Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age

Retrospective histologic analyses of bone biopsies and of post mortem samples from normal persons of different age groups, and of bone biopsies of age- and sex-matched groups of patients with primary osteoporosis and aplastic anemia show characteristic age dependent as well as pathologic changes including atrophy of osseous trabeculae and of hematopoiesis, and changes in the sinusoidal and arterial capillary compartments. These results indicate the possible role of a microvascular defect in the pathogenesis of osteoporosis and aplastic anemia

Cable compliance

The object of the investigation was to solve mechanical problems using cable-in-bending and cable-in-torsion. These problems included robotic contacts, targets, and controls using cable compliance. Studies continued in the use of cable compliance for the handicapped and the elderly. These included work stations, walkers, prosthetic knee joints, elbow joints, and wrist joints. More than half of these objects were met, and models were made and studies completed on most of the others. It was concluded that the many different and versatile solutions obtained only opened the door to many future challenges

Fluctuations of a long, semiflexible polymer in a narrow channel

We consider an inextensible, semiflexible polymer or worm-like chain, with persistence length $P$ and contour length $L$, fluctuating in a cylindrical channel of diameter $D$. In the regime $D\ll P\ll L$, corresponding to a long, tightly confined polymer, the average length of the channel $$ occupied by the polymer and the mean square deviation from the average vary as $=[1-\alpha_\circ(D/P)^{2/3}]L$ and $<\Delta R_\parallel^{\thinspace 2}\thinspace>=\beta_\circ(D^2/P)L$, respectively, where $\alpha_\circ$ and $\beta_\circ$ are dimensionless amplitudes. In earlier work we determined $\alpha_\circ$ and the analogous amplitude $\alpha_\Box$ for a channel with a rectangular cross section from simulations of very long chains. In this paper we estimate $\beta_\circ$ and $\beta_\Box$ from the simulations. The estimates are compared with exact analytical results for a semiflexible polymer confined in the transverse direction by a parabolic potential instead of a channel and with a recent experiment. For the parabolic confining potential we also obtain a simple analytic result for the distribution of $R_\parallel$ or radial distribution function, which is asymptotically exact for large $L$ and has the skewed shape seen experimentally.Comment: 21 pages, including 4 figure

Surface Critical Behavior of Binary Alloys and Antiferromagnets: Dependence of the Universality Class on Surface Orientation

The surface critical behavior of semi-infinite (a) binary alloys with a continuous order-disorder transition and (b) Ising antiferromagnets in the presence of a magnetic field is considered. In contrast to ferromagnets, the surface universality class of these systems depends on the orientation of the surface with respect to the crystal axes. There is ordinary and extraordinary surface critical behavior for orientations that preserve and break the two-sublattice symmetry, respectively. This is confirmed by transfer-matrix calculations for the two-dimensional antiferromagnet and other evidence.Comment: Final version that appeared in PRL, some minor stylistic changes and one corrected formula; 4 pp., twocolumn, REVTeX, 3 eps fig

Simulation of a semiflexible polymer in a narrow cylindrical pore

The probability that a randomly accelerated particle in two dimensions has not yet left a simply connected domain ${\cal A}$ after a time $t$ decays as $e^{-E_0t}$ for long times. The same quantity $E_0$ also determines the confinement free energy per unit length $\Delta f=k_BT\thinspace E_0$ of a semiflexible polymer in a narrow cylindrical pore with cross section ${\cal A}$. From simulations of a randomly accelerated particle we estimate the universal amplitude of $\Delta f$ for both circular and rectangular cross sections.Comment: 10 pages, 2 eps figure

Conformal off-diagonal boundary density profiles on a semi-infinite strip

The off-diagonal profile phi(v) associated with a local operator (order parameter or energy density) close to the boundary of a semi-infinite strip with width L is obtained at criticality using conformal methods. It involves the surface exponent x_phi^s and displays a simple universal behaviour which crosses over from surface finite-size scaling when v/L is held constant to corner finite-size scaling when v/L -> 0.Comment: 5 pages, 1 figure, IOP macros and eps

Casimir Forces between Spherical Particles in a Critical Fluid and Conformal Invariance

Mesoscopic particles immersed in a critical fluid experience long-range Casimir forces due to critical fluctuations. Using field theoretical methods, we investigate the Casimir interaction between two spherical particles and between a single particle and a planar boundary of the fluid. We exploit the conformal symmetry at the critical point to map both cases onto a highly symmetric geometry where the fluid is bounded by two concentric spheres with radii R_- and R_+. In this geometry the singular part of the free energy F only depends upon the ratio R_-/R_+, and the stress tensor, which we use to calculate F, has a particularly simple form. Different boundary conditions (surface universality classes) are considered, which either break or preserve the order-parameter symmetry. We also consider profiles of thermodynamic densities in the presence of two spheres. Explicit results are presented for an ordinary critical point to leading order in epsilon=4-d and, in the case of preserved symmetry, for the Gaussian model in arbitrary spatial dimension d. Fundamental short-distance properties, such as profile behavior near a surface or the behavior if a sphere has a `small' radius, are discussed and verified. The relevance for colloidal solutions is pointed out.Comment: 37 pages, 2 postscript figures, REVTEX 3.0, published in Phys. Rev. B 51, 13717 (1995

Local functional models of critical correlations in thin-films

Recent work on local functional theories of critical inhomogeneous fluids and Ising-like magnets has shown them to be a potentially exact, or near exact, description of universal finite-size effects associated with the excess free-energy and scaling of one-point functions in critical thin films. This approach is extended to predict the two-point correlation function G in critical thin-films with symmetric surface fields in arbitrary dimension d. In d=2 we show there is exact agreement with the predictions of conformal invariance for the complete spectrum of correlation lengths as well as the detailed position dependence of the asymptotic decay of G. In d=3 and d>=4 we present new numerical predictions for the universal finite-size correlation length and scaling functions determining the structure of G across the thin-film. Highly accurate analytical closed form expressions for these universal properties are derived in arbitrary dimension.Comment: 4 pages, 1 postscript figure. Submitted to Phys Rev Let

Critical behaviour near multiple junctions and dirty surfaces in the two-dimensional Ising model

We consider m two-dimensional semi-infinite planes of Ising spins joined together through surface spins and study the critical behaviour near to the junction. The m=0 limit of the model - according to the replica trick - corresponds to the semi-infinite Ising model in the presence of a random surface field (RSFI). Using conformal mapping, second-order perturbation expansion around the weakly- and strongly-coupled planes limits and differential renormalization group, we show that the surface critical behaviour of the RSFI model is described by Ising critical exponents with logarithmic corrections to scaling, while at multiple junctions (m>2) the transition is first order. There is a spontaneous junction magnetization at the bulk critical point.Comment: Old paper, for archiving. 6 pages, 1 figure, IOP macro, eps

Non-Universal Critical Behaviour of Two-Dimensional Ising Systems

Two conditions are derived for Ising models to show non-universal critical behaviour, namely conditions concerning 1) logarithmic singularity of the specific heat and 2) degeneracy of the ground state. These conditions are satisfied with the eight-vertex model, the Ashkin-Teller model, some Ising models with short- or long-range interactions and even Ising systems without the translational or the rotational invariance.Comment: 17 page