861 research outputs found
Universal Behavior of the Resistance Noise across the Metal-Insulator Transition in Silicon Inversion Layers
Studies of low-frequency resistance noise show that the glassy freezing of
the two-dimensional (2D) electron system in the vicinity of the metal-insulator
transition occurs in all Si inversion layers. The size of the metallic glass
phase, which separates the 2D metal and the (glassy) insulator, depends
strongly on disorder, becoming extremely small in high-mobility samples. The
behavior of the second spectrum, an important fourth-order noise statistic,
indicates the presence of long-range correlations between fluctuators in the
glassy phase, consistent with the hierarchical picture of glassy dynamics.Comment: revtex4; 4+ pages, 5 figure
Spin-independent origin of the strongly enhanced effective mass in a dilute 2D electron system
We have accurately measured the effective mass in a dilute two-dimensional
electron system in silicon by analyzing temperature dependence of the
Shubnikov-de Haas oscillations in the low-temperature limit. A sharp increase
of the effective mass with decreasing electron density has been observed. Using
tilted magnetic fields, we have found that the enhanced effective mass is
independent of the degree of spin polarization, which points to a
spin-independent origin of the mass enhancement and is in contradiction with
existing theories
Constraints on the Formation and Evolution of Circumstellar Disks in Rotating Magnetized Cloud Cores
We use magnetic collapse models to place some constraints on the formation
and angular momentum evolution of circumstellar disks which are embedded in
magnetized cloud cores. Previous models have shown that the early evolution of
a magnetized cloud core is governed by ambipolar diffusion and magnetic
braking, and that the core takes the form of a nonequilibrium flattened
envelope which ultimately collapses dynamically to form a protostar. In this
paper, we focus on the inner centrifugally-supported disk, which is formed only
after a central protostar exists, and grows by dynamical accretion from the
flattened envelope. We estimate a centrifugal radius for the collapse of mass
shells within a rotating, magnetized cloud core. The centrifugal radius of the
inner disk is related to its mass through the two important parameters
characterizing the background medium: the background rotation rate \Omb and
the background magnetic field strength \Bref. We also revisit the issue of
how rapidly mass is deposited onto the disk (the mass accretion rate) and use
several recent models to comment upon the likely outcome in magnetized cores.
Our model predicts that a significant centrifugal disk (much larger than a
stellar radius) will be present in the very early (Class 0) stage of
protostellar evolution. Additionally, we derive an upper limit for the disk
radius as it evolves due to internal torques, under the assumption that the
star-disk system conserves its mass and angular momentum even while most of the
mass is transferred to a central star.Comment: 23 pages, 1 figure, aastex, to appear in the Astrophysical Journal
(10 Dec 1998
Spinning Conformal Correlators
We develop the embedding formalism for conformal field theories, aimed at
doing computations with symmetric traceless operators of arbitrary spin. We use
an index-free notation where tensors are encoded by polynomials in auxiliary
polarization vectors. The efficiency of the formalism is demonstrated by
computing the tensor structures allowed in n-point conformal correlation
functions of tensors operators. Constraints due to tensor conservation also
take a simple form in this formalism. Finally, we obtain a perfect match
between the number of independent tensor structures of conformal correlators in
d dimensions and the number of independent structures in scattering amplitudes
of spinning particles in (d+1)-dimensional Minkowski space.Comment: 46 pages, 3 figures; V2: references added; V3: tiny misprint
corrected in (A.9
New markers of inflammation-induced renal injury subside when endotoxin tolerance develops in humans as measured by urine proteomics
Nonlocality vs. complementarity: a conservative approach to the information problem
A proposal for resolution of the information paradox is that "nice slice"
states, which have been viewed as providing a sharp argument for information
loss, do not in fact do so as they do not give a fully accurate description of
the quantum state of a black hole. This however leaves an information
*problem*, which is to provide a consistent description of how information
escapes when a black hole evaporates. While a rather extreme form of
nonlocality has been advocated in the form of complementarity, this paper
argues that is not necessary, and more modest nonlocality could solve the
information problem. One possible distinguishing characteristic of scenarios is
the information retention time. The question of whether such nonlocality
implies acausality, and particularly inconsistency, is briefly addressed. The
need for such nonlocality, and its apparent tension with our empirical
observations of local quantum field theory, may be a critical missing piece in
understanding the principles of quantum gravity.Comment: 11 pages of text and figures, + references. v2 minor text. v3 small
revisions to match final journal versio
Sample size requirements for separating out the effects of combination treatments: Randomised controlled trials of combination therapy vs. standard treatment compared to factorial designs for patients with tuberculous meningitis
<p>Abstract</p> <p>Background</p> <p>In certain diseases clinical experts may judge that the intervention with the best prospects is the addition of two treatments to the standard of care. This can either be tested with a simple randomized trial of combination versus standard treatment or with a 2 × 2 factorial design.</p> <p>Methods</p> <p>We compared the two approaches using the design of a new trial in tuberculous meningitis as an example. In that trial the combination of 2 drugs added to standard treatment is assumed to reduce the hazard of death by 30% and the sample size of the combination trial to achieve 80% power is 750 patients. We calculated the power of corresponding factorial designs with one- to sixteen-fold the sample size of the combination trial depending on the contribution of each individual drug to the combination treatment effect and the strength of an interaction between the two.</p> <p>Results</p> <p>In the absence of an interaction, an eight-fold increase in sample size for the factorial design as compared to the combination trial is required to get 80% power to jointly detect effects of both drugs if the contribution of the less potent treatment to the total effect is at least 35%. An eight-fold sample size increase also provides a power of 76% to detect a qualitative interaction at the one-sided 10% significance level if the individual effects of both drugs are equal. Factorial designs with a lower sample size have a high chance to be underpowered, to show significance of only one drug even if both are equally effective, and to miss important interactions.</p> <p>Conclusions</p> <p>Pragmatic combination trials of multiple interventions versus standard therapy are valuable in diseases with a limited patient pool if all interventions test the same treatment concept, it is considered likely that either both or none of the individual interventions are effective, and only moderate drug interactions are suspected. An adequately powered 2 × 2 factorial design to detect effects of individual drugs would require at least 8-fold the sample size of the combination trial.</p> <p>Trial registration</p> <p>Current Controlled Trials <a href="http://www.controlled-trials.com/ISRCTN61649292">ISRCTN61649292</a></p
Conformal symmetry in non-local field theories
We have shown that a particular class of non-local free field theory has
conformal symmetry in arbitrary dimensions. Using the local field theory
counterpart of this class, we have found the Noether currents and Ward
identities of the translation, rotation and scale symmetries. The operator
product expansion of the energy-momentum tensor with quasi-primary fields is
also investigated.Comment: 15 pages, V2 (Some references added) V3(published version
RG flow of transport quantities
The RG flow equation of various transport quantities are studied in arbitrary
spacetime dimensions, in the fixed as well as fluctuating background geometry
both for the Maxwellian and DBI type of actions. The regularity condition on
the flow equation of the conductivity at the horizon for the DBI action
reproduces naturally the leading order result of {\it Hartnoll et al.}, [{\it
JHEP}, {\bf 04}, 120 (2010)]. Motivated by the result of {\it van der Marel et
al.}, [{\it science}, {\bf 425}, 271 (2003], we studied, analytically, the
conductivity versus frequency plane by dividing it into three distinct parts:
and . In order to compare, we choose 3+1
dimensional bulk spacetime for the computation of the conductivity. In the
range, the conductivity does not show up the Drude like form in any
spacetime dimensions. In the range and staying away from the
horizon, for the DBI action with unit dynamical exponent, non-zero magnetic
field and charge density, the conductivity goes as , whereas the
phase of the conductivity, goes as,
and . There exists a universal
quantity at the horizon that is the phase angle of conductivity, which either
vanishes or an integral multiple of . Furthermore, we calculate the
temperature dependence to the thermoelectric and the thermal conductivity at
the horizon. The charge diffusion constant for the DBI action is studied.Comment: 1+68 pages, 12 figures and 4 appendices; V2: The charge diffusion
constant is calculated for arbitrary spacetime dimensions and related
references added; v3: Connection with the RG flow of 1010.4036 is made; v4:
Several corrections, typos fixed and a ref. adde
Making predictions in the multiverse
I describe reasons to think we are living in an eternally inflating
multiverse where the observable "constants" of nature vary from place to place.
The major obstacle to making predictions in this context is that we must
regulate the infinities of eternal inflation. I review a number of proposed
regulators, or measures. Recent work has ruled out a number of measures by
showing that they conflict with observation, and focused attention on a few
proposals. Further, several different measures have been shown to be
equivalent. I describe some of the many nontrivial tests these measures will
face as we learn more from theory, experiment, and observation.Comment: 20 pages, 3 figures; invited review for Classical and Quantum
Gravity; v2: references improve
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