23 research outputs found
Increased risk of everolimus-associated acute kidney injury in cancer patients with impaired kidney function
Full text linkDelayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model
Get PDFThe immunosuppressive mammalian target of rapamycin (mTOR) inhibitors are widely used in solid organ transplantation, but their effect on kidney disease progression is controversial. mTOR has emerged as one of the main pathways regulating cell growth, proliferation, differentiation, migration, and survival. The aim of this study was to analyze the effects of delayed inhibition of mTOR pathway with low dose of everolimus on progression of renal disease and TGFβ expression in the 5/6 nephrectomy model in Wistar rats
The role of ethnic differences, structural background and process characteristics in the family in preschool children’s language proficiency
No full textBrainhack: Developing a culture of open, inclusive, community-driven neuroscience
Get PDFBrainhack is an innovative meeting format that promotes scientific collaboration and education in an open, inclusive environment. This NeuroView describes the myriad benefits for participants and the research community and how Brainhacks complement conventional formats to augment scientific progress
The mTOR Inhibitor Everolimus Attenuates the Time Course of Chronic Anti-Thy1 Nephritis in the Rat
No full textLong-Term Gene Therapy with Thrombospondin 2 Inhibits TGF-β Activation, Inflammation and Angiogenesis in Chronic Allograft Nephropathy
No full textRisk and Resilience Analysis of Public Civil Buildings Against Shelling with Explosive Sources in Urban Contexts
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