Courseware in academic library user education: a literature review from the GAELS Joint Electronic Library project

The use of courseware for information skills teaching in academic libraries has been growing for a number of years. The GAELS project was required to create a set of learning materials to support Joint Electronic Library activity at Glasgow and Strathclyde Universities and conducted a literature review of the subject. This review discovered a range of factors common to successful library courseware implementations, such as the need for practitioners to feel a sense of ownership of the medium, a need for courseware customization to local information environments, and an emphasis on training packages for large bodies of undergraduates. However, we also noted underdeveloped aspects worthy of further attention, such as treatment of pedagogic issues in library CAL implementations and use of hypertextual learning materials for more advanced information skills training. We suggest ways of improving library teaching practice and further areas of research

Variable Interstellar Absorption toward the Halo Star HD 219188 - Implications for Small-Scale Interstellar Structure

Within the last 10 years, strong, narrow Na I absorption has appeared at v_sun ~ -38 km/s toward the halo star HD 219188; that absorption has continued to strengthen, by a factor 2-3, over the past three years. The line of sight appears to be moving into/through a relatively cold, quiescent intermediate velocity (IV) cloud, due to the 13 mas/yr proper motion of HD 219188; the variations in Na I probe length scales of 2-38 AU/yr. UV spectra obtained with the HST GHRS in 1994-1995 suggest N(H_tot) ~ 4.8 X 10^{17} cm^{-2}, ``halo cloud'' depletions, n_H ~ 25 cm^{-3}, and n_e ~ 0.85-6.2 cm^{-3} (if T ~ 100 K) for the portion of the IV cloud sampled at that time. The relatively high fractional ionization, n_e/n_H >~ 0.034, implies that hydrogen must be partially ionized. The N(Na I)/N(H_tot) ratio is very high; in this case, the variations in Na I do not imply large local pressures or densities.Comment: 12 pages; aastex; to appear in ApJ

Crossing the LINE Toward Genomic Instability: LINE-1 Retrotransposition in Cancer

Retrotransposons are repetitive DNA sequences that are positioned throughout the human genome. Retrotransposons are capable of copying themselves and mobilizing new copies to novel genomic locations in a process called retrotransposition. While most retrotransposon sequences in the human genome are incomplete and incapable of mobilization, the LINE-1 retrotransposon, which comprises approximately 17% of the human genome, remains active. The disruption of cellular mechanisms that suppress retrotransposon activity is linked to the generation of aneuploidy, a potential driver of tumor development. When retrotransposons insert into a novel genomic region, they have the potential to disrupt the coding sequence of endogenous genes and alter gene expression, which can lead to deleterious consequences for the organism. Additionally, increased LINE-1 copy numbers provide more chances for recombination events to occur between retrotransposons, which can lead to chromosomal breaks and rearrangements. LINE-1 activity is increased in various cancer cell lines and in patient tissues resected from primary tumors. LINE-1 activity also correlates with increased cancer metastasis. This review aims to give a brief overview of the connections between LINE-1 retrotransposition and the loss of genome stability. We will also discuss the mechanisms that repress retrotransposition in human cells and their links to cancer

Courseware in academic library user education: a literature review from the GAELS Joint Electronic Library project

The use of courseware for information skills teaching in academic libraries has been growing for a number of years. The GAELS project was required to create a set of learning materials to support Joint Electronic Library activity at Glasgow and Strathclyde Universities and conducted a literature review of the subject. This review discovered a range of factors common to successful library courseware implementations, such as the need for practitioners to feel a sense of ownership of the medium, a need for courseware customization to local information environments, and an emphasis on training packages for large bodies of undergraduates. However, we also noted underdeveloped aspects worthy of further attention, such as treatment of pedagogic issues in library CAL implementations and use of hypertextual learning materials for more advanced information skills training. We suggest ways of improving library teaching practice and further areas of research

Microwave oven fabricated hybrid memristor devices for non-volatile memory storage

© 2014 IOP Publishing Ltd. Novel hybrid non-volatile memories made using an ultra-fast microwave heating method are reported for the first time. The devices, consisting of aligned ZnO nanorods embedded in poly (methyl methacrylate), require no forming step and exhibit reliable and reproducible bipolar resistive switching at low voltages and with low power usage. We attribute these properties to a combination of the high aspect ratio of the nanorods and the polymeric hybrid structure of the device. The extremely easy, fast and low-cost solution based method of fabrication makes possible the simple and quick production of cheap memory cells

Monitoring the Variable Interstellar Absorption toward HD 219188 with HST/STIS

We discuss the results of continued spectroscopic monitoring of the variable intermediate-velocity (IV) absorption at v = -38 km/s toward HD 219188. After reaching maxima in mid-2000, the column densities of both Na I and Ca II in that IV component declined by factors >= 2 by the end of 2006. Comparisons between HST/STIS echelle spectra obtained in 2001, 2003, and 2004 and HST/GHRS echelle spectra obtained in 1994--1995 indicate the following: (1) The absorption from the dominant species S II, O I, Si II, and Fe II is roughly constant in all four sets of spectra -- suggesting that the total N(H) and the (mild) depletions have not changed significantly over a period of nearly ten years. (2) The column densities of the trace species C I (both ground and excited fine-structure states) and of the excited state C II* all increased by factors of 2--5 between 1995 and 2001 -- implying increases in the hydrogen density n_H (from about 20 cm^{-3} to about 45 cm^{-3}) and in the electron density n_e (by a factor >= 3) over that 6-year period. (3) The column densities of C I and C II* -- and the corresponding inferred n_H and n_e -- then decreased slightly between 2001 and 2004. (4) The changes in C I and C II* are very similar to those seen for Na I and Ca II. The relatively low total N(H) and the modest n_H suggest that the -38 km/s cloud toward HD 219188 is not a very dense knot or filament. Partial ionization of hydrogen appears to be responsible for the enhanced abundances of Na I, C I, Ca II, and C II*. In this case, the variations in those species appear to reflect differences in density and ionization [and not N(H)] over scales of tens of AU.Comment: 33 pages, 6 figures, aastex, accepted to Ap

Laser-heated rocket studies

CW laser heated rocket propulsion was investigated in both the flowing core and stationary core configurations. The laser radiation considered was 10.6 micrometers, and the working gas was unseeded hydrogen. The areas investigated included initiation of a hydrogen plasma capable of absorbing laser radiation, the radiation emission properties of hot, ionized hydrogen, the flow of hot hydrogen while absorbing and radiating, the heat losses from the gas and the rocket performance. The stationary core configuration was investigated qualitatively and semi-quantitatively. It was found that the flowing core rockets can have specific impulses between 1,500 and 3,300 sec. They are small devices, whose heating zone is only a millimeter to a few centimeters long, and millimeters to centimeters in radius, for laser power levels varying from 10 to 5,000 kW, and pressure levels of 3 to 10 atm. Heat protection of the walls is a vital necessity, though the fraction of laser power lost to the walls can be as low as 10% for larger powers, making the rockets thermally efficient