3,994 research outputs found
Aircraft cockpit vision: Math model
A mathematical model was developed to describe the field of vision of a pilot seated in an aircraft. Given the position and orientation of the aircraft, along with the geometrical configuration of its windows, and the location of an object, the model determines whether the object would be within the pilot's external vision envelope provided by the aircraft's windows. The computer program using this model was implemented and is described
Landau-Khalatnikov-Fradkin Transformations and the Fermion Propagator in Quantum Electrodynamics
We study the gauge covariance of the massive fermion propagator in three as
well as four dimensional Quantum Electrodynamics (QED). Starting from its value
at the lowest order in perturbation theory, we evaluate a non-perturbative
expression for it by means of its Landau-Khalatnikov-Fradkin (LKF)
transformation. We compare the perturbative expansion of our findings with the
known one loop results and observe perfect agreement upto a gauge parameter
independent term, a difference permitted by the structure of the LKF
transformations.Comment: 9 pages, no figures, uses revte
Impact of Tandem Repeats on the Scaling of Nucleotide Sequences
Techniques such as detrended fluctuation analysis (DFA) and its extensions
have been widely used to determine the nature of scaling in nucleotide
sequences. In this brief communication we show that tandem repeats which are
ubiquitous in nucleotide sequences can prevent reliable estimation of possible
long-range correlations. Therefore, it is important to investigate the presence
of tandem repeats prior to scaling exponent estimation.Comment: 14 Pages, 3 Figure
Gauge Dependence of Mass and Condensate in Chirally Asymmetric Phase of Quenched QED3
We study three dimensional quenched Quantum Electrodynamics in the bare
vertex approximation. We investigate the gauge dependence of the dynamically
generated Euclidean mass of the fermion and the chiral condensate for a wide
range of values of the covariant gauge parameter . We find that (i) away
from , gauge dependence of the said quantities is considerably reduced
without resorting to sophisticated vertex {\em ansatze}, (ii) wavefunction
renormalization plays an important role in restoring gauge invariance and (iii)
the Ward-Green-Takahashi identity seems to increase the gauge dependence when
used in conjunction with some simplifying assumptions. In the Landau gauge, we
also verify that our results are in agreement with those based upon dimensional
regularization scheme within the numerical accuracy available.Comment: 14 pages, 11 figures, uses revte
Requirement Model For Mobile Bus Rental And Reservation Application
The main objectives of this study are to design a bus rental and reservation system for searching the availability of bus, the price of bus rental, and reserve the bus, to develop a system of the Bus Rental and Reservation System. The design is tested on the prototype
and evaluated to test the usability and acceptability of the system. The Wireless Application Protocol (WAP) technologies have been used in this application has enable
users to make booking through mobile telephones
PHARMACOGENETIC VARIATIONS RELATED TO CLOPIDOGREL RESISTANCE AND ITS CLINICAL IMPLICATIONS: AN ISSUE WHICH REMAINS LARGELY UNADDRESSED
Objectives: Antiplatelet therapy with either clopidogrel alone or in combination with aspirin is the mainstay prophylactic drug therapy followingpercutaneous coronary intervention and long-term prevention of cardiovascular and cerebrovascular events. Non-responders/semi-responders to clopidogrel are reported to have increased incidences of adverse outcomes like recurrent ischemic attacks. Variability in response to clopidogrel ismore common among Asians, and it is as high as 70% in some of the Asian communities. Researchers attribute inter-individual variations in responseto clopidogrel to various pharmacogenetic determinants. Polymorphisms of multidrug resistance protein 1, CYP2C19 and its alleles, P2Y adenosine diphosphate (ADP) receptor are concluded to be specific to clopidogrel resistance in Indian population.Methods: A thorough literature search was done use different keywords such as clopidogrel resistance, pharmacogenomics, pharmacogeneticvariability, and ethnic variability from database sources such as Google Scholar, Medline, PubMed Central, and Scopus.Results and Conclusion: Literature revealed a disparity between various pharmacogenetic determinants of clopidogrel resistance, particularly inthe Asian population. Few studies suggest that there is no significant association between clopidogrel response variability and ADP receptor P2Yand P2Y gene polymorphisms. Variation in the cytochrome P450 2C19 (CYP2C19) gene coding for the CYP2C19 enzyme, involved in metabolism and conversion of the clopidogrel to active metabolites is considered one of the major determinants of clopidogrel resistance in some populations. Pooled data from various studies suggest that variability in clopidogrel response cannot be attributed to a single gene polymorphism and is thought to be multifactorial. However, disparity in the data related to the specific gene polymorphisms responsible for the encountered clopidogrel resistance necessitates the further evaluation of genome. 12Keywords: Clopidogrel, Clopidogrel resistance, Single gene polymorphisms, Inter-individual variability. 1 , and P2Y 12
CRITICAL REVIEW OF PHARMACOGENOMICS IN ANTIPARKINSONIAN DRUG THERAPY: IMPACT ON CLINICAL MANAGEMENT OF PARKINSON'S DISEASE
Parkinson's disease is a progressive neurodegenerative disorder characterized by rest tremors, bradykinesia , rigidity , postural instability , gait dysfunction and several non motor symptoms . The marked difference in drug response and adverse effect profile among patients led to search of genetic markers and polymorphism associated with response to antiparkinsonian drugs which will enable us to predict an individuals  response to drugs in terms of both efficacy and toxicity. Hence efforts to define the role of genetic polymorphism in optimizing pharmacotherapy of Parkinson's disease have been undertaken and some promising genetic loci for the treatment have been determined. Therefore we aim to present a critical review of pharmacogenetic aspects of levodopa , dopamine agonists and COMT inhibitors and describe gene polymorphism of interest for future research.Â
Resource Aware Sensor Nodes in Wireless Sensor Networks
Wireless sensor networks are continuing to receive considerable research interest due, in part, to the range of possible applications. One of the greatest challenges facing researchers is in overcoming the limited network lifetime inherent in the small locally powered sensor nodes. In this paper, we propose IDEALS, a system to manage a wireless sensor network using a combination of information management, energy harvesting and energy monitoring, which we label resource awareness. Through this, IDEALS is able to extend the network lifetime for important messages, by controlling the degradation of the network to maximise information throughput
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