Aplikasi Regresi Partial Least Square Untuk Analisis Hubungan Faktor-faktor Yang Mempengaruhi Indeks Pembangunan Manusia Di Kota YOGYAKARTA

Human Development Index is one of the indicators to measure the success of a region in the field of human development sector. There are several factors that affect Human Development Index, such as life expentancy, the literacy rate, the average length of the school, and the index of purchasing power. The aim in this paper is to analyze the relationship between factors that affect Human Development Index in Yogyakarta using regression analysis. One of the assumptions of classical regression is not going multicollinierity. Multicollinierity cause misinterpretation of regression coefficients with Ordinary Least Square (OLS) method. One method used to overcome multicollinierity is Partial Least Square (PLS). The result of Human Development Index data analysis showed there was a high correlation between the predictor variables or in other words going multicollinierity, so using PLS method, we obtained adjusted R2 of 99.3% Human Development Index variables can be explained by the four predictor variables. By using PLS method, multicollinierity resolved in the problem of violation in the linear regression assumption

Intercoronary Continuity: A Rare Variant of Coronary Circulation

Coronary circulation if significantly diseased usually develop collaterals between the distal portion of the diseased vessel and the normal artery to accomplish flow in vessel distal to the diseased segment. These collaterals can be intracoronary or intercoronary. Coronary collaterals have to be differentiated from intercoronary continuity, which is a very rare variant of coronary circulation usually seen in angiographically normal looking arteries. In our patient, although proximal left anterior descending artery revealed significant lesion but intercoronary continuity was seen between normal right coronary artery and left circumflex artery on angiography

Status of Bone Mineral Density in Patients with Hyperthyroidism

Vitamin D deficiency is widely prevalent in patients with hyperthyroidism along with lower bone mineral density. Against this background, the present study aims to analyze the status of bone mineral density in patients with hyperthyroidism along with age and sex matched controls. 70 consecutive patients and controls were analyzed for thyroid function test, BMD parameters and DEXA scan. The values of BMD parameters were analyzed at the baseline in both patients & control group. The baseline values of vitamin D and PTH of both the groups were 19.24±10.15 Vs 28.38±14.56 and 69.81±57.41Vs 58.53±46.49 respectively. BMD at spine and Hip were -1.38±1.31 Vs -0.26±0.80 and -1.02±1.11 Vs -0.22±0.93 respectively. The BMD of total body was 1.044±0.10 Vs 1.160±0.08. Vitamin D deficiency was found to be prevalent in patients with hyperthyroidism along with significantly reduced BMD compared to controls. The occurrence of osteopenia was higher than osteoporosis in the patient group at both lumbar spine and hip region

Pseudohypoparathyroidism Presenting as Congestive Cardiac Failure

Hypocalcaemia can have a variety of manifestations including cardiovascular changes. Hypocalcemic cardiomyopathy has been reported in hypoparathyroidism and vitamin D deficiency but association of hypocalcemic cardiomyopathy in pseudohypo-parathyroidism has been reported scarcely in literature. We describe here a case of PHP presenting as congestive cardiac failure

Immediate effect of dynamic oscillatory stretching vs. neurodynamic sliding technique on stretch tolerance, popliteal angle range and hamstring flexibility in apparently healthy individuals with hamstring tightness: a pre-post clinical trail

Background: The hamstrings being postural muscles are prone to tightness which leads to muscular imbalances and inefficiency of daily living activities. Hence, the present study aims to compare two competent techniques Dynamic Oscillatory Stretching (DOS)vs. neurodynamic sliding (NDS) technique.Methods: A Total of 60 subjects were recruited (31 males, 29 females). passive 90-90 knee extension test, modified v sit to reach test and NPRS scale were used to evaluate the range, flexibility and stretch tolerance in participants pre intervention and were allotted into Group A (DOS) and Groups B. The subjects were then re-assessed immediately post intervention.Results: The results were obtained using the independent and dependent t-tests. Post intervention results were suggestive of a significant within group result with a p=0.0001 under all the parameters. Subjects in Group a showed a greater increase in the ROM while, Group B showed a better result in flexibility and stretch tolerance.Conclusions: Both the techniques are efficient and can be incorporated in sports rehabilitation to prevent on site injury thereby improving athlete’s performance

Mapping of Environmental Health Risks in Bonetambung Island, Makassar

Bonetambung Island is one of small islands of Spermonde Island Group that had limited access to sea transportations and unavailable environmental sanitation facilities. This study aimed to map environmental health risks to identify the areas of environmental health hazard in Bonetambung Island, Makassar. This study was observational descriptive. Respondents in this study were all households in Bonetambung Island as many as 102 households taken by exchautive sampling method. The result showed that the environmental health hazards in Bonetambung Island were hazard related to the source of clean water (71.1%), domestic wastewater (71.2%) and the ownership of garbage (72.5%). Additionally, some unhealthy behaviors that provided an opportunity for exposure to hazards were not-washing-hand-with-soap behavior (54.2%), open defecation behavior (62.7%), not processing and managing household waste (96.1%), and not-treat-drinking-water behavior (25.5%). So that, the mapping of environmental health risks in Bonetambung Island were very high risk category located in RT 03, high risk category located in RT 02, and low risk category in RT 01.  Keywords: Risk mapping, Environmental health, Small islan

Analisis Konsentrasi Kadmium (Cd) Dan Timbal (Pb) Pada Air Dan Ikan Dari Perairan Sungai Wakak Kendal

Perkembangan industri dan meningkatnya kegiatan manusia, khususnya sepanjang aliran sungai Wakak Kendal saat ini dapat memacu terjadinya pencemaran. Hal ini bisa menjadi berbahaya jika konsentrasi logam berat pada ikan melebihi tingkat nilai ditoleransi , sehingga menjadi berbahaya bagi manusia. Tujuan dari penelitian ini adalah mengetahui konsentrasi kandungan logam berat Cd dan Pb di perairan dan ikan konsumsi di sungai Wakak, Kendal. Informasi ini diharapkan dapat bermanfaat dalam mengevaluasi apakah ikan layak untuk dikonsumsi manusia berdasarkan konsentrasi logam berat dibandingkan dengan standar dari Depkes dan FAO. Penelitian ini dilaksanakan pada bulan September 2014. Sampel air dan ikan dari perairan sungai Wakak diambil dari tiga stasiun dengan masing-masing tiga kali pengulangan kemudian dilakukan uji logam berat menggunakan AAS (Atomic Absorption Spectroscopy). Hasil penelitian menujukan seluruh sampel air tercemar logam berat melebihi nilai baku mutu yang ditetapkan berdasarkan PP. Nomor 82 Tahun 2001. Kontaminasi logam berat Kadmium (Cd) sebesar <0,01 mg/kg sedangkan konsentrasi logam berat Pb terkecil pada ikan adalah 0,61 mg/kg dan tertinggi adalah 2,08 mg/kg maka hasil tersebut menunjukan bahwa telah melebihi nilai ambang batas konsumsi yang ditetapkan berdasarkan SNI 7387:2009 yaitu sebesar 0,3 mg/kg dan berdasarkan Departemen Kesehatan sebesar 2 ppm.The growth of industry and human activities alongside in the river especially in Wakak River Kendal can increase water pollution caused by heavy metal. This could be hazardous if the heavy metal concentration in the fish exceeds the level of tolerable values, thus becoming harmful to humans being. This study aims to assess the concentration of the heavy metals cadmium and lead in the water and fish of Wakak River Kendal. The information is expected to be beneficial in evaluating whether the fish is healthy enough for human consumption or not based on its concentration of heavy metals compare to the standards from Indonesian Health Department and FAO. This research was conducted in September 2014. The heavy metals such as cadmium and lead were analyzed using the AAS(Atomic Absorption Spectroscopy). Water and fish samples were taken from three different sampling points for three time of each. The result shows all of the water samples were contaminated by heavy metal, exceed of the limit value from Indonesian government regulations No. 82 of 2001. Heavy metal contamination of Cadmium ( Cd ) of < 0.01 mg / kg , while the smallest Pb concentrations of heavy metals in fish is 0.61 mg / kg and the highest was 2.08 mg / kg, these results indicate that it has exceeded the threshold value of consumption defined by ISO 7387 : 2009 in the amount of 0.3 mg / kg and by the Ministry of Health is 2 ppm

The Inside Mystery of Jejunal Gastrointestinal Stromal Tumor: A Rare Case Report and Review of the Literature

Gastrointestinal stromal tumors (GISTs) are malignant and rare form of soft tissue sarcoma of the digestive tract. The incidence of gastrointestinal stromal tumors is very low Kramer et al. 2005 Jejunal GISTs are extremely rare. Here we present a rare case of jejunal GIST with unusually large size at presentation. The patient presented with severe abdomen pain, exophytic growth, and dimorphic anemia. Surgical resection of the tumor was carried out, and operative findings revealed a 15 × 10 cm growth, arising from serosal surface of jejunum, at the antimesenteric surface. Diagnosis in this case was made by subjecting the resected specimen to immunohistochemical analysis. In view of large size of the resected tumor, and high-risk histopathological features, imatinib mesylate 400 mg once daily was given as adjuvant chemotherapy. Patient is asymptomatic without any evidence of tumor recurrence after six months of postoperative followup. Imatinib as such is recommended in metastatic, residual or recurrent cases of GISTs or which are surgically not removable; however, recent recommendations suggests the use of imatinib mesylate after radical surgery in high-risk cases, because it has shown a significant decrease in the recurrence rate, and the Food and Drug Administration (FDA) has also approved the use of imatinib as adjuvant therapy after complete resection of localized, primary GIST

Role of Ambulatory and Home Blood Pressure Monitoring in Clinical Practice: A Narrative Review

Hypertension, a common risk factor for cardiovascular disease, is usually diagnosed and treated based on blood pressure readings obtained in the clinic setting. Blood pressure may differ considerably when measured inside versus outside of the clinic setting. Over the past several decades, evidence has accumulated on the following 2 approaches for measuring blood pressure outside of the clinic: ambulatory blood pressure monitoring (ABPM) and home blood pressure monitoring (HBPM). Both of these methods have a stronger association with cardiovascular disease outcomes than clinic blood pressure measurement. Controversy exists about whether ABPM or HBPM is superior for estimating risk for cardiovascular disease and under what circumstances these methods should be used in clinical practice for assessing blood pressure outside of the clinic. This review describes ABPM and HBPM procedures, the blood pressure phenotypic measurements that can be ascertained, and the evidence that supports the use of each approach to measuring blood pressure outside of the clinic. It also describes barriers to the successful implementation of ABPM and HBPM in clinical practice, proposes core competencies for the conduct of these procedures, and highlights important areas for future research