Statistical isotropy of the Cosmic Microwave Background

The breakdown of statistical homogeneity and isotropy of cosmic perturbations is a generic feature of ultra large scale structure of the cosmos, in particular, of non trivial cosmic topology. The statistical isotropy (SI) of the Cosmic Microwave Background temperature fluctuations (CMB anisotropy) is sensitive to this breakdown on the largest scales comparable to, and even beyond the cosmic horizon. We propose a set of measures, $\kappa_\ell$ ($\ell=1,2,3, ...$) which for non-zero values indicate and quantify statistical isotropy violations in a CMB map. We numerically compute the predicted $\kappa_\ell$ spectra for CMB anisotropy in flat torus universe models. Characteristic signature of different models in the $\kappa_\ell$ spectrum are noted.Comment: Presented at PASCOS'03, January 3-8, 2003, in TIFR, Mumbai; to be published in a special issue of 'Pramana' (4 pages, 1 figure, style files included

Interaction of Anticancer Drug Methotrexate with DS-DNA Analyzed by Spectroscopic and Electrochemical Methods

Abstract: Cyclic voltammetry coupled with UV/Vis spectroscopic techniques were used to study the interaction of methotrexate (MTX), an antitumor drug, with double stranded fish sperm DNA (ds-DNA) in phosphate buffer solution (pH 7.4). The interaction of MTX with DNA could result a considerable decrease in the MTX peak current. The variations in the spectroscopy and electrochemical characteristics of MTX indicated MTX bind to DNA by a groove binding mode. This conclusion was reinforced by viscosity data. The apparent transfer coefficients (α) and the number of electron transferred (n) of methotrexate in the absence and preset of ds-DNA have determined using anodic Tafel plots of MTX and MTX-DNA adduct on the surface of glassy carbone electrode. The diffusion coefficients of MTX in the absence (D 0 ) f and presence (D 0 ) b of DNA were calculated as 7.30×10 -6 and 3.40×10 -6 Cm 2 s -1 respectively. In spectrophotometric studies, the slopes of the calibration curves for methotrexate in the absence and presence of ds-DNA differ significantly. These studies are valuable for a better understanding the detailed mode of MTX-DNA interaction, which should be important in deeper insight into the therapeutic efficacy of MTX and design of new DNA targeted drug

Stellar Astrophysics with a Dispersed Fourier Transform Spectrograph. II. Orbits of Double-lined Spectroscopic Binaries

We present orbital parameters for six double-lined spectroscopic binaries (iota Pegasi, omega Draconis, 12 Bootis, V1143 Cygni, beta Aurigae, and Mizar A) and two double-lined triple star systems (kappa Pegasi and eta Virginis). The orbital fits are based upon high-precision radial velocity observations made with a dispersed Fourier Transform Spectrograph, or dFTS, a new instrument which combines interferometric and dispersive elements. For some of the double-lined binaries with known inclination angles, the quality of our RV data permits us to determine the masses M_1 and M_2 of the stellar components with relative errors as small as 0.2%.Comment: 41 pages, 8 figures, accepted by A

Observational Study of the Multistructured Planetary Nebula NGC 7354

We present an observational study of the planetary nebula (PN) NGC 7354 consisting of narrowband Halpha and [NII]6584 imaging as well as low- and high-dispersion long-slit spectroscopy and VLA-D radio continuum. According to our imaging and spectroscopic data, NGC 7354 has four main structures: a quite round outer shell and an elliptical inner shell, a collection of low-excitation bright knots roughly concentrated on the equatorial region of the nebula, and two symmetrical jet-like features, not aligned either with the shells' axes, or with each other. We have obtained physical parameters like electron temperature and electron density as well as ionic and elemental abundances for these different structures. Electron temperature and electron density slightly vary throughout the nebula. The local extinction coefficient c_Hbeta shows an increasing gradient from south to north and a decreasing gradient from east to west consistent with the number of equatorial bright knots present in each direction. Abundance values show slight internal variations but most of them are within the estimated uncertainties. In general, abundance values are in good agreement with the ones expected for PNe. Radio continuum data are consistent with optically thin thermal emission. We have used the interactive three-dimensional modeling tool SHAPE to reproduce the observed morphokinematic structures in NGC 7354 with different geometrical components. Our SHAPE model is in very good agreement with our imaging and spectroscopic observations. Finally, after modeling NGC 7354 with SHAPE, we suggest a possible scenario for the formation of the nebula.Comment: Accepted for publication in AJ, 12 pages, 8 figure

Cosmological Imprints of Pre-Inflationary Particles

We study some of the cosmological imprints of pre-inflationary particles. We show that each such particle provides a seed for a spherically symmetric cosmic defect. The profile of this cosmic defect is fixed and its magnitude is linear in a single parameter that is determined by the mass of the pre-inflationary particle. We study the CMB and peculiar velocity imprints of this cosmic defect and suggest that it could explain some of the large scale cosmological anomalies.Comment: 31 pages, 7 figure

`Standard' Cosmological model & beyond with CMB

Observational Cosmology has indeed made very rapid progress in the past decade. The ability to quantify the universe has largely improved due to observational constraints coming from structure formation Measurements of CMB anisotropy and, more recently, polarization have played a very important role. Besides precise determination of various parameters of the `standard' cosmological model, observations have also established some important basic tenets that underlie models of cosmology and structure formation in the universe -- `acausally' correlated initial perturbations in a flat, statistically isotropic universe, adiabatic nature of primordial density perturbations. These are consistent with the expectation of the paradigm of inflation and the generic prediction of the simplest realization of inflationary scenario in the early universe. Further, gravitational instability is the established mechanism for structure formation from these initial perturbations. The signature of primordial perturbations observed as the CMB anisotropy and polarization is the most compelling evidence for new, possibly fundamental, physics in the early universe. The community is now looking beyond the estimation of parameters of a working `standard' model of cosmology for subtle, characteristic signatures from early universe physics.Comment: 16 pages, 6 figures, Plenary talk, Proc. of GR-19, Mexico City, Mexico (Jul 5-9, 2010). To appear in a special issue in Class. Q. Gra

Correlations in the (Sub)Mil1imeter Background from ACT x BLAST

We present measurements of the auto- and cross-frequency correlation power spectra of the cosmic (sub)millimeter background at: 250, 350, and 500 microns (1200, 860, and 600 GHz) from observations made with the Balloon-borne Large Aperture Submillimeter Telescope, BLAST; and at 1380 and 2030 microns (218 and 148 GHz) from observations made with the Atacama Cosmology Telescope, ACT. The overlapping observations cover 8.6 deg(sup 2) in an area relatively free of Galactic dust near the south ecliptic pole (SEP). The ACT bands are sensitive to radiation from the CMB, the Sunyaev-Zel'dovich (SZ) effect from galaxy clusters, and to emission by radio and dusty star-forming galaxies (DSFGs), while the dominant contribution to the BLAST bands is from DSFGs. We confirm and extend the BLAST analysis of clustering with an independent pipeline, and also detect correlations between the ACT and BLAST maps at over 25(sigma) significance, which we interpret as a detection of the DSFGs in the ACT maps. In addition to a Poisson component in the cross-frequency power spectra, we detect a clustered signal at 4(sigma), and using a model for the DSFG evolution and number counts, we successfully fit all our spectra with a linear clustering model and a bias that depends only on red shift and not on scale. Finally, the data are compared to, and generally agree with, phenomenological models for the DSFG population. This study represents a first of its kind, and demonstrates the constraining power of the cross-frequency correlation technique to constrain models for the DSFGs. Similar analyses with more data will impose tight constraints 011 future models