699 research outputs found
Performance and stall limits of a YTF30-P-1 turbofan engine with uniform inlet flow
Performance and stall limits of YTF30-P-1 turbofan engine with uniform compressor inlet flo
Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organs
Previous studies suggested the expression of mRNA, coding for CNP, exclusively in the central nervous system. In the present study, using the polymerase chain reaction (PCR) technique instead of the less sensitive Northern blot hybridization, CNP-specific sequences have also been detected in rat atria and ventricles of the heart as well as in organs of the immune system (thymus, spleen and lymph nodes). Parallel PCR-assays documented ANP-mRNA in these tissues. To verify specificity of the PCR-products, Southern blots have been hybridized with a third internal oligonucleotide and amplification products have been sequenced. The relative level of CNP-mRNA in these tissues was estimated to be in the range of 1-9% of total brain CNP transcripts. The results suggest that the peptide may have a peripheral as well as a central site of action. In light of its pronounced effect on cell proliferation, particular interest should focus on a possible role of CNP in the immune system
Counter Machines and Distributed Automata: A Story about Exchanging Space and Time
We prove the equivalence of two classes of counter machines and one class of
distributed automata. Our counter machines operate on finite words, which they
read from left to right while incrementing or decrementing a fixed number of
counters. The two classes differ in the extra features they offer: one allows
to copy counter values, whereas the other allows to compute copyless sums of
counters. Our distributed automata, on the other hand, operate on directed path
graphs that represent words. All nodes of a path synchronously execute the same
finite-state machine, whose state diagram must be acyclic except for
self-loops, and each node receives as input the state of its direct
predecessor. These devices form a subclass of linear-time one-way cellular
automata.Comment: 15 pages (+ 13 pages of appendices), 5 figures; To appear in the
proceedings of AUTOMATA 2018
A Bit-String Model for Biological Aging
We present a simple model for biological aging. We studied it through
computer simulations and we have found this model to reflect some features of
real populations.Comment: LaTeX file, 4 PS figures include
Bounded Languages Meet Cellular Automata with Sparse Communication
Cellular automata are one-dimensional arrays of interconnected interacting
finite automata. We investigate one of the weakest classes, the real-time
one-way cellular automata, and impose an additional restriction on their
inter-cell communication by bounding the number of allowed uses of the links
between cells. Moreover, we consider the devices as acceptors for bounded
languages in order to explore the borderline at which non-trivial decidability
problems of cellular automata classes become decidable. It is shown that even
devices with drastically reduced communication, that is, each two neighboring
cells may communicate only constantly often, accept bounded languages that are
not semilinear. If the number of communications is at least logarithmic in the
length of the input, several problems are undecidable. The same result is
obtained for classes where the total number of communications during a
computation is linearly bounded
Exact Solution of an Evolutionary Model without Ageing
We introduce an age-structured asexual population model containing all the
relevant features of evolutionary ageing theories. Beneficial as well as
deleterious mutations, heredity and arbitrary fecundity are present and managed
by natural selection. An exact solution without ageing is found. We show that
fertility is associated with generalized forms of the Fibonacci sequence, while
mutations and natural selection are merged into an integral equation which is
solved by Fourier series. Average survival probabilities and Malthusian growth
exponents are calculated indicating that the system may exhibit mutational
meltdown. The relevance of the model in the context of fissile reproduction
groups as many protozoa and coelenterates is discussed.Comment: LaTeX file, 15 pages, 2 ps figures, to appear in Phys. Rev.
Feasibility of multimodal 3D neuroimaging to guide implantation of intracranial EEG electrodes
Since intracranial electrode implantation has limited spatial sampling and carries significant risk, placement has to be effective and efficient. Structural and functional imaging of several different modalities contributes to localising the seizure onset zone (SoZ) and eloquent cortex. There is a need to summarise and present this information throughout the pre/intra/post-surgical course
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