-mass-ratio inspirals} (IMRIs) of up to --. Our numerical simulations show that if the central
body is not a black hole but its metric is stationary, axisymmetric, reflection
symmetric and asymptotically flat then the waves will likely be tri-periodic,
as for a black hole. We report generalizations of a theorem due to Ryan (1995)
which suggest that the evolutions of the waves' three fundamental frequencies
and of the complex amplitudes of their spectral components encode (in
principle) a full map of the central body's metric, full details of the energy
and angular momentum exchange between the central body and the orbit, and the
time-evolving orbital elements. We estimate that Advanced LIGO can measure or
constrain deviations of the central body from a Kerr black hole with modest but
interesting accuracy.Comment: Accepted for publication in Physical Review Letter
PSY57 Cost Effectiveness Analysis Evaluating Factor Viii As Primary Prophylaxis Treatment for Patients With Severe Haemophilia A In the Netherlands
Use of a Bayesian maximum-likelihood classifier to generate training data for brain–machine interfaces
Brain–machine interface decoding algorithms need to be predicated on assumptions that are easily met outside of an experimental setting to enable a practical clinical device. Given present technological limitations, there is a need for decoding algorithms which (a) are not dependent upon a large number of neurons for control, (b) are adaptable to alternative sources of neuronal input such as local field potentials (LFPs), and (c) require only marginal training data for daily calibrations. Moreover, practical algorithms must recognize when the user is not intending to generate a control output and eliminate poor training data. In this paper, we introduce and evaluate a Bayesian maximum-likelihood estimation strategy to address the issues of isolating quality training data and self-paced control. Six animal subjects demonstrate that a multiple state classification task, loosely based on the standard center-out task, can be accomplished with fewer than five engaged neurons while requiring less than ten trials for algorithm training. In addition, untrained animals quickly obtained accurate device control, utilizing LFPs as well as neurons in cingulate cortex, two non-traditional neural inputs.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90824/1/1741-2552_8_4_046009.pd
Poly(3,4-ethylenedioxythiophene) (PEDOT) polymer coatings facilitate smaller neural recording electrodes
We investigated using poly(3,4-ethylenedioxythiophene) (PEDOT) to lower the impedance of small, gold recording electrodes with initial impedances outside of the effective recording range. Smaller electrode sites enable more densely packed arrays, increasing the number of input and output channels to and from the brain. Moreover, smaller electrode sizes promote smaller probe designs; decreasing the dimensions of the implanted probe has been demonstrated to decrease the inherent immune response, a known contributor to the failure of long-term implants. As expected, chronically implanted control electrodes were unable to record well-isolated unit activity, primarily as a result of a dramatically increased noise floor. Conversely, electrodes coated with PEDOT consistently recorded high-quality neural activity, and exhibited a much lower noise floor than controls. These results demonstrate that PEDOT coatings enable electrode designs 15 µm in diameter.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90823/1/1741-2552_8_1_014001.pd
Post-Newtonian Approximation in Maxwell-Like Form
The equations of the linearized first post-Newtonian approximation to general
relativity are often written in "gravitoelectromagnetic" Maxwell-like form,
since that facilitates physical intuition. Damour, Soffel and Xu (DSX) (as a
side issue in their complex but elegant papers on relativistic celestial
mechanics) have expressed the first post-Newtonian approximation, including all
nonlinearities, in Maxwell-like form. This paper summarizes that DSX
Maxwell-like formalism (which is not easily extracted from their celestial
mechanics papers), and then extends it to include the post-Newtonian
(Landau-Lifshitz-based) gravitational momentum density, momentum flux (i.e.
gravitational stress tensor) and law of momentum conservation in Maxwell-like
form. The authors and their colleagues have found these Maxwell-like momentum
tools useful for developing physical intuition into numerical-relativity
simulations of compact binaries with spin.Comment: v4: Revised for resubmission to Phys Rev D, 6 pages. v3: Reformulated
in terms of DSX papers. Submitted to Phys Rev D, 6 pages. v2: Added
references. Changed definitions & convention
Managing juvenile idiopathic arthritis within the context of their life:What we learnt from children and youth living with juvenile idiopathic arthritis and their parents
Introduction: Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children and causes short- and long-term disability. Optimal management requires pharmacologic and non-pharmacologic interventions. Few studies have explored the youth and family experience of the management of JIA. This study's objective was to explore the management experience of youth with JIA and their parents. Methods: This qualitative study used semi-structured interviews with youth 12–18 years of age with JIA receiving biological medication and parents of children with JIA on biological medication. Participants were recruited in clinics using convenience sampling. A thematic analysis approach was employed for data analysis. Results: Nine youth and 14 parents participated. Four themes were identified that encompassed an overarching theme of participants managing JIA within the context of their life: aspects of life affected by JIA and its management, lived experience with JIA management, medication decision-making, and involvement in decision-making. Juvenile idiopathic arthritis management is situated within the context of their life but is normally (outside acute events) not central. Conclusion: Two dimensions were added to those in the literature: parents' overall approaches to health and the sense of urgency surrounding decision-making. Our findings reinforce the importance of person- and family-centred care in paediatric rheumatology. That is, identifying what matters most to youth and their parents given their current life circumstances to provide a foundation for discussions of how they want to manage their JIA.</p
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