1,382 research outputs found
Fabrication and Characterization of Electrostatic Quantum Dots in a Si/SiGe 2D Electron Gas, Including an Integrated Read-out Channel
A new fabrication technique is used to produce quantum dots with read-out
channels in silicon/silicon-germanium two-dimensional electron gases. The
technique utilizes Schottky gates, placed on the sides of a shallow etched
quantum dot, to control the electronic transport process. An adjacent quantum
point contact gate is integrated to the side gates to define a read-out channel
and thus allow for noninvasive detection of the electronic occupation of the
quantum dot. Reproducible and stable Coulomb oscillations and the corresponding
jumps in the read-out channel resistance are observed at low temperatures. The
fabricated dot combined with the read-out channel represent a step towards the
spin-based quantum bit in Si/SiGe heterostructures.Comment: 3 pages, 4 fig
Coherent back-scattering near the two-dimensional metal-insulator transition
We have studied corrections to conductivity due to the coherent
backscattering in low-disordered two-dimensional electron systems in silicon
for a range of electron densities including the vicinity of the metal-insulator
transition, where the dramatic increase of the spin susceptibility has been
observed earlier. We show that the corrections, which exist deeper in the
metallic phase, weaken upon approaching to the transition and practically
vanish at the critical density, thus suggesting that the localization is
suppressed near and at the transition even in zero field.Comment: to appear in PR
Cytomegalovirus infection of the upper gastrointestinal tract following liver transplantation—incidence, location, and severity in cyclosporine- and FK506-treated patients
One hundred and forty randomly selected liver transplant recipients were studied before and after primary orthotopic liver transplantation for the presence or absence of CMV enteritis. Following OLTx, 65 patients were treated with cyclosporine A and 75 were treated with FK506. The two groups were similar with regard to the incidence, location, and outcome of their upper gastrointestinal CMV infection. Prior to OLTx, only one patient had evidence of enteric CMV infection. The incidence of CMV enteritis post-OLTx was 27.7% in the CsA-treated group and 20% in the FK-treated group. During the first posttransplant month, no patient in the FK-treated group developed CMV enteritis, compared with 11.5% of the patients who were treated with CsA (P<0.05). Gastric CMV was found in over 80% of those positive for any organ in either group. In addition to CMV infection of the upper gastrointestinal tract, clinically evident CMV disease involved more nonenteric organs in the CsA-treated group than in the FK-treated group. In the CsA-treated group, CMV-negative patients had a statistically higher 1-year survival rate (100%) than CMV-positive patients (77.8%) (P<0.05). In the FK-treated group, no difference in survival was observed between CMV-positive or CMV-negative cases at 1 year. Of the patients on CsA, 20% received OKT3 for persistent rejection, as compared with 13% in the FK-treated group. The patients receiving both CsA and OKT3 had a higher rate of upper gastrointestinal CMV infection than did FK-treated patients who also received OKT3 therapy (38.5% versus 20%, respectively). Based upon these data, it can be concluded that (1) patients receiving FK have a lower incidence of enteric CMV infection; (2) following OLTx, upper gastrointestinal CMV infection presents later in FK-treated patients; (3) the stomach is the most frequently involved organ in the UGIT; (4) FK-treated liver recipients have less severe enteric CMV infection than do CsA-treated patients; (5) enteric CMV is not a major cause of mortality in liver trans lant recipients; and (6) in patients receiving FK, those who require OKT3 therapy do not appear to be at a greater risk for the development of CMV enteritis than those who do not. © 1992 by Williams & Wilkins
Factors associated with Mortality in Adults admitted with Heart Failure at the University Teaching Hospital in Lusaka, Zambia
Background: Heart failure is a major public health problem and has been recognized as an important cause of morbidity and mortality for several years. It is one of the leading non-infectious causes of death among hospitalized patients at the University Teaching Hospital (UTH) in Lusaka, Zambia. This study aimed to investigate the predictors of 30-day mortality in heart failure patients admitted to the medical wards at the UTH using routinely obtained clinical data.Methods: We enrolled 390 heart failure patients and followed them up over a period of 30 days. Data collected included demographic characteristics (age, sex), medication use and co-morbidities (hypertension, diabetes mellitus, Human Immunodeficiency Virus (HIV) infection). Clinical data included vital signs, blood urea, serum sodium, serum potassium, serum creatinine, and haemoglobin level. Trans-thoracic echocardiographs and electrocardiographs were also done to determine left ventricular ejection fraction (LVEF) and to check for the presence of arrhythmias. Patients were dichotomized into those with preserved (LVEF>=40 percent) and reduced (LVEF< 40 percent) systolic function. Recruited patients were then prospectively followed up to determine outcome by day 30 (i.e. dead or alive). Cox proportion Hazard regression analysis (on Epi Info software version 3.5.3) was used to analyse the effect of each of these parameters on outcome.Results: Of the recruited patients, 59% were female (95% CI 54-64). The median age was 50 years (IQR 33-68). 138 patients (35%, 95% CI 31-40) died within 30 days of admission. 94 (68%) of these deaths occurred in-hospital. The factors shown to be independent predictors of death onmultivariate logistic regression analysis were LVEF<40 percent (OR=2.86, 95%CI 1.68- 4.87), NYHA class IV (OR=2.15, 95%CI 1.27- 3.64),serum urea above 15mmol/L (OR=2.48, 95%CI 1.07-5.70), and haemoglobin level below 12g/dL (OR=1.79, 95%CI 1.11- 2.89).The additional factor associated with increased risk of mortality on univariate analysis wassystolic blood pressure below 115mmHg (OR=1.63, 95%CI 1.05- 2.51). However, serum creatinine (OR=1.49, 95%CI 0.49-4.48) and HIV seropositivity (OR=0.96, 95% CI 0.53-1.72)had no bearing on the risk of death in this patient population.Conclusions: Left ventricular ejection fraction <40 percent, New York Heart Association class IV, serum urea above 15mmol/L, haemoglobin level below 12g/dLand systolic blood pressure below 115mmHg are predictors of poor 30-day outcome in hospitalised heart failure patients
Effect of Different Factors on the Service Life of Concrete Structures in Chloride Environments: A Parametric Study – Part One
This paper presents a comprehensive parametric study to determine the effect of different factors on the service life of reinforced concrete structures in chloride-laden environment. A model for corrosion initiation is selected and solved numerically by Finite Element Method for one-dimensional diffusion problem. It has been found that increase in water to cement ratio by 12.5%-50% in range of 0.20-0.40reduces the service life by 8%-35%, and by 7.35%-30.5% for the range 0.40-0.60. Also, the increase in concrete cover in the range of 20-35 mm by 14%-42%increases the service life by 8.1%-25.8%, and in the range of 35-60 mm by 7.7%-21.8%.Regarding mineral admixtures, the addition of fly ash and blast-furnace slag resulted in enhances the service life by 8%-70.7% due to increase of age factor by 25%-200%. Moreover,the addition of silica fume by 5%-15% increases the service life by 25.5%-80.6%.Finally, the rise of temperature by 25%-75% reduces the service life by 6.45%-18.7%, and the reduction of relative humidity by 25%-50% increases the life by 21.2%-89%. These values are based on a conservative approach and tend to guide the practice engineer on how these parameters affect service life of concrete structures
Survival or Sustainability? Contributions of Innovatively-Managed News Ventures to the Future of Egyptian Journalism
In the repressive political climate prevailing in Egypt in 2013-15, news ventures aspiring to high standards of reporting were forced to innovate. This paper analyses three Egyptian start-ups that experimented with novel revenue streams and news services during that period, to gain insights into their approaches to managing journalism. In the process it compares different criteria for assessing sustainability and concludes that, in adverse political environments, narrow economic measures of profitability and survival may give a misleading picture as to the sustainability of the kind of journalism conducive to democratic practice. Operating collaboratively, transparently and ethically may slow productivity and profitability in the short term while laying stronger foundations for durable relations among media teams, as well as with readers and advertisers, in the long run
Effect of Different Factors on the Service Life of Concrete Structures in Chloride Environment: A Parametric Study - Part Two
In this paper, the effect of different factors on the service life of reinforced concrete structures in marine environments is investigated through a parametric study. The considered case for the study was the two- dimensional diffusion problem. By solving the selected model for corrosion initiation by Finite Element Method, it has been concluded that, corrosion initiates at corner bars before side bars. Also, concrete elements subjected to two-dimensional diffusion are more susceptible to corrosion initiation than elements subjected to one-dimensional diffusion. Moreover, increase in water to cement ratio by 12.5%-50% in range 0.20-0.40 reduces the service life by 6.2%-31%, and by 5.3%-16.9% for the range 0.40-0.60. And, the increase in concrete cover in the range of 20-40 mm by 12.5% - 50% increases the service life by 5.1%-18.8%, and in the range of 35-60 mm by 2.9%-10.3%. The addition of fly ash and blast-furnace slag increased the service life by 6.35%-69.7% due to increase of age factor by 25%-200%. Furthermore, the addition of silica fume by 5%-15% increases the service life by 21.7%-81.2%. Regarding the environmental factors, increasing of temperature by 25%-75% reduces service life by 4.7%-12.75%, and reducing of relative humidity by 25%-50% increases the life by 17.5%-90.4%.are also given
FE Modeling of CFRP-Retrofitted RC Frames with Masonry Infill Walls
A number of numerical and experimental studies have been reported in recent literature to investigate the effects of infill walls on the seismic response of RC infilled frames. Many experimental studies used CFRP sheets as an external bracing system for retrofitting the infilled RC frames. It has been found that the common mode of failure of such retrofitted frames is the debonding of the CFRP-concrete adhesive material. In the current study, the behaviour of CFRP retrofitted infilled RC frames was investigated with a finite element micro model. In that model, a four-node shell element was used for modeling the concrete, infill panel and CFRP sheets. The interaction between concrete frame and infill panel was modelled using contact surfaces to allow the occurrence of separation and prevent penetration. Nonlinearities of the concrete, infill panel, steel and CFRP sheets were considered. To allow the occurrence of debonding mode of failure, the adhesive layer was modelled using cohesive surface-to-surface interaction model, which assumes that the failure of cohesive bond is characterized by progressive degradation of the cohesive stiffness, which is driven by a damage process based on the fracture energy. The proposed model was verified using experimental results from the literature. Results indicated that the cohesive model could capture the debonding mode of failure which has been observed experimentally. The validated micro model was used to investigate the effects of the strip end area, the anchor location and partial bonding of the CFRP sheet to the infill panel surface on the behaviour of infilled frames. The results of parametric study showed that, to get the highest efficiency of the CFRP retrofitted infilled frame, bonding about 25% only of the diagonal length from each end is sufficient to get the same behaviour of the totally bonded sheet
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