974 research outputs found

    Comment on "Far-field microscopy with a nanometer-scale resolution based on the in-plane image magnification by surface plasmon polaritons"

    Full text link
    This is a small comment concerning the work by Smolyaninov et al. in Phys. Rev. Lett.94, 057401 (2005)

    Analytical and experimental stability investigation of a hardware-in-the-loop satellite docking simulator

    Full text link
    The European Proximity Operation Simulator (EPOS) of the DLR-German Aerospace Center is a robotics-based simulator that aims at validating and verifying a satellite docking phase. The generic concept features a robotics tracking system working in closed loop with a force/torque feedback signal. Inherent delays in the tracking system combined with typical high stiffness at contact challenge the stability of the closed-loop system. The proposed concept of operations is hybrid: the feedback signal is a superposition of a measured value and of a virtual value that can be tuned in order to guarantee a desired behavior. This paper is concerned with an analytical study of the system's closed-loop stability, and with an experimental validation of the hybrid concept of operations in one dimension (1D). The robotics simulator is modeled as a second-order loop-delay system and closed-form expressions for the critical delay and associated frequency are derived as a function of the satellites' mass and the contact dynamics stiffness and damping parameters. A numerical illustration sheds light on the impact of the parameters on the stability regions. A first-order Pade approximation provides additional means of stability investigation. Experiments were performed and tests results are described for varying values of the mass and the damping coefficients. The empirical determination of instability is based on the coefficient of restitution and on the observed energy. There is a very good agreement between the critical damping values predicted by the analysis and observed during the tests...Comment: 16 page

    Plasmonic crystal demultiplexer and multiports

    Full text link
    Artificially built periodic optical structures in dielectric and metallic media have generated considerable interest due to their potential for optical device miniaturization. In this context plasmonics, i.e., optics based on surface plasmon polaritons (SPPs) offers new exciting prospects. SPPs are hybrid light/electron surface waves at the interface between a dielectric and a metal and as such hold the potential for 2D optical functionality. Indeed, SPP elements as mirrors, splitters and interferometers have been recently demonstrated. However, for plasmonics to qualify at the information technology level requires necessarily the realization of wavelength division (demultiplexing) which constitutes a fundamental ingredient of optical communication. In the following we experimentally demonstrate 2D SPP demultiplexing in the visible spectral range by using photonic crystals for SPPs (plasmonic crystals). In addition, we demonstrate that plasmonic crystal are capable of realizing integrated linear multiports which could constitute building blocks of analog or quantum optical computing.Comment: Nano Lett.7, 1697 (2007

    Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches.

    Get PDF
    Kindlin-3 (K3)-mediated integrin adhesion controls homing and bone marrow (BM) retention of normal hematopoietic cells. However, the role of K3 in leukemic stem cell (LSC) retention and growth in the remodeled tumor-promoting BM is unclear. We report that loss of K3 in a mouse model of chronic myeloid leukemia (CML) triggers the release of LSCs from the BM into the circulation and impairs their retention, proliferation, and survival in secondary organs, which curbs CML development, progression, and metastatic dissemination. We found de novo expression of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) on CML-LSCs but not normal hematopoietic stem cells and this enabled us to specifically deplete K3 with a CTLA-4-binding RNA aptamer linked to a K3-siRNA (small interfering RNA) in CTLA-4+ LSCs in vivo, which mobilized LSCs in the BM, induced disease remission, and prolonged survival of mice with CML. Thus, disrupting interactions of LSCs with the BM environment is a promising strategy to halt the disease-inducing and relapse potential of LSCs

    Introduction to the issue on surface plasmon photonics

    Get PDF
    [No abstract
    • …
    corecore