Connexin 26 Expression in Mammalian Cardiomyocytes

Connexins are a family of membrane-spanning proteins named according to their molecular weight. They are known to form membrane channels mediating cell-cell communication, which play an essential role in the propagation of electrical activity in the heart. Cx26 has been described in a number of tissues but not in the heart, and its mutations are frequently associated with deafness and skin diseases. The aim of this study was to assess the possible Cx26 expression in heart tissues of different mammalian species and to demonstrate its localization at level of cardiomyocytes. Samples of pig, human and rat heart and H9c2 cells were used for our research. Immunohistochemical and molecular biology techniques were employed to test the expression of Cx26. Interestingly, this connexin was found in cardiomyocytes, at level of clusters scattered over the cell cytoplasm but not at level of the intercalated discs where the other cardiac connexins are usually located. Furthermore, the expression of Cx26 in H9c2 myoblast cells increased when they were differentiated into cardiac-like phenotype. To our knowledge, the expression of Cx26 in pig, human and rat has been demonstrated for the first time in the present paper

Union effectiveness: In Search of the Holy Grail

YesThis article revisits the concept of union effectiveness and proposes a conceptual model to inform its study and application. Previous conceptual and empirical work is examined to identify key strengths and weaknesses, and to relate the union effectiveness concept to union renewal and other key concepts. This leads to the proposal of a Goal-System framework that builds and improves on prior research

Work-family balance or greedy organisations?

This paper re-examines the concept of work-family balance by analyzing qualitative data from interviews conducted with Australian senior female staff and managers at a major metropolitan bank and a large, regional hospital. Extant research suggests that managers and staff in senior roles, who have greater autonomy and discretion than other employees, are better able to balance their work and family demands. This paper finds evidence for work-family conflict among participants, who perceive they have "no balance" and must make many personal sacrifices to meet the conflicting demands of work and family. Our findings are confronted with the greedy institutions framework which provides a suitable metaphor to understand the role of organizations in supporting the dual demands of work-family

Homework and CSR: Can homeworkers benefit?

Conference theme: The New World of Work, Organisations and Employmen

Garment homework in Argentina: drawing together the threads of invisible and precarious work

This article explores and applies Kalleberg's concept and dimensions of precarious work in relation to garment homework in Argentina. Although precarious work exists across formal and informal employment, its nature and dimensions are most commonly researched in relation to formal work in developed economies where the loss of standard conditions can be documented. Similarly, homework is most usually discussed as a category of informal work, in the context of developing countries, within which precariousness is one among numerous aspects of adverse job quality. Applying the concept of precariousness enables homework to be assessed systematically against specific labour standards, yielding a more powerful analysis than reference to a general deficit. This may increase our understanding of homework especially with regard to addressing labour standards

Positioning women homeworkers in a global footwear production network: How can homeworkers improve agency, influence and claim rights?

This article analyses the position of women footwear homeworkers, using global production networks as a conceptual lens. Using qualitative data collected in India during 2011 to 2014, it illustrates the asymmetry of power between network actors and attests to the poverty, invisibility and lack of acknowledgement and representation characterising leather footwear homework. It represents leather footwear homeworkers as working from the margins of these networks, with weak links to most other actors in the networks. The paper interrogates how marginalised and informal workers might increase their agency and participation capacity in global production networks, and proposes that this can occur through support and organising undertaken by appropriate non-governmental organisations

Homeworkers organizing for recognition and rights: Can international standards assist them?

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Campaign strategies to develop regulatory mechanisms: Protecting Australian garment homeworkers

Despite key universal characteristics of homework that render it complex and challenging to protect, Australia has a comprehensive suite of regulatory (legislative and non-legislative) mechanisms protecting garment homeworkers. This article proposes that it was the intense and sustained campaigning and mobilisation efforts of the Textile, Clothing and Footwear Union of Australia, undertaken together with the FairWear Campaign and Asian Women at Work, which enabled the emergence and development of these mechanisms. We examine these homework initiatives, applying the lens of responsive regulation theory, to derive implications for global homeworker organisations, shaping their regulatory environments. The article concludes that legislative outcomes alone are insufficient and a combined strategy that encompasses campaigning, legislative reform and social movement strategies that involve the participation of homeworkers are more likely to ensure effective and ongoing homeworker protection

Garment homework in Argentina: Drawing together the threads of informal and precarious work

AbstractThis article explores and applies Kalleberg’s concept and dimensions of precarious work in relation to garment homework in Argentina. Although precarious work exists across formal and informal employment, its nature and dimensions are most commonly researched in relation to formal work in developed economies where the loss of standard conditions can be documented. Similarly, homework is most usually discussed as a category of informal work, in the context of developing countries, within which precariousness is one among numerous aspects of adverse job quality. Applying the concept of precariousness enables homework to be assessed systematically against specific labour standards, yielding a more powerful analysis than reference to a general deficit. This may increase our understanding of homework especially with regard to addressing labour standards.</jats:p