Towards One Tonne Direct WIMP Detectors: Have we got what it takes?

Experimentally have we got what it takes to pursue the direct observation of WIMP interactions down to sensitivities of a few events /100 kg/year? For a Ge target with a low energy threshold (<20 keVr) this corresponds to a WIMP-nucleon sigma~10^-46 cm^2. A number of recent theoretical papers, making calculations in SUSY-based frameworks, show many (>5) orders of magnitude spread in the possible interaction rates for models consistent with existing Cosmology and Accelerator bounds. Some theorists, but certainly not all, are able to generate models, that lead to interaction rates at the few /kg/day that would be implied by the current DAMA annual modulation signal. All theorists demonstrate models that generate much lower interaction rates. This paper takes an unashamed experimentalist`s view of the issues that arise when looking forward to constructing 1 tonne WIMP detectors.Comment: 12 pages (TeX), 6 figures (eps); IDM2000 3rd International Workshop on the Identification of Dark Matter, York, UK, to be published in proceedings Eds. N. J. C. Spooner and V. Kudryavtsev, World Scientific, Singapore, 2001. Slides available at http://www.hep.ucl.ac.uk/~gaitske

Some model-independent phenomenological consequences of flexible brane worlds

In this work we will review the main properties of brane-world models with low tension. Starting from very general principles, it is possible to obtain an effective action for the relevant degrees of freedom at low energies (branons). Using the cross sections for high-energy processes involving branons, we set bounds on the different parameters appearing in these models. We also show that branons provide a WIMP candidate for dark matter in a natural way. We consider cosmological constraints on its thermal and non-thermal relic abundances. We derive direct detection limits and compare those limits with the preferred parameter region in the case in which the EGRET excess in the diffuse galactic gamma rays is due to dark matter annihilation. Finally we will discuss the constraints coming from the precision tests of the Standard Model and the muon anomalous magnetic moment.Comment: 10 pages, 6 figures. Contribution to the Proceedings of the Second International Conference on Quantum Theories and Renormalization Group in Gravity and Cosmology, IRGAC 2006, Barcelona, 11-15 July, 200

Comment on "Evidence for Neutrinoless Double Beta Decay"

We comment on the recent claim for the experimental observation of neutrinoless double-beta decay. We discuss several limitations in the analysis provided in that paper and conclude that there is no basis for the presented claim.Comment: A comment written to Modern Physics Letters A. 4 pages, no figures. Updated version, accepted for publicatio

Crosstalk between G-protein and Ca2+ pathways switches intracellular cAMP levels

Cyclic adenosine monophosphate and cyclic guanosine monophosphate are universal intracellular messengers whose concentrations are regulated by molecular networks comprised of different isoforms of the synthases adenylate cyclase or guanylate cyclase and the phosphodiesterases which degrade these compounds. In this paper, we employ a systems biology approach to develop mathematical models of these networks that, for the first time, take into account the different biochemical properties of the isoforms involved. To investigate the mechanisms underlying the joint regulation of cAMP and cGMP, we apply our models to analyse the regulation of cilia beat frequency in Paramecium by Ca(2+). Based on our analysis of these models, we propose that the diversity of isoform combinations that occurs in living cells provides an explanation for the huge variety of intracellular processes that are dependent on these networks. The inclusion of both G-protein receptor and Ca(2+)-dependent regulation of AC in our models allows us to propose a new explanation for the switching properties of G-protein subunits involved in nucleotide regulation. Analysis of the models suggests that, depending on whether the G-protein subunit is bound to AC, Ca(2+) can either activate or inhibit AC in a concentration-dependent manner. The resulting analysis provides an explanation for previous experimental results that showed that alterations in Ca(2+) concentrations can either increase or decrease cilia beat frequency over particular Ca(2+) concentration ranges

Determining the Mass of Dark Matter Particles with Direct Detection Experiments

In this article I review two data analysis methods for determining the mass (and eventually the spin-independent cross section on nucleons) of Weakly Interacting Massive Particles with positive signals from direct Dark Matter detection experiments: a maximum likelihood analysis with only one experiment and a model-independent method requiring at least two experiments. Uncertainties and caveats of these methods will also be discussed.Comment: 24 pages, 10 figures, 1 reference added, typos fixed, published version, to appear in the NJP Focus Issue on "Dark Matter and Particle Physics

3D Position Sensitive XeTPC for Dark Matter Search

The technique to realize 3D position sensitivity in a two-phase xenon time projection chamber (XeTPC) for dark matter search is described. Results from a prototype detector (XENON3) are presented.Comment: Presented at the 7th UCLA Symposium on "Sources and Detection of Dark Matter and Dark Energy in the Universe

Tawney and the third way

From the 1920s to the 1950s R. H. Tawney was the most influential socialist thinker in Britain. He articulated an ethical socialism at odds with powerful statist and mechanistic traditions in British socialist thinking. Tawney's work is thus an important antecedent to third way thinking. Tawney's religiously-based critique of the morality of capitalism was combined with a concern for detailed institutional reform, challenging simple dichotomies between public and private ownership. He began a debate about democratizing the enterprise and corporate governance though his efforts fell on stony ground. Conversely, Tawney's moralism informed a whole-hearted condemnation of market forces in tension with both his concern with institutional reform and modern third way thought. Unfortunately, he refused to engage seriously with emergent welfare economics which for many social democrats promised a more nuanced understanding of the limits of market forces. Tawney's legacy is a complex one, whose various elements form a vital part of the intellectual background to current third way thinking