Big-bang nucleosynthesis with a long-lived charged massive particle including 4^4He spallation processes

We propose helium-4 spallation processes induced by long-lived stau in supersymmetric standard models, and investigate an impact of the processes on light elements abundances. We show that, as long as the phase space of helium-4 spallation processes is open, they are more important than stau-catalyzed fusion and hence constrain the stau property.Comment: 12 pages, 4 figures, 1 table, references added, all figures correcte

Possible ΔΔ\Delta\Delta dibaryons in the quark cluster model

In the framework of RGM, the binding energy of one channel $\Delta\Delta_{(3,0)}$($d^*$) and $\Delta\Delta_{(0,3)}$ are studied in the chiral SU(3) quark cluster model. It is shown that the binding energies of the systems are a few tens of MeV. The behavior of the chiral field is also investigated by comparing the results with those in the SU(2) and the extended SU(2) chiral quark models. It is found that the symmetry property of the $\Delta\Delta$ system makes the contribution of the relative kinetic energy operator between two clusters attractive. This is very beneficial for forming the bound dibaryon. Meanwhile the chiral-quark field coupling also plays a very important role on binding. The S-wave phase shifts and the corresponding scattering lengths of the systems are also given.Comment: LeTex with 2 ps figure

Possible Dibaryons with Strangeness s=-5

In the framework of $RGM$, the binding energy of the six quark system with strangeness s=-5 is systematically investigated under the SU(3) chiral constituent quark model. The single $\Xi^*\Omega$ channel calculation with spins S=0 and 3 and the coupled $\Xi\Omega$ and $\Xi^*\Omega$ channel calculation with spins S=1 and 2 are considered, respectively. The results show following observations: In the spin=0 case, $\Xi^* \Omega$ is a bound dibaryon with the binding energy being $80.0 \sim 92.4 MeV$. In the S=1 case, $\Xi\Omega$ is also a bound dibaryon. Its binding energy is ranged from $26.2 MeV$ to $32.9 MeV$. In the S=2 and S=3 cases, no evidence of bound dibaryons are found. The phase shifts and scattering lengths in the S=0 and S=1 cases are also given.Comment: 10 pages, late

Rumination syndrome: Assessment of vagal tone during and after meals and during diaphragmatic breathing

Background: Pathophysiology of rumination syndrome (RS) is not well understood. Treatment with diaphragmatic breathing improves rumination syndrome. The aim of the study was to characterize vagal tone in patients with rumination syndrome during and after meals and during diaphragmatic breathing. Methods: We prospectively recruited 10 healthy volunteers (HV) and 10 patients with RS. Subjects underwent measurement of vagal tone using heart rate variability. Vagal tone was measured during baseline, test meal and intervention (diaphragmatic (DiaB), slow deep (SlowDB), and normal breathing). Vagal tone was assessed using mean values of root mean square of successive differences (RMSSD), and area under curves (AUC) were calculated for each period. We compared baseline RMSSD, the AUC and meal‐induced discomfort scores between HV and RS. Furthermore, we assessed the effect of respiratory exercises on symptom scores, and number of rumination episodes. Key Results: There was no significant difference in baseline vagal tone between HV and RS. During the postprandial period, there was a trend to higher vagal tone in RS, but not significantly (P > .2 for all). RS had the higher total symptom scores than HV (P < .011). In RS, only DiaB decreased the number of rumination episodes during the intervention period (P = .028), while both DiaB and SlowDB increased vagal tone (P < .05 for both). The symptom scores with the 3 breathing exercises showed very similar trends. Conclusions and inferences: Patients with RS do not have decreased vagal tone related to meals. DiaB reduced number of rumination events by a mechanism not related to changes in vagal tone

Potential Role of Protein Kinase B in Insulin-induced Glucose Transport, Glycogen Synthesis, and Protein Synthesis

Various biological responses stimulated by insulin have been thought to be regulated by phosphatidylinosi-tol 3-kinase, including glucose transport, glycogen syn-thesis, and protein synthesis. However, the molecular link between phosphatidylinositol 3-kinase and these biological responses has been poorly understood. Re-cently, it has been shown that protein kinase B (PKB/c-Akt/ Rac) lies immediately downstream from phosphati-dylinositol 3-kinase. Here, we show that expression of a constitutively active form of PKB induced glucose up-take, glycogen synthesis, and protein synthesis in L6 myotubes downstream of phosphatidylinositol 3-kinase and independent of Ras and mitogen-activated protein kinase activation. Introduction of constitutively active PKB induced glucose uptake and protein synthesis but not glycogen synthesis in 3T3L-1 adipocytes, which lack expression of glycogen synthase kinase 3 different from L6 myotubes. Furthermore, we show that deactivation of glycogen synthase kinase 3 and activation of rapamy-cin- sensitive serine/threonine kinase by PKB in L6 myo-tubes might be involved in the enhancement of glycogen synthesis and protein synthesis, respectively. These re-sults suggest that PKB acts as a key enzyme linking phosphatidylinositol 3-kinase activation to multiple bi-ological functions of insulin through regulation of downstream kinases in skeletal muscle, a major target tissue of insulin

Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis

SummaryCytosine methylation is important for transposon silencing and epigenetic regulation of endogenous genes, although the extent to which this DNA modification functions to regulate the genome is still unknown. Here we report the first comprehensive DNA methylation map of an entire genome, at 35 base pair resolution, using the flowering plant Arabidopsis thaliana as a model. We find that pericentromeric heterochromatin, repetitive sequences, and regions producing small interfering RNAs are heavily methylated. Unexpectedly, over one-third of expressed genes contain methylation within transcribed regions, whereas only ∼5% of genes show methylation within promoter regions. Interestingly, genes methylated in transcribed regions are highly expressed and constitutively active, whereas promoter-methylated genes show a greater degree of tissue-specific expression. Whole-genome tiling-array transcriptional profiling of DNA methyltransferase null mutants identified hundreds of genes and intergenic noncoding RNAs with altered expression levels, many of which may be epigenetically controlled by DNA methylation

Long- and medium-range components of the nuclear force in quark-model based calculations

Quark-model descriptions of the nucleon-nucleon interaction contain two main ingredients, a quark-exchange mechanism for the short-range repulsion and meson-exchanges for the medium- and long-range parts of the interaction. We point out the special role played by higher partial waves, and in particular the 1F3, as a very sensitive probe for the meson-exchange part employed in these interaction models. In particular, we show that the presently available models fail to provide a reasonable description of higher partial waves and indicate the reasons for this shortcoming.Comment: 19 pages, 7 figure

A Realistic Description of Nucleon-Nucleon and Hyperon-Nucleon Interactions in the SU_6 Quark Model

We upgrade a SU_6 quark-model description for the nucleon-nucleon and hyperon-nucleon interactions by improving the effective meson-exchange potentials acting between quarks. For the scalar- and vector-meson exchanges, the momentum-dependent higher-order term is incorporated to reduce the attractive effect of the central interaction at higher energies. The single-particle potentials of the nucleon and Lambda, predicted by the G-matrix calculation, now have proper repulsive behavior in the momentum region q_1=5 - 20 fm^-1. A moderate contribution of the spin-orbit interaction from the scalar-meson exchange is also included. As to the vector mesons, a dominant contribution is the quadratic spin-orbit force generated from the rho-meson exchange. The nucleon-nucleon phase shifts at the non-relativistic energies up to T_lab=350 MeV are greatly improved especially for the 3E states. The low-energy observables of the nucleon-nucleon and the hyperon-nucleon interactions are also reexamined. The isospin symmetry breaking and the Coulomb effect are properly incorporated in the particle basis. The essential feature of the Lambda N - Sigma N coupling is qualitatively similar to that obtained from the previous models. The nuclear saturation properties and the single-particle potentials of the nucleon, Lambda and Sigma are reexamined through the G-matrix calculation. The single-particle potential of the Sigma hyperon is weakly repulsive in symmetric nuclear matter. The single-particle spin-orbit strength for the Lambda particle is very small, in comparison with that of the nucleons, due to the strong antisymmetric spin-orbit force generated from the Fermi-Breit interaction.Comment: Revtex v2.09, 69 pages with 25 figure

The Two-Nucleon Potential from Chiral Lagrangians

Chiral symmetry is consistently implemented in the two-nucleon problem at low-energy through the general effective chiral lagrangian. The potential is obtained up to a certain order in chiral perturbation theory both in momentum and coordinate space. Results of a fit to scattering phase shifts and bound state data are presented, where satisfactory agreement is found for laboratory energies up to about 100 Mev.Comment: Postscript file; figures available by reques