Correlated Cascades: Compete or Cooperate

In real world social networks, there are multiple cascades which are rarely independent. They usually compete or cooperate with each other. Motivated by the reinforcement theory in sociology we leverage the fact that adoption of a user to any behavior is modeled by the aggregation of behaviors of its neighbors. We use a multidimensional marked Hawkes process to model users product adoption and consequently spread of cascades in social networks. The resulting inference problem is proved to be convex and is solved in parallel by using the barrier method. The advantage of the proposed model is twofold; it models correlated cascades and also learns the latent diffusion network. Experimental results on synthetic and two real datasets gathered from Twitter, URL shortening and music streaming services, illustrate the superior performance of the proposed model over the alternatives

Recurrent Poisson Factorization for Temporal Recommendation

Poisson factorization is a probabilistic model of users and items for recommendation systems, where the so-called implicit consumer data is modeled by a factorized Poisson distribution. There are many variants of Poisson factorization methods who show state-of-the-art performance on real-world recommendation tasks. However, most of them do not explicitly take into account the temporal behavior and the recurrent activities of users which is essential to recommend the right item to the right user at the right time. In this paper, we introduce Recurrent Poisson Factorization (RPF) framework that generalizes the classical PF methods by utilizing a Poisson process for modeling the implicit feedback. RPF treats time as a natural constituent of the model and brings to the table a rich family of time-sensitive factorization models. To elaborate, we instantiate several variants of RPF who are capable of handling dynamic user preferences and item specification (DRPF), modeling the social-aspect of product adoption (SRPF), and capturing the consumption heterogeneity among users and items (HRPF). We also develop a variational algorithm for approximate posterior inference that scales up to massive data sets. Furthermore, we demonstrate RPF's superior performance over many state-of-the-art methods on synthetic dataset, and large scale real-world datasets on music streaming logs, and user-item interactions in M-Commerce platforms.Comment: Submitted to KDD 2017 | Halifax, Nova Scotia - Canada - sigkdd, Codes are available at https://github.com/AHosseini/RP

Trends in Elasticity and Electronic Structure of Transition-Metal Nitrides and Carbides from First Principles

The elastic properties of the $B_1$-structured transition-metal nitrides and their carbide counterparts are studied using the {\it ab initio\} density functional perturbation theory. The linear response results of elastic constants are in excellent agreement with those obtained from numerical derivative methods, and are also consistent with measured data. We find the following trends: (1) Bulk moduli $B$ and tetragonal shear moduli $G^{\prime}=(C_{11}-C_{12})/2$, increase and lattice constants $a_{0}$ decrease rightward or downward on the Periodic Table for the metal component or if C is replaced by N; (2) The inequality $B > G^{\prime} > G > 0$ holds for $G=C_{44}$; (3) $G$ depends strongly on the number of valence electrons per unit cell ($Z_{V}$). From the fitted curve of $G$ as a function of $Z_{V}$, we can predict that MoN is unstable in $B_{1}$ structure, and transition-metal carbonitrides ($e.g.$ ZrC$_{x}$N$_{1-x}$) and di-transition-metal carbides ($e.g.$ Hf$_{x}$Ta$_{1-x}$C) have maximum $G$ at $Z_{V} \approx 8.3$.Comment: 4 pages, 2 figures, submitted to PRL. 2 typos in ref. 15 were correcte

KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation.

KDM2B (also known as FBXL10) controls stem cell self-renewal, somatic cell reprogramming and senescence, and tumorigenesis. KDM2B contains multiple functional domains, including a JmjC domain that catalyzes H3K36 demethylation and a CxxC zinc-finger that recognizes CpG islands and recruits the polycomb repressive complex 1. Here, we report that KDM2B, via its F-box domain, functions as a subunit of the CUL1-RING ubiquitin ligase (CRL1/SCF(KDM2B)) complex. KDM2B targets c-Fos for polyubiquitylation and regulates c-Fos protein levels. Unlike the phosphorylation of other SCF (SKP1-CUL1-F-box)/CRL1 substrates that promotes substrates binding to F-box, epidermal growth factor (EGF)-induced c-Fos S374 phosphorylation dissociates c-Fos from KDM2B and stabilizes c-Fos protein. Non-phosphorylatable and phosphomimetic mutations at S374 result in c-Fos protein which cannot be induced by EGF or accumulates constitutively and lead to decreased or increased cell proliferation, respectively. Multiple tumor-derived KDM2B mutations impaired the function of KDM2B to target c-Fos degradation and to suppress cell proliferation. These results reveal a novel function of KDM2B in the negative regulation of cell proliferation by assembling an E3 ligase to targeting c-Fos protein degradation that is antagonized by mitogenic stimulations

The NMR of High Temperature Superconductors without Anti-Ferromagnetic Spin Fluctuations

A microscopic theory for the NMR anomalies of the planar Cu and O sites in superconducting La_1.85Sr_0.15CuO_4 is presented that quantitatively explains the observations without the need to invoke anit-ferromagnetic spin fluctuations on the planar Cu sites and its significant discrepancy with the observed incommensurate neutron spin fluctuations. The theory is derived from the recently published ab-initio band structure calculations that correct LDA computations tendency to overestimate the self-coulomb repulsion for the half-filled Cu d_x2-y2 orbital for these ionic systems. The new band structure leads to two bands at the Fermi level with holes in the Cu d_z2 and apical O p_z orbitals in addition to the standard Cu d_x2-y2 and planar O p_sigma orbitals. This band structure is part of a new theory for the cuprates that explains a broad range of experiments and is based upon the formation of Cooper pairs comprised of a k up spin electron from one band and a -k down spin electron from another band (Interband Pairing Model).Comment: In Press, Journal of Physical Chemistry. See also http://www.firstprinciples.com. Minor changes to references and figure readabilit

Nighttime chemistry at a high altitude site above Hong Kong

Nighttime reactions of nitrogen oxides influence ozone, volatile organic compounds, and aerosol and are thus important to the understanding of regional air quality. Despite large emissions and rapid recent growth of nitrogen oxide concentrations, there are few studies of nighttime chemistry in China. Here we present measurements of nighttime nitrogen oxides, NO3 and N2O5, from a coastal mountaintop site in Hong Kong adjacent to the megacities of the Pearl River Delta region. This is the first study of nighttime chemistry from a site within the residual layer in China. Key findings include the following. First, highly concentrated urban NOx outflow from the Pearl River Delta region was sampled infrequently at night, with N2O5 mixing ratios up to 8 ppbv (1 min average) or 12 ppbv (1 s average) in nighttime aged air masses. Second, the average N2O5 uptake coefficient was determined from a best fit to the available steady state lifetime data as γ(N2O5) = 0.014 ± 0.007. Although this determination is uncertain due to the difficulty of separating N2O5 losses from those of NO3, this value is in the range of previous residual layer determinations of N2O5 uptake coefficients in polluted air in North America. Third, there was a significant contribution of biogenic hydrocarbons to NO3 loss inferred from canister samples taken during daytime. Finally, daytime N2O5 mixing ratios were in accord with their predicted photochemical steady state. Heterogeneous uptake of N2O5 in fog is determined to be an important production mechanism for soluble nitrate, even during daytime. Key Points Large (up to 12 ppbv N2O5) but infrequent nocturnal NOx outflow from the Pearl River Delta Average N2O5 uptake coefficients 0.014 ± 0.007, in line with residual layer measurements in the U.S. Daytime N2O5 follows predicted steady state but rapidly produces soluble nitrate in fog.Department of Civil and Environmental Engineerin