1,006 research outputs found

    Political Change in Wartime: The Khmer Krahom Revolution in Southern Cambodia 1970-1974

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    An examination of the experience of southern Cambodia from 1971 to 1974 explains how a small but dedicated force was able to impose a revolution on a society without widespread participation of the peasantry

    Integration Challenges for the 1980s: Long Range Plans for School Facilities

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    In 1980 the Milwaukee School Board considered a 1980-90 School Building and Sites Plan which recommends policies for school closings and construction projects for the 1980\u27s. This report by Lois Quinn and Kenneth Robinson of the Metropolitan Integration Research Center discusses the proposals of the School Building and Sites Commission and provides analysis of the three factors which the Commission stated were most important in planning school closings: impact on desegregation, declining enrollments, and budgetary constraints

    Pressure-Sensitive Paint: Effect of Substrate

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    There are numerous ways in which pressure-sensitive paint can be applied to a surface. The choice of substrate and application method can greatly affect the results obtained. The current study examines the different methods of applying pressure-sensitive paint to a surface. One polymer-based and two porous substrates (anodized aluminum and thin-layer chromatography plates) are investigated and compared for luminescent output, pressure sensitivity, temperature sensitivity and photodegradation. Two luminophores [tris-Bathophenanthroline Ruthenium(II) Perchlorate and Platinum-tetrakis (pentafluorophenyl) Porphyrin] will also be compared in all three of the substrates. The results show the applicability of the different substrates and luminophores to different testing environments

    Optic Neuritis and Retinal Ganglion Cell Loss in a Chronic Murine Model of Multiple Sclerosis

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    Multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) are neurodegenerative diseases with characteristic inflammatory demyelination in the central nervous system, including the optic nerve. Neuronal and axonal damage is considered to be the main cause of long-term disability in patients with MS. Neuronal loss, including retinal ganglion cell (RGC) apoptosis in eyes with optic neuritis (ON), also occurs in EAE. However, there is significant variability in the clinical course and level of neuronal damage in MS and EAE. The current studies examine the mechanisms and kinetics of RGC loss in C57/BL6 mice immunized with myelin oligodendrocyte glycoprotein to induce a chronic EAE disease. Clinical progression of EAE was scored daily and vision was assessed by optokinetic responses. At various time points, RGCs were counted and optic nerves were examined for inflammatory cell infiltration. Almost all EAE mice develop ON by day 15 post-immunization; however, RGC loss is delayed in these mice. No RGC loss is detected 25 days post-immunization, whereas RGC numbers in EAE mice significantly and progressively decrease compared to controls from 35 to 50 days post-immunization. The delayed time course of RGC loss is in stark contrast to that reported in relapsing EAE, as well as in rats with chronic EAE. Results suggest that different clinical disease courses of optic nerve inflammation may trigger distinct mechanisms of neuronal damage, or RGCs in different rodent strains may have variable resistance to neuronal degeneration

    An examination of the hydrological system of a sand dam during the dry season leading to water balances

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    To address water scarcity in semi-arid regions, rainfall and runoff need to be captured and stored locally before they are lost to the sea. This can be done using a sand dam which consists of a reinforced wall constructed during the dry season across a seasonal riverbed. However it is unclear whether their main utility is to store water in the sand that is also trapped behind them, or to facilitate aquifer recharge. This paper aims to answer this question by the calculation of a water balance in three sand dams in Kenya to quantify the amount of water transferred between the sand dam and the surrounding aquifer system. The components of the water balance were derived from extensive field monitoring. Water level monitoring in piezometers installed along the length of the sand deposits enabled calculation of the hydraulic gradient and hence the lateral flow between the different reaches of the sand dam. In one sand dam water was gained consistently through the dry season, in one it was lost, and in the third it was lost almost all the time except for the early dry season in the upper part of the trapped sand. In conclusion sand dams should not be treated as isolated water storage structures

    Selection of Potential Mineral Deposits in Southwestern Sinai Using Landsat Imagery

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    Analysis of long branch extraction and long branch shortening.

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    RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.BACKGROUND: Long branch attraction (LBA) is a problem that afflicts both the parsimony and maximum likelihood phylogenetic analysis techniques. Research has shown that parsimony is particularly vulnerable to inferring the wrong tree in Felsenstein topologies. The long branch extraction method is a procedure to detect a data set suffering from this problem so that Maximum Likelihood could be used instead of Maximum Parsimony. RESULTS: The long branch extraction method has been well cited and used by many authors in their analysis but no strong validation has been performed as to its accuracy. We performed such an analysis by an extensive search of the branch length search space under two topologies of six taxa, a Felsenstein-like topology and Farris-like topology. We also examine a long branch shortening method. CONCLUSIONS: The long branch extraction method seems to mask the majority of the search space rendering it ineffective as a detection method of LBA. A proposed alternative, the long branch shortening method, is also ineffective in predicting long branch attraction for all tree topologies
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