5,747 research outputs found

    A Tight High-Order Entropic Quantum Uncertainty Relation With Applications

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    We derive a new entropic quantum uncertainty relation involving min-entropy. The relation is tight and can be applied in various quantum-cryptographic settings. Protocols for quantum 1-out-of-2 Oblivious Transfer and quantum Bit Commitment are presented and the uncertainty relation is used to prove the security of these protocols in the bounded quantum-storage model according to new strong security definitions. As another application, we consider the realistic setting of Quantum Key Distribution (QKD) against quantum-memory-bounded eavesdroppers. The uncertainty relation allows to prove the security of QKD protocols in this setting while tolerating considerably higher error rates compared to the standard model with unbounded adversaries. For instance, for the six-state protocol with one-way communication, a bit-flip error rate of up to 17% can be tolerated (compared to 13% in the standard model). Our uncertainty relation also yields a lower bound on the min-entropy key uncertainty against known-plaintext attacks when quantum ciphers are composed. Previously, the key uncertainty of these ciphers was only known with respect to Shannon entropy.Comment: 21 pages; editorial changes, additional applicatio

    Control the host cell cycle: Viral regulation of the anaphase-promoting complex

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    Viruses commonly manipulate cell cycle progression to create cellular conditions that are most beneficial to their replication. To accomplish this feat, viruses often target critical cell cycle regulators in order to have maximal effect with minimal input. One such master regulator is the large, multisubunit E3 ubiquitin ligase anaphase-promoting complex (APC) that targets effector proteins for ubiquitination and proteasome degradation. The APC is essential for cells to progress through anaphase, exit from mitosis, and prevent a premature entry into S phase. These far-reaching effects of the APC on the cell cycle are through its ability to target a number of substrates, including securin, cyclin A, cyclin B, thymidine kinase, geminin, and many others. Recent studies have identified several proteins from a number of viruses that can modulate APC activity by different mechanisms, highlighting the potential of the APC in driving viral replication or pathogenesis. Most notably, human cytomegalovirus (HCMV) protein pUL21a was recently identified to disable the APC via a novel mechanism by targeting APC subunits for degradation, both during virus infection and in isolation. Importantly, HCMV lacking both viral APC regulators is significantly attenuated, demonstrating the impact of the APC on a virus infection. Work in this field will likely lead to novel insights into viral replication and pathogenesis and APC function and identify novel antiviral and anticancer targets. Here we review viral mechanisms to regulate the APC, speculate on their roles during infection, and identify questions to be addressed in future studies

    Performance Pay and Multidimensional Sorting - Productivity, Preferences and Gender

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    This paper studies the impact of incentives on worker self-selection in a controlled laboratory experiment. Subjects face the choice between a fixed and a variable payment scheme. Depending on the treatment, the variable payment is a piece rate, a tournament or a revenue-sharing scheme. We find that output is higher in the variable pay schemes (piece rate, tournament, and revenue sharing) compared to the fixed payment scheme. This difference is largely driven by productivity sorting. In addition personal attitudes such as willingness to take risks and relative self-assessment as well as gender affect the sorting decision in a systematic way. Moreover, self-reported effort is significantly higher in all variable pay conditions than in the fixed wage condition. Our lab findings are supported by an additional analysis using data from a large and representative sample. In sum, our findings underline the importance of multi-dimensional sorting, i.e., the tendency for different incentive schemes to systematically attract people with different individual characteristics

    New Soybean Variety - CALLAND - For Southern Iowa

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    Calland will soon provide southern Iowa farmers with an excellent alternative to Wayne and Clark 63 Calland is high yielding and is resistant to phytophthora

    Rampage - New Soybean Variety from Iowa

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    Rampage, a new high yielding soybean variety with maturity similar to Hark, has promise for reducing cost of production and increasing net return per acre. However, it has performed better in tests outside Iowa than within the state. The authos compare Rampage\u27s characteristics and performance with Hark\u27s and discuss its potential in Iowa

    Wirth - New Soybean Variety for Northern Iowa

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    Wirth, a new soybean variety released by the Iowa State University- U.S. Department of Agriculture soybean breeding program, has outyielded current varieties of similar maturity in northern tests. This article discusses its development, performance, adaptation and distribution
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