45 research outputs found
Computational prediction of protein interactions related to the invasion of erythrocytes by malarial parasites
N-methylaminoalkoxides of zirconium
N-methylaminoalkoxides of zirconium of the type, Zr(OPri)4-n(O.CHR'.CH2.NR"R')n, where R' = R' = H, R' = Me; R' = H, R' = R' = Me; R' = R' = R' = Me; and n = 1-4, have been synthesized by the reactions of zirconium isopropoxide with aminoalcohols. These are characterized by elemental analyses and IR spectra. Insertion reactions of zirconium aminoalkoxides have been studied for the first time and have been shown to yield interesting derivatives with Zr-N bonds
Fluoro-β-diketone derivatives of titanium
Fluoro-β-diketone derivatives of titanium of the general formula (OR)4-nTi [OC(CF3) = CHCOR']n (R = Et and Pr1; R' = CF3. Ph and C4H3S and n = 1 or 2), have been synthesized by the reaction of titanium alkoxides with fluoro-β-diketones. A few interchange reactions with tertiary butyl or amyl alcohols have also been studied
Even and odd: uranium(IV) complexes with two, four, and six salicylaldiminate ligands with an unusual κ
Low Back Pain, Disability, and Quality of Life One Year following Intradiscal Injection of Autologous Bone Marrow Aspirate Concentrate
Introduction. Degenerative disc disease is a common cause of chronic low back pain. Surgical intervention is an invasive treatment associated with high costs. There is growing interest in regenerative medicine as a less invasive but direct disc treatment for chronic discogenic low back pain. Objective. To evaluate clinical improvement of primary discogenic low back pain with intradiscal injection of autologous bone marrow aspirate concentrate (BMAC). Study Design. Prospective cohort study. Setting. Single, multiphysician center. Patients. 32 adult patients undergoing intradiscal injection of autologous BMAC for the treatment of primary discogenic low back pain. Interventions. Intradiscal injection of autologous BMAC. Main Outcome Measures. Primary outcome measure is visual analog back pain scale (VAS back pain). Secondary outcome measures include ODI, VAS leg pain, and EQ-5D-5L scores. Outcomes were compared from baseline to 1 year. Results. Thirty-two patients (56.3% male) with a mean age of 45.9 years were enrolled, giving 92 treated levels. Mean VAS back and leg pain scores improved from 5.4 to 3.0 (p<0.001) and 2.8 to 1.3 (p=0.005), respectively. Mean ODI scores decreased from 33.5 to 21.1 (p<0.001), and EQ-5D-5L scores improved from 0.69 to 0.78 (p=0.001). Using established MCID values, 59.4% had clinically significant improvement in VAS back pain, 43.8% in VAS leg pain, and 56.3% in ODI scores. Conclusion. Intradiscal injection of autologous BMAC significantly improved low back pain, disability, and quality of life at one year. This study suggests that intradiscal BMAC has the potential to be an effective nonsurgical treatment for chronic discogenic low back pain
Dřevostavba pro rekreační účely
The bachelor thesis deals with the design of a wooden building, which will be used for recreational purposes, and it will also be inhabitable for the whole year. The introductory part focuses on already realized wood buildings for recreational purposes. The architectural design of the recreational building is devised in the theoretical part, including a detailed description of the selected structural system and a description of materials, which will be used for the aforementioned building. For the layers of perimeter construction, there is an assessment of the thermal protection aspect. At the end of the thesis, economic aspects are shown. The thesis also contains a technical report, an accompanying report and basic drawings with added drawings of specified structural details