ECCO: Edge-cloud chaining and orchestration framework for road context assessment

© 2020 IEEE. For road safety, detecting and reacting efficiently to road hazards is crucial and yet challenging due to practical restrictions such as limited data availability, which relies on network support. Moreover, from a system perspective we lack a computational model capable of providing to vehicles reliable and real-time assessment of the road context. As autonomous vehicles become widespread, the safety issues are further aggravated by the gap between cloud, roadside infrastructure and road users in terms of communication latency, software-hardware compatibility and data interoperability. To tackle this, we present ECCO: an orchestration framework that enables edge-cloud collaborative computing for road context assessment. ECCO can create on-demand task execution pipelines spanning multiple, potentially resource-constrained edge-nodes with the smart IoT infrastructure support. Our prototype lays the groundwork to support new services, which can use more efficiently the road infrastructure and deliver safety-critical applications for road users

The Role of Lichens, Mosses, and Vascular Plants in the Biodeterioration of Historic Buildings: A Review

Biodeterioration is defined as the alteration of a given substrate due to a combination of physical and chemical factors produced by living organisms when attached to such materials. This phenomenon attracts scientific research attention due to its risk in causing destruction to outdoor cultural rock heritage sites. In this review, an update on the state-of-art regarding the biodeterioration phenomenon is represented in order to highlight the type of colonizing vegetation and possible mechanisms behind the corresponding deterioration. For this reason, 62 articles with a focus on lichens, mosses, and higher plants were investigated by evaluating the role of construction materials and different plant species related to the hazard index. The results showed that trees and shrubs are the most harmful plant life forms, for example, Ficus carica, Ailanthus altissima, and Capparis spinosa, while regarding building materials, those characterized by high porosity, such as andesite and argillaceous limestone, are more vulnerable to plant colonization. Further studies are needed to examine in detail the relationship between colonizing organisms, intrinsic elements of the substrate, and external factors, as well as the refinement of measures to prevent and control colonization by plants

Base de dados climáticos.

Um repositório organizado de dados é uma exigência em qualquer empresa, como componente de eficiência, e a forma adequada para isto é utilizar uma ferramenta de banco de dados. Focando a pesquisa agropecuária, que necessita de dados climáticos como um dos componentes do ambiente que condicionam a produção, ter esses dados atualizados e disponíveis para acesso é uma necessidade para a empresa. A primeira ferramenta de banco de dados surgiu na IBM como forma de reduzir trabalho e custo no armazenamento e organização de dados, e o modelo relacional de banco de dados, utilizado neste documento, surgiu na década de 70, e até hoje é um dos mais utilizados, com a Linguagem Estruturada de Consulta – SQL, desenvolvida na década de 80, e adotada universalmente. Desta forma, o produto apresentado nesta publicação é uma forma de permitir o acesso aos usuários a toda base climática disponível na Unidade até 2011, ao mesmo tempo popularizando um sistema de banco de dados para o grupamento de pesquisa, por meio de um passo a passo.bitstream/item/70054/1/doc-141.pd

In situ polymerization of soil organic matter by oxidative biomimetic catalysis.

Background: Agricultural practices that enhance organic matter content in soil can play a central role in sequestering soil organic carbon (SOC) and reducing greenhouse gases emissions. Methods: We used a water-soluble iron-porphyrin to catalyze directly in situ oxidative polymerization of soil organic matter in the presence of H2O2 oxidant, with the aim to enhance OC stabilization, and, consequently, reduce CO2 emissions from soil. The occurred SOC stabilization was assessed by monitoring soil aggregate stability, OC distribution in water-soluble aggregates, soil respiration, and extraction yields of humic and fulvic acids. Results: Soil treatment with H2O2 and iron-porphyrin increased the physical stability of water-stable soil aggregates and the total OC content in small aggregates, thereby suggesting that the catalyzed oxidative polymerization increased OC in soil and induced a soil physical improvement. The significant reduction of CO2 respired by the catalyst- and H2O2-treated soil indicated an enhanced resistance of polymerized SOC to microbial mineralization. The catalyzed oxidative polymerization of SOC also significantly decreased the extraction yields of humic and fulvic acids from soil. Conclusions: The oxidative catalytic technology described here may become an efficient agricultural practice for OC sequestration in soils and contribute to mitigate global changes

Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44.

Sulfatase modifying factor 1 (SUMF1) encodes for the formylglicine generating enzyme, which activates sulfatases by modifying a key cysteine residue within their catalytic domains. SUMF1 is mutated in patients affected by multiple sulfatase deficiency, a rare recessive disorder in which all sulfatase activities are impaired. Despite the absence of canonical retention/retrieval signals, SUMF1 is largely retained in the endoplasmic reticulum (ER), where it exerts its enzymatic activity on nascent sulfatases. Part of SUMF1 is secreted and paracrinally taken up by distant cells. Here we show that SUMF1 interacts with protein disulfide isomerase (PDI) and ERp44, two thioredoxin family members residing in the early secretory pathway, and with ERGIC-53, a lectin that shuttles between the ER and the Golgi. Functional assays reveal that these interactions are crucial for controlling SUMF1 traffic and function. PDI couples SUMF1 retention and activation in the ER. ERGIC-53 and ERp44 act downstream, favoring SUMF1 export from and retrieval to the ER, respectively. Silencing ERGIC-53 causes proteasomal degradation of SUMF1, while down-regulating ERp44 promotes its secretion. When over-expressed, each of three interactors favors intracellular accumulation. Our results reveal a multistep control of SUMF1 trafficking, with sequential interactions dynamically determining ER localization, activity and secretion

A performance prediction model for pumps as turbines (PATs)

In recent years, the interest towards the use of pumps operating as turbines (PATs) for the generation of electrical energy has increased, due to the low cost of implementation and maintenance. The main issue that inhibits a wider use of PATs is the lack of corresponding characteristic curves, because manufacturers usually provide only the pump-mode performance characteristics. In the PAT selection phase, the lack of turbine-mode characteristic curves forces users to expend expensive and time-consuming efforts in laboratory testing. In the technical literature, numerous methods are available for the prediction of PAT turbine-mode performance based on the pump-mode characteristics, but these models are usually calibrated making use of few devices. To overcome this limit, a performance database called Redawn is presented and the data collected are used to calibrate novel PAT performance models

The Evaluation of a Mind–Body Intervention (MBT-T) for Stress Reduction in Academic Settings: A Pilot Study

This study is aimed at evaluating the outcomes of mind–body transformation therapy (MBT-T), previously known as the creative psychosocial genomic healing experience© (CPGHE). The intervention was aimed at reducing the perceived level of stress in two non-clinical groups of students with dierent educational levels and dierent expertise in the domain of well-being. Whereas participants from the first group were first-year university students, participants from the second group were students attending a post-graduate program in psychotherapy. All participants (n = 159) were exposed to a single session of MBT-T, each group in a separate session. The results of two paired-samples t-tests, conducted separately on the two samples, showed that there was a statistically significant reduction in the participants’ perceived level of stress between pre- and post-intervention states in both samples (t88 = 5.39, p < 0.001; t53 = 4.56, p < 0.001 respectively). The results, therefore, showed that a single session of MBT-T was beneficial in reducing the perceived level of stress in both first-year university students and students attending a post-graduate program in psychotherapy, regardless of educational level and expertise in the domain of well-being

Climatic and anthropogenic factors affect Ailanthus altissima invasion in a Mediterranean region

Ailanthus altissima is an aggressive invasive tree worldwide, but the ecological factors that lead to the spread of this species in Mediterranean ecosystems are still unclear. Here we aim to identify such factors, focusing on the interaction of human activity with climatic conditions. We determined the occurrence and abundance of Ailanthus in 240 sites and studied their relationship with 20 variables representing climatic, geographic, and topographic factors, as well as land use, in the region of Campania (southern Italy). Overall, we found that temperature and rainfall in Campania are suitable for Ailanthus, with the only major constraint being the temperature at an altitude exceeding 900 m a.s.l. We found that Ailanthus is unable to spread where the mean annual temperature is lower than 11.1 °C. By contrast, precipitation variables showed poor correlation with Ailanthus distribution, suggesting that rainfall in the selected study sites is suitable to sustain the growth of this tree. About land use variables, roads were the primary landscape feature along which this species spread and invaded new areas. Roads probably combine high propagule pressure and favorable growing conditions in terms of available resources i.e., light, water, and mineral nutrients, that allow Ailanthus to establish and spread along roadside edges in different ecosystems. In conclusion, we found that climate and human-associated variables are correlated with the current occurrence of Ailanthus, with the temperature being more influential at high elevation sites and road distance playing a prominent role in low elevation areas

Biological properties of a human compact anti-ErbB2 antibody.

ErbB2 is a prognostic factor and target of therapy for many carcinomas. In contrast with the other ErbB receptors, ErbB2 lacks a soluble direct ligand, but it is the preferred co-receptor for the ErbB family members, forming heterodimers with more potent and prolonged signalling activity than that of homodimers. We recently produced a new anti-ErbB2 antibody, Erb-hcAb, by fusion of Erbicin, a human, anti-ErbB2 scFv, selectively cytotoxic to ErbB2-positive cells, and a human Fc domain. This fully human antitumour antibody represents a compact version of an IgG1, with the cytotoxicity of the scFv moiety on target cells, combined with the ability of the Fc moiety to induce both antibody- and complement-dependent cytotoxicity. Here, we describe the main properties of Erb-hcAb, using as a reference Herceptin, an anti-ErbB2 humanized monoclonal currently employed in clinical immunotherapy. We found that both bivalent Erb-hcAb and Herceptin increase receptor phosphorylation and downregulation, whereas monovalent Erbicin does not. These results correlate with the finding that Erb-hcAb is capable of inducing apoptosis and inhibiting cell cycle progression in ErbB2-positive cells. Its powerful in vitro antitumour action matched that observed in vivo in experiments with human ErbB2-positive tumour xenografts established in athymic mice. Finally, Erb-hcAb displays a glycosylation profile virtually superimposable to that of a human IgG. These findings suggest that Erb-hcAb is a very promising new agent for the immunotherapy of carcinomas that overexpress the ErbB2 receptor