A large annotated corpus for learning natural language inference

Understanding entailment and contradiction is fundamental to understanding natural language, and inference about entailment and contradiction is a valuable testing ground for the development of semantic representations. However, machine learning research in this area has been dramatically limited by the lack of large-scale resources. To address this, we introduce the Stanford Natural Language Inference corpus, a new, freely available collection of labeled sentence pairs, written by humans doing a novel grounded task based on image captioning. At 570K pairs, it is two orders of magnitude larger than all other resources of its type. This increase in scale allows lexicalized classifiers to outperform some sophisticated existing entailment models, and it allows a neural network-based model to perform competitively on natural language inference benchmarks for the first time.Comment: To appear at EMNLP 2015. The data will be posted shortly before the conference (the week of 14 Sep) at http://nlp.stanford.edu/projects/snli

INVESTIGATION OF POWER OUTPUT ON A NOVEL BICYCLE DRIVE IN COMPARISON WITH THE COMMON BICYCLE DRIVE

The aim of this study is to check whether a novel bicycle drive allows a higher power output. In order to be able to judge the efficiency of this drive the power output during use of this specific drive was matched with the one of a traditional bicycle drive. Both maximal power output tests and endurance tests with lactate determination where carried out. During the maximal power output tests a power output increase of 5.2% could be measured. During the endurance tests the anaerobe threshold (4 mmol lactate / l blood) at 80 rpm could be raised by 4.17 W, this is equivalent to 2.4%. At four time trials of an amateur cycling club the test riders were 5.3% faster with the new drive over the distance of 14.62 km (with a hairpin bend). This corresponds to a power output increase of 15.9%

Outer structure of the Galactic warp and flare: explaining the Canis Major over-density

(Abridged) We derive the structure of the Galactic stellar Warp and Flare using 2MASS RC and RGB stars, selected at mean heliocentric distances of 3, 7 and 17 kpc. Our results are: (i) a clear stellar warp signature is derived for the 3 selected rings; (ii) the derived stellar warp is consistent (both in amplitude and phase-angle) with that for the Galactic interstellar dust and HI gas; (iii) the Sun seems not to fall on the line of nodes. The stellar warp phase-angle orientation (+15 degrees) is close to the orientation angle of the Galactic bar and this produces an asymmetric warp for the inner rings; (iv) a Northern/Southern warp symmetry is observed only for the ring at 17 kpc; (v) treating a mixture of thin and thick disk populations we trace the disk flaring and derive a constant scale-height (~0.65 kpc) within R(GC)~15 kpc. Further out, the disk flaring increase gradually reaching a mean scale-height of ~1.5 kpc at R(GC)~23 kpc; and (vi) these results provide further robust evidence that there is no disk radial truncation at R(GC)~14 kpc. In the particular case of the Canis Major over-density we confirm its coincidence with the Southern stellar maximum warp occurring near l=240. We present evidence to conclude that all observed parameters (e.g. number density, radial velocities, proper motion etc) of CMa are consistent with it being a normal Milky Way outer-disk population, thereby leaving no justification for a more complex interpretations of its origin. The present analysis does not provide a conclusive test of the structure or origin of the Monoceros Ring. Nevertheless, we show that a warped flared Milky Way contributes significantly at the locations of the Monoceros Ring.Comment: 25 pages, 22 figures, accepted for publication in A&A. A higher resolution pdf file is available at http://wwwuser.oat.ts.astro.it/zaggia/public_html/warp

On the closure problem of the effective stress in the Eulerian-Eulerian and mixture modeling approaches for the simulation of liquid-particle suspensions

© 2019 Author(s). We address the closure problem of the phasic effective stress tensors in the Eulerian-Eulerian and mixture models, considering suspensions of identical particles dispersed in Newtonian liquids. First, after briefly describing the modeling approaches, we review the key mechanisms generating phasic stress and discuss the shortcomings of some constitutive expressions in reproducing important experimental observations. For dilute suspensions, these include the mixture viscosity rise with solid concentration whilst for dense suspensions, the occurrence of particle migration and the change of mixture rheology from Newtonian to non-Newtonian. We then use computational fluid dynamics simulations to compare results based on various stress tensor closures. In a first case study, the simulation results of a laminar flow in a horizontal pipe of a dilute suspension of particles dispersed in a Newtonian liquid are compared to experimental data obtained from the literature. We show that both the Eulerian-Eulerian and mixture models can predict pressure drops accurately but only if they are coupled with suitable experimental closures for the mixture rheology. In a second case study, we simulate the laminar flow of a dense suspension of identical particles dispersed in a Newtonian liquid through an abrupt expansion. We show that the particle concentration profile in the upstream tube, which develops owing to shear-induced particle migration, strongly affects the flow patterns downstream of the expansion. This migration must be modeled via an appropriate closure for the solid effective stress tensor; this allows capturing the sophisticated flow patterns in the expansion section

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

A large library of derivatives based on the scaffold of 2-(benzylsulfinyl)benzoic acid were synthesised and tested as atypical inhibitors against four different isoforms of human carbonic anhydrase (hCA I, II, IX and XII, EC 4.2.1.1). The exploration of the chemical space around the main functional groups led to the discovery of selective hCA IX inhibitors in the micromolar/nanomolar range, thus establishing robust structure-activity relationships within this versatile scaffold. HPLC separation of some selected chiral compounds and biological evaluation of the corresponding enantiomers was performed along with molecular modelling studies on the most active derivatives

Higher Muscle Tissue Oxygenation When Exposed to Hypobaric Hypoxia Than Normobaric Hypoxia

There has been recent debate on the potential difference in physiological response between exposure to simulated altitude (normobaric hypoxia) and terrestrial altitude (hypobaric hypoxia). Purpose: To determine the difference in the physiological response to normobaric and hypobaric hypoxia during exercise. Methods: Eight recreationally active subjects (27 ± 5 y old, 73.1 ± 7.4 kg body weight, 170.6 ± 6.7 cm height, and 19.3 ± 9.2 % body fat) completed incremental cycling exercise to volitional fatigue in three separate environments: normobaric normoxia (NN; 350 m), normobaric hypoxia (NH; simulated 3094 m), and hypobaric hypoxia (HH; 3094 m). Heart rate, blood oxygen saturation, and muscle tissue oxygenation were measured at rest and continuously throughout the exercise trials. Results: Blood oxygen saturation (SpO2) was ~10% higher in NN compared to the two hypoxic conditions (p \u3c 0.001) at rest and all exercise stages, with no difference between NH and HH (p \u3e 0.05). Heart rate was higher at rest in HH (98 ± 13 bpm) compared to NN (83 ± 15 bpm, p = 0.011) and NH (84 ± 14 bpm, p = 0.001) which persisted until 165 watts at which point no difference was observed (p \u3e 0.05). Muscle tissue oxygenation was 17% higher in HH compared to NN and 19% higher than NH throughout exposure (p \u3c 0.05). Conclusion: This data indicates that the hypoxic stress resulting from normobaric and hypobaric hypoxia are not the sameand that hypobaric hypoxia may not result in hypoxia at the level of the tissue

Intra- and extra-cellular excretion of carboxylates

Carboxylates, such as malate and citrate, are widely acknowledged to have a central role in plant metabolism. They are involved in the production of energy and its storage as well as contributing to the cellular osmolyte pool and participating in the regulation of cellular pH. As we discuss here, recent research has demonstrated the functional importance of carboxylate excretion into the soil, apoplast and vacuole, particular with respect to the regulation of stomatal and root function

Relative Frequencies of Blue Stragglers in Galactic Globular Clusters: Constraints for the Formation Mechanisms

We discuss the main properties of the Galactic globular cluster (GC) blue straggler stars (BSS), as inferred from our new catalog containing nearly 3000 BSS. The catalog has been extracted from the photometrically homogeneous V vs. (B-V) color-magnitude diagrams (CMD) of 56 GCs, based on WFPC2 images of their central cores. In our analysis we used consistent relative distances based on the same photometry and calibration. The number of BSS has been normalized to obtain relative frequencies (F_{BSS}) and specific densities (N_S) using different stellar populations extracted from the CMD. The cluster F_{BSS} is significantly smaller than the relative frequency of field BSS. We find a significant anti-correlation between the BSS relative frequency in a cluster and its total absolute luminosity (mass). There is no statistically significant trend between the BSS frequency and the expected collision rate. F_{BSS} does not depend on other cluster parameters, apart from a mild dependence on the central density. PCC clusters act like normal clusters as far as the BSS frequency is concerned. We also show that the BSS luminosity function for the most luminous clusters is significantly different, with a brighter peak and extending to brighter luminosities than in the less luminous clusters. These results imply that the efficiency of BSS production mechanisms and their relative importance vary with the cluster mass.Comment: 12 pages, 3 figures. accepted for publication in ApJ