1,681 research outputs found
Natureza de anticorpos precipitantes especĂficos da paracoccidioidomicose (blastomicose Sul-Americana), revelados por contra-imunoeletroforese
Association between serum adiponectin levels and muscular fitness in Portuguese adolescents: LabMed Physical Activity Study
Background and aim: Paradoxically, recent investigations have showed that adiponectin levels are inversely associated with muscle strength. However, to date, there is a lack of knowledge on the relationship between muscular fitness (MF) and adiponectin levels in adolescents. We aimed to examine the independent associations between MF and adiponectin levels in adolescents, controlling for several potential confounders.Methods and results: This is a cross-sectional analysis with 529 Portuguese adolescents aged 12-18 years. A MF score was computed as the mean of the handgrip strength and standing long jump standardized values by age and gender. We measured fasting glucose, insulin, HDL-cholesterol, C-reactive protein and adiponectin. Linear regression analysis showed a significant inverse association between adiponectin (Z-score by age and sex) and MF score, after adjustments for age, sex, pubertal stage, socioeconomic status, adherence to the Mediterranean diet, body mass index, HOMA-IR, HDL-cholesterol, C-reactive protein and cardiorespiratory fitness (unstandardized beta = -0.176; p < 0.005). Analysis of covariance showed a significant difference between the Low MF/Non-overweight group and the High MF/Non-overweight Group (p < 0.05) and between the Low MF/Non-overweight and High MF/Overweight Group (p < 0.05) (F ((5,) (523)) = 2.262, p = 0.047).Conclusion: Adiponectin circulating levels are inversely and independently associated with MF. In non-overweight adolescents, those with high levels of MF presented lower levels of adiponectin compared to those with Low MF. Likewise, overweight adolescents with High MF presented lower levels of serum adiponectin than non-overweight adolescents with Low MF. (C) 2016 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University.This study was supported by FCT grants: BPD/102381/2014 and BD88984/2012; The author Cesar Aparecido Agostinis Sobrinho was given Doctoral scholarship from Brazilian government by CAPES (Coordination of Improvement of Higher Education Personnel) (Proc: 9588-13-2). The Research Centre on Physical Activity Health and Leisure (CIAFEL) is supported by UID/DTP/00617/2013 (FCT). The author Rute Santos has a Discovery Early Career Research Award from the Australian Research Council (DE150101921).The authors gratefully acknowledged the participation of all adolescents and their parents, teachers and schools of the LabMed Study. They also acknowledge the cooperation of volunteer's subjects and the Research Centre in Physical Activity, Health and Leisure (University of Porto) for the sponsoring the LabMed Study.info:eu-repo/semantics/publishedVersio
Associations between anthropometric indicators in early life and low-grade inflammation, insulin resistance and lipid profile in adolescence
Background and AimsThe long-term relations between excessive adiposity in early childhood and unfavourable cardiometabolic profiles in later ages are not yet completely understood. We aimed to assess the associations between birth weight (BW) and BMI from 6 months to 6 years of age, with biomarkers indicative of low-grade inflammation, insulin resistance and lipid profiles in adolescence.Methods and ResultsRetrospective school-based study with 415 Portuguese adolescents (220 girls), mean age of 14.08±1.6 years old. Anthropometric data from birth to 6 years old was extracted from individual child health book records. Actual weight and height were measured and BMI calculated. Participants were classified at each time point as normal weight or overweight according to WHO reference values. Biomarkers were obtained from venous blood samples. Linear regressions were used to explore the associations between the biomarkers and early life anthropometric indicators. From 2 years onwards, BMI associated positively with the inflammatory score and HOMA-IR in adolescence. Children who were overweight/obese from 2 to 6 years of age presented significantly higher inflammatory score and HOMA-IR later in adolescence. TC/HDL ratio was also positively associated with BMI from the age of 5 years onwards. The associations between BMI and cardiometabolic outcomes remained positive in adolescence, with overweight adolescents presenting a higher inflammatory score, HOMA-IR and TC/HDL than normal weight adolescents.ConclusionA high BMI from an early age was consistently associated with worse inflammatory and lipid profiles and insulin resistance in adolescence. No associations were found between BW and the same studied outcomes
Search for coherent elastic neutrino-nucleus scattering at a nuclear reactor with CONNIE 2019 data
The Coherent Neutrino-Nucleus Interaction Experiment (CONNIE) is taking data
at the Angra 2 nuclear reactor with the aim of detecting the coherent elastic
scattering of reactor antineutrinos with silicon nuclei using charge-coupled
devices (CCDs). In 2019 the experiment operated with a hardware binning applied
to the readout stage, leading to lower levels of readout noise and improving
the detection threshold down to 50 eV. The results of the analysis of 2019 data
are reported here, corresponding to the detector array of 8 CCDs with a
fiducial mass of 36.2 g and a total exposure of 2.2 kg-days. The difference
between the reactor-on and reactor-off spectra shows no excess at low energies
and yields upper limits at 95% confidence level for the neutrino interaction
rates. In the lowest-energy range, 50-180 eV, the expected limit stands at 34
(39) times the standard model prediction, while the observed limit is 66 (75)
times the standard model prediction with Sarkis (Chavarria) quenching factors.Comment: 23 pages, 14 figure
Logging Affects Fledgling Sex Ratios and Baseline Corticosterone in a Forest Songbird
Silviculture (logging) creates a disturbance to forested environments. The degree to which forests are modified depends on the logging prescription and forest stand characteristics. In this study we compared the effects of two methods of group-selection (âmoderateâ and âheavyâ) silviculture (GSS) and undisturbed reference stands on stress and offspring sex ratios of a forest interior species, the Ovenbird (Seiurus aurocapilla), in Algonquin Provincial Park, Canada. Blood samples were taken from nestlings for corticosterone and molecular sexing. We found that logging creates a disturbance that is stressful for nestling Ovenbirds, as illustrated by elevated baseline corticosterone in cut sites. Ovenbirds nesting in undisturbed reference forest produce fewer male offspring per brood (proportion maleâ=â30%) while logging with progressively greater forest disturbance, shifted the offspring sex ratio towards males (proportion male: moderateâ=â50%, heavyâ=â70%). If Ovenbirds in undisturbed forests usually produce female-biased broods, then the production of males as a result of logging may disrupt population viability. We recommend a broad examination of nestling sex ratios in response to anthropogenic disturbance to determine the generality of our findings
Recovery of sperm after epididymal refrigeration from domestic cats using ACP-117c and Tris extenders
Linkage disequilibrium and diversity for three genomic regions in Azoreans and mainland Portuguese
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