285 research outputs found
Size induced metal insulator transition in nanostructured Niobium thin films: Intragranular and intergranular contributions
With a reduction in the average grain size in nanostructured films of
elemental Nb, we observe a systematic crossover from metallic to
weakly-insulating behavior. An analysis of the temperature dependence of the
resistivity in the insulating phase clearly indicates the existence of two
distinct activation energies corresponding to inter-granular and intra-granular
mechanisms of transport. While the high temperature behavior is dominated by
grain boundary scattering of the conduction electrons, the effect of
discretization of energy levels due to quantum confinement shows up at low
temperatures. We show that the energy barrier at the grain boundary is
proportional to the width of the largely disordered inter-granular region,
which increases with a decrease in the grain size. For a metal-insulator
transition to occur in nano-Nb due to the opening up of an energy gap at the
grain boundary, the critical grain size is ~ 8nm and the corresponding grain
boundary width is ~ 1.1nm
Non-monotonic size dependence of the elastic modulus of nanocrystalline ZnO embedded in a nanocrystalline silver matrix
We present the first high pressure Raman study on nanocrystalline ZnO films
with different average crystallite sizes. The problem of low Raman signals from
nano sized particles was overcome by forming a nanocomposite of Ag and ZnO
nanoparticles. The presence of the nanodispersed Ag particles leads to a
substantial surface enhancement of the Raman signal from ZnO. We find that the
elastic modulus of nanocrystalline ZnO shows a non-monotonic dependence on the
crystallite size. We suggest that the non-monotonicity arises from an interplay
between the elastic properties of the individual grains and the intergranular
region.Comment: 10 pages, 6 figure
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KIRINYUH (Chromolaena odorata (L.) R. M.) SECARA KLT BIOAUTOGRAFI
The research had conducted the antibacterial activity of ethanol extract of Chromolaena odorata (L.) leaves by TLC Bioautography. It aimed to evaluate the antibacterial activity of the ethanol extract.The ethanol extract of leaves Chromolaena odorata (L.) Â was done by screening at the concentration of 0.1% on Staphylococcus epidermidis, Staphylococcus aureus, Propionibacterium acnes, then test bioautigrafi TLC and identification of chemical components. The results of screening showed that the ethanol extract of 0,1% concentration had an antibacterial activity. Meanwhile, TLC-Bioatography method resulted in 5 active spots with different Rf values 0,1, 0,3, 0,6, 0,8, and 0,9 (Staphylococcus epidermidis), and (Propionibacterium acnes). 4 active spots with Rf values 0,1, 0,3, 0,6, and 0,8 (Staphylococcus aureus) Therefore, the identification of chemical components of ethanol extract contained phenol group compounds.
On-microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiation
Determining the mechanisms by which genes are switched on and off during development is a key aim of current biomedical research. Gene transcription has been widely observed to occur in a discontinuous fashion, with short bursts of activity interspersed with periods of inactivity. It is currently not known if or how this dynamic behaviour changes as mammalian cells differentiate. To investigate this, using an on-microscope analysis, we monitored mouse α-globin transcription in live cells throughout erythropoiesis. We find that changes in the overall levels of α-globin transcription are most closely associated with changes in the fraction of time a gene spends in the active transcriptional state. We identify differences in the patterns of transcriptional bursting throughout differentiation, with maximal transcriptional activity occurring in the mid-phase of differentiation. Early in differentiation, we observe increased fluctuation in transcriptional activity whereas at the peak of gene expression, in early erythroblasts, transcription is relatively stable. Later during differentiation as α-globin expression declines, we again observe more variability in transcription within individual cells. We propose that the observed changes in transcriptional behaviour may reflect changes in the stability of active transcriptional compartments as gene expression is regulated during differentiation
Using XML and XSLT for flexible elicitation of mental-health risk knowledge
Current tools for assessing risks associated with mental-health problems require assessors to make high-level judgements based on clinical experience. This paper describes how new technologies can enhance qualitative research methods to identify lower-level cues underlying these judgements, which can be collected by people without a specialist mental-health background.
Methods and evolving results: Content analysis of interviews with 46 multidisciplinary mental-health experts exposed the cues and their interrelationships, which were represented by a mind map using software that stores maps as XML. All 46 mind maps were integrated into a single XML knowledge structure and analysed by a Lisp program to generate quantitative information about the numbers of experts associated with each part of it. The knowledge was refined by the experts, using software developed in Flash to record their collective views within the XML itself. These views specified how the XML should be transformed by XSLT, a technology for rendering XML, which resulted in a validated hierarchical knowledge structure associating patient cues with risks.
Conclusions: Changing knowledge elicitation requirements were accommodated by flexible transformations of XML data using XSLT, which also facilitated generation of multiple data-gathering tools suiting different assessment circumstances and levels of mental-health knowledge
On the security of consumer wearable devices in the Internet of Things
Miniaturization of computer hardware and the demand for network capable devices has resulted in the emergence of a new class of technology called wearable computing. Wearable devices have many purposes like lifestyle support, health monitoring, fitness monitoring, entertainment, industrial uses, and gaming. Wearable devices are hurriedly being marketed in an attempt to capture an emerging market. Owing to this, some devices do not adequately address the need for security. To enable virtualization and connectivity wearable devices sense and transmit data, therefore it is essential that the device, its data and the user are protected. In this paper the use of novel Integrated Circuit Metric (ICMetric) technology for the provision of security in wearable devices has been suggested. ICMetric technology uses the features of a device to generate an identification which is then used for the provision of cryptographic services. This paper explores how a device ICMetric can be generated by using the accelerometer and gyroscope sensor. Since wearable devices often operate in a group setting the work also focuses on generating a group identification which is then used to deliver services like authentication, confidentiality, secure admission and symmetric key generation. Experiment and simulation results prove that the scheme offers high levels of security without compromising on resource demands
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