577 research outputs found
Video information system
Computerized information storage and display system directs storage of documents, drawings, photographs, fingerprints, etc., and permits rapid retrieval for real-time viewing on remote consoles
A new polymorph of phenylselenium trichloride
A second polymorph of phenylselenium trichloride, PhSeCl3 or C6H5Cl3Se, is
disclosed, which is comprised of asymmetric chlorine-bridged noncovalent
dimer units rather than polymeric chains. These dimers are each weakly bound
to an adjacent dimer through noncovalent Se...Cl bonding interactions. Phenyl
rings within each dimer are oriented in a syn fashion. Density functional theory
(DFT) calculations reveal that the putative anti isomer is within 5 kJ mol-1 of
the experimentally observed form. This structure represents the first additional
polymorph discovered for an organoselenium trihalide compound.https://doi.org/10.1107/S205322961901301
Central retinal artery occlusion and non-arteritic anterior ischemic optic neuropathy associated with an overlap syndrome: a case report
UBM/slit-lamp-photo imaging of pseudoexfoliation deposits in the iridocorneal angle: imaging clues to the genesis of ocular hypertension
This photo essay is aimed at showing slit-lamp photographic views and its ultrasound biomicroscopy (UBM) corollaries of angle deposits in pseudoexfoliation syndrome cases and contributes visual arguments to the hypotheses and explanations of the genesis of ocular hypertension
World caf\ue9 method to engage smart energy-district project partners in assessing urban co-benefits
Urban energy-district projects introduce outstanding technological innovation in buildings and energy systems increasing sustainability in city neighborhoods. Such projects generate additional co-benefits for the city beyond changes in physical elements and development of social and institutional relationships (e.g. local employment, environmental quality, public health, property values, innovation attitude, etc.). Since exceeding main declared goals or not always clearly foreseen in the early project phase, these co-benefits are often not properly understood and considered. However, only their explicit recognition will make possible their inclusion in the assessment of the whole project\u2019s performance. From these considerations, this study faces the issue of engaging project partners in assessing co-benefits in order to consider a broad spectrum of relevant, positive effects in the evaluation process. Group knowledge and group thinking of this complex topic are investigated through the world caf\ue9 method, providing an atmosphere of trust and open discussions among participants. This empirical work lays the foundations to go beyond the mere economic measure as the sole criterion for assessing project effects, also including changes in end-user behavior and intangible asset
Crystal structure and computational study of an oxo-bridged bis-titanium(III) complex
The solid-state structure of the new compound mu-oxido-bis[dichloridotris(tetrahydrofuran-kappa-O)titanium(III)], [Ti2Cl4O(C4H8O)6], at 150 K has been determined. The crystal has monoclinic (C2/c) symmetry and the complex features C2
symmetry about the bridging O atom. Positional disorder is evident in one of the three tetrahydrofuran environments. A post-HartreeâFock computational analysis indicates that the complex has nearly degenerate triplet and singlet spin states, with the former favoured slightly by ca 2 kJ mol-1.Funding for this research was provided by: Natural Sciences and Engineering Research Council of Canada (grant No.RGPIN-2019-06725).https://doi.org/10.1107/S205322962100609
Racial disparity and survival outcomes between African-American and Caucasian American men with penile cancer
Objective: To determine whether there is a survival difference for African-American men (AAM) versus Caucasian American men (CM) with penile squamous cell carcinoma (pSCC), particularly in locally advanced and metastatic cases where disease mortality is highest. Patients and Methods: Using the Florida Cancer Data System, we identified men with pSCC from 2005 to 2013. We compared age, follow-up, stage, race, and treatment type between AAM and CM. We performed Kaplan\u2013Meier analysis for overall survival (OS) between AAM and CM for all stages, and for those with locally advanced and metastatic disease. A multivariable model was developed to determine significant predictors of OS. Results: In all, 653 men (94 AAM and 559 CM) had pSCC and 198 (30%) had locally advanced and/or metastatic disease. A higher proportion of AAM had locally advanced and/or metastatic disease compared to CM (38 [40%] vs 160 [29%], P = 0.03). The median (interquartile range) follow-up for the entire cohort was 12.6 (5.4\u201332.0) months. For all stages, AAM had a significantly lower median OS compared to CM (26 vs 36\ua0months, P = 0.03). For locally advanced and metastatic disease, there was a consistent trend toward disparity in median OS between AAM and CM (17 vs 22\ua0months, P = 0.06). After adjusting for age, stage, grade, and treatment type, AAM with pSCC had a greater likelihood of death compared to CM (hazard ratio 1.64, P = 0.014). Conclusions: AAM have worse OS compared to CM with pSCC and this may partly be due to advanced stage at presentation. Treatment disparity may also contribute to lessened survival in AAM, but we were unable to demonstrate a significant difference in treatment utilisation between the groups
Temporal ocular coherence tomography-measured changes in anterior chamber angle and diurnal intraocular pressure after laser iridoplasty: IMPACT study
Aims: To evaluate temporal change in anterior chamber angle anatomy following argon laser peripheral iridoplasty (ALPI) in eyes with occludable angles postlaser peripheral iridotomy (LPI) compared with control eyes. Additionally, the effect on diurnal intraocular pressure (DIOP) fluctuation (maximum-minimum IOP) was investigated.
Methods: Twenty-two patients with bilateral primary angle closure/suspects with gonioscopically occludable anterior chamber angles following LPI were randomised to receive ALPI (n=11) or no further treatment (n=11). Angle opening distance (AOD), trabecular-iris angle, angle recess area and trabecular-iris space area were measured over eight sections with swept-source anterior segment optical coherence tomography and DIOP was measured pre-LPI and repeated at 3â
months after ALPI (hourly measures).
Results: All angle parameters increased following ALPI. This change was maintained for 3â
months in seven of the eight sections (eg, inferotemporal AOD500 increased by 0.063â
mm, p=0.004 at 1â
day; 0.051â
mm, p=0.029 at 1â
week; 0.059â
mm, p=0.006 at 6â
weeks and 0.056â
mm, p=0.011 at 3â
months). The only exception was in the inferior sector (eg, AOD500 increased by 0.041â
mm, p=0.025 at 1â
day and by 0.029â
mm, p=0.054 at 3â
months). DIOP at 3â
months was significantly reduced (5.04â
mmâ
Hg; ±1.61â
mmâ
Hg) compared with controls (6.61â
mmâ
Hg; ±1.63â
mmâ
Hg). Maximum IOP was significantly greater in the non-ALPI group (1.87â
mmâ
Hg, p=0.026).
Conclusions: ALPI widened all angle sections in eyes that remained occludable post-LPI. Changes were maintained for 3â
months. ALPI decreased DIOP fluctuation in the treated eyes by lowering the maximum IOP value
Exfoliation syndrome: assembling the puzzle pieces
PURPOSE: To summarize various topics and the cutting edge approaches to refine XFS pathogenesis that were discussed at the 21st annual Glaucoma Foundation Think Tank meeting in New York City, Sept. 19-20, 2014.
METHODS: The highlights of three categories of talks on cutting edge research in the field were summarized.
RESULTS: Exfoliation syndrome (XFS) is a systemic disorder with a substantial ocular burden, including high rates of cataract, cataract surgery complications, glaucoma and retinal vein occlusion. New information about XFS is akin to puzzle pieces that do not quite join together to reveal a clear picture regarding how exfoliation material (XFM) forms.
CONCLUSION: Meeting participants concluded that it is unclear how the mild homocysteinemia seen in XFS might contribute to the disarrayed extracellular aggregates characteristic of this syndrome. Lysyl oxidase-like 1 (LOXL1) variants are unequivocally genetic risk factors for XFS but exactly how these variants contribute to the assembly of exfoliation material (XFM) remains unclear. Variants in a new genomic region, CACNA1A associated with XFS, may alter calcium concentrations at the cell surface and facilitate XFM formation but much more work is needed before we can place this new finding in proper context. It is hoped that various animal model and ex vivo systems will emerge that will allow for proper assembly of the puzzle pieces into a coherent picture of XFS pathogenesis. A clear understanding of XFS pathogenesis may lead to 'upstream solutions' to reduce the ocular morbidity produced by XFS
Primary Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure
Background: To investigate the effect of primary phacoemulsification on intraocular pressure (IOP) in patients with acute primary angle-closure (PAC) and coexisting cataract. Methodology: Sixteen eyes of 14 patients with acute PAC received phacoemulsification and intraocular lens implantation as initial management for medically uncontrolled IOP in a retrospective chart review. The effects on IOP, vision, anterior chamber depth (ACD), and number of antiglaucoma medications were evaluated. Principal Findings: The postoperative IOP was reduced in 16 eyes (100%). The mean 6 standard deviation preoperative IOP was 48.81616.83 mm Hg, which decreased postoperatively to 16.46610.67 mm Hg at 1 day, 9.4363.03 mm Hg at 1 week
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