741 research outputs found
Approximating the inspiral of test bodies into Kerr black holes
We present a new approximate method for constructing gravitational radiation
driven inspirals of test-bodies orbiting Kerr black holes. Such orbits can be
fully described by a semi-latus rectum , an eccentricity , and an
inclination angle ; or, by an energy , an angular momentum component
, and a third constant . Our scheme uses expressions that are exact
(within an adiabatic approximation) for the rates of change (,
, ) as linear combinations of the fluxes (,
, ), but uses quadrupole-order formulae for these fluxes.
This scheme thus encodes the exact orbital dynamics, augmenting it with
approximate radiation reaction. Comparing inspiral trajectories, we find that
this approximation agrees well with numerical results for the special cases of
eccentric equatorial and circular inclined orbits, far more accurate than
corresponding weak-field formulae for (, , ). We
use this technique to study the inspiral of a test-body in inclined, eccentric
Kerr orbits. Our results should be useful tools for constructing approximate
waveforms that can be used to study data analysis problems for the future LISA
gravitational-wave observatory, in lieu of waveforms from more rigorous
techniques that are currently under development.Comment: 15 pages, 5 figures, submitted to PR
Nearly horizon skimming orbits of Kerr black holes
An unusual set of orbits about extreme Kerr black holes resides at the
Boyer-Lindquist radius , the coordinate of the hole's event horizon.
These ``horizon skimming'' orbits have the property that their angular momentum
{\it increases} with inclination angle, opposite to the familiar behavior
one encounters at larger radius. In this paper, I show that this behavior is
characteristic of a larger family of orbits, the ``nearly horizon skimming''
(NHS) orbits. NHS orbits exist in the very strong field of any black hole with
spin a\agt 0.952412M. Their unusual behavior is due to the locking of
particle motion near the event horizon to the hole's spin, and is therefore a
signature of the Kerr metric's extreme strong field. An observational hallmark
of NHS orbits is that a small body spiraling into a Kerr black hole due to
gravitational-wave emission will be driven into orbits of progressively smaller
inclination angle, toward the equator. This is in contrast to the ``normal''
behavior. For circular orbits, the change in inclination is very small, and
unlikely to be of observational importance. I argue that the change in
inclination may be considerably larger when one considers the evolution of
inclined eccentric orbits. If this proves correct, then the gravitational waves
produced by evolution through the NHS regime may constitute a very interesting
and important probe of the strong-field nature of rotating black holes.Comment: 9 pages, 5 figures, accepted for publication in PR
Use of Mobile Learning by Resident Physicians in Botswana
With the growth of mobile health in recent years, learning through the use of mobile devices (mobile learning [mLearning]) has gained recognition as a potential method for increasing healthcare providers\u27 access to medical information and resources in resource-limited settings. In partnership with the University of Botswana School of Medicine (SOM), we have been exploring the role of smartphone-based mLearning with resident (physicians in specialty training) education. The SOM, which admitted its first class of medical students and residents in 2009, is committed to providing high-level on-site educational resources for resident physicians, even when practicing in remote locations. Seven residents were trained to use an Android-based myTouch 3G smartphone equipped with data-enabled subscriber identity module (SIM) cards and built-in camera. Phones contained locally loaded point-of-care and drug information applications, a telemedicine application that allows for the submission of cases to local mentors, and e-mail/Web access. Surveys were administered at 4 weeks and 8 weeks following distribution of phones. We found that smartphones loaded with point-of-care tools are effectively utilized by resident physicians in resource-limited settings, both for accessing point-of-care medical information at the bedside and engaging in self-directed learning at home
Gravitational Waves from a Compact Star in a Circular, Inspiral Orbit, in the Equatorial Plane of a Massive, Spinning Black Hole, as Observed by LISA
Results are presented from high-precision computations of the orbital
evolution and emitted gravitational waves for a stellar-mass object spiraling
into a massive black hole in a slowly shrinking, circular, equatorial orbit.
The focus of these computations is inspiral near the innermost stable circular
orbit (isco)---more particularly, on orbits for which the angular velocity
Omega is 0.03 < Omega/Omega_{isco} < 1. The computations are based on the
Teukolsky-Sasaki-Nakamura formalism, and the results are tabulated in a set of
functions that are of order unity and represent relativistic corrections to
low-orbital-velocity formulas. These tables can form a foundation for future
design studies for the LISA space-based gravitational-wave mission. A first
survey of applications to LISA is presented: Signal to noise ratios S/N are
computed and graphed as functions of the time-evolving gravitational-wave
frequency for representative values of the hole's mass M and spin a and the
inspiraling object's mass \mu, with the distance to Earth chosen to be r_o = 1
Gpc. These S/N's show a very strong dependence on the black-hole spin, as well
as on M and \mu. A comparison with predicted event rates shows strong promise
for detecting these waves, but not beyond about 1Gpc if the inspiraling object
is a white dwarf or neutron star. This argues for a modest lowering of LISA's
noise floor. A brief discussion is given of the prospects for extracting
information from the observed wavesComment: Physical Review D, in press; 21 pages, 9 figures, 10 tables it is
present in the RevTeX fil
Symptom Clusters in Acute Myocardial Infarction: A Secondary Data Analysis
Background: Early recognition of acute myocardial infarction (AMI) symptoms and reduced time to treatment may reduce morbidity and mortality. People having AMI experience a constellation of symptoms, but the common constellations or clusters of symptoms have yet to be identified. Objectives: To identify clusters of symptoms that represent AMI. Methods: This was a secondary data analysis of nine descriptive, cross-sectional studies that included data from 1,073 people having AMI in the United States and England. Data were analyzed using latent class cluster analysis, an atheoretical method that uses only information contained in the data. Results: Five distinct clusters of symptoms were identified. Age, race, and sex were statistically significant in predicting cluster membership. None of the symptom clusters described in this analysis included all of the symptoms that are considered typical. In one cluster, subjects had only a moderate to low probability of experiencing any of the symptoms analyzed. Discussion: Symptoms of AMI occur in clusters, and these clusters vary among persons. None of the clusters identified in this study included all of the symptoms that are included typically as symptoms of AMI (chest discomfort, diaphoresis, shortness of breath, nausea, and lightheadedness). These AMI symptom clusters must be communicated clearly to the public in a way that will assist them in assessing their symptoms more efficiently and will guide their treatment-seeking behavior. Symptom clusters for AMI must also be communicated to the professional community in a way that will facilitate assessment and rapid intervention for AMI
Site-Selective Aliphatic C–H Chlorination Using N -Chloroamides Enables a Synthesis of Chlorolissoclimide
Methods for the practical, intermolecular functionalization of aliphatic C-H bonds remain a paramount goal of organic synthesis. Free radical alkane chlorination is an important industrial process for the production of small molecule chloroalkanes from simple hydrocarbons, yet applications to fine chemical synthesis are rare. Herein, we report a site-selective chlorination of aliphatic C-H bonds using readily available N-chloroamides and apply this transformation to a synthesis of chlorolissoclimide, a potently cytotoxic labdane diterpenoid. These reactions deliver alkyl chlorides in useful chemical yields with substrate as the limiting reagent. Notably, this approach tolerates substrate unsaturation that normally poses major challenges in chemoselective, aliphatic C-H functionalization. The sterically and electronically dictated site selectivities of the C-H chlorination are among the most selective alkane functionalizations known, providing a unique tool for chemical synthesis. The short synthesis of chlorolissoclimide features a high yielding, gram-scale radical C-H chlorination of sclareolide and a three-step/two-pot process for the introduction of the β-hydroxysuccinimide that is salient to all the lissoclimides and haterumaimides. Preliminary assays indicate that chlorolissoclimide and analogues are moderately active against aggressive melanoma and prostate cancer cell lines
Carbon Dioxide Fluxes Reflect Plant Zonation and Belowground Biomass in a Coastal Marsh
Coastal wetlands are major global carbon sinks; however, they are heterogeneous and dynamic ecosystems. To characterize spatial and temporal variability in a New England salt marsh, greenhouse gas (GHG) fluxes were compared among major plant-defined zones during growing seasons. Carbon dioxide (CO2) and methane (CH4) fluxes were compared in two mensurative experiments during summer months (2012–2014) that included low marsh (Spartina alterniflora), high marsh (Distichlis spicata and Juncus gerardiidominated), invasive Phragmites australis zones, and unvegetated ponds. Day- and nighttime fluxes were also contrasted in the native marsh zones. N2O fluxes were measured in parallel with CO2 and CH4 fluxes, but were not found to be significant. To test the relationships of CO2 and CH4 fluxes with several native plant metrics, a multivariate nonlinear model was used. Invasive P. australis zones (−7 to −15 μmol CO2·m−2·s−1) and S. alterniflora low marsh zones (up to −14 μmol CO2·m−2·s−1) displayed highest average CO2 uptake rates, while those in the native high marsh zone (less than −2 μmol CO2·m−2·s−1) were much lower. Unvegetated ponds were typically small sources of CO2 to the atmosphere (\u3c0.5 μmol CO2·m−2·s−1). Nighttime emissions of CO2 averaged only 35% of daytime uptake in the low marsh zone, but they exceeded daytime CO2 uptake by up to threefold in the native high marsh zone. Based on modeling, belowground biomass was the plant metric most strongly correlated with CO2 fluxes in native marsh zones, while none of the plant variables correlated significantly with CH4 fluxes. Methane fluxes did not vary between day and night and did not significantly offset CO2 uptake in any vegetated marsh zones based on sustained global warming potential calculations. These findings suggest that attention to spatial zonation as well as expanded measurements and modeling of GHG emissions across greater temporal scales will help to improve accuracy of carbon accounting in coastal marshe
Carbon Dioxide Fluxes Reflect Plant Zonation and Belowground Biomass in a Coastal Marsh
Coastal wetlands are major global carbon sinks; however, they are heterogeneous and dynamic ecosystems. To characterize spatial and temporal variability in a New England salt marsh, greenhouse gas (GHG) fluxes were compared among major plant-defined zones during growing seasons. Carbon dioxide (CO2) and methane (CH4) fluxes were compared in two mensurative experiments during summer months (2012–2014) that included low marsh (Spartina alterniflora), high marsh (Distichlis spicata and Juncus gerardiidominated), invasive Phragmites australis zones, and unvegetated ponds. Day- and nighttime fluxes were also contrasted in the native marsh zones. N2O fluxes were measured in parallel with CO2 and CH4 fluxes, but were not found to be significant. To test the relationships of CO2 and CH4 fluxes with several native plant metrics, a multivariate nonlinear model was used. Invasive P. australis zones (−7 to −15 μmol CO2·m−2·s−1) and S. alterniflora low marsh zones (up to −14 μmol CO2·m−2·s−1) displayed highest average CO2 uptake rates, while those in the native high marsh zone (less than −2 μmol CO2·m−2·s−1) were much lower. Unvegetated ponds were typically small sources of CO2 to the atmosphere (\u3c0.5 μmol CO2·m−2·s−1). Nighttime emissions of CO2 averaged only 35% of daytime uptake in the low marsh zone, but they exceeded daytime CO2 uptake by up to threefold in the native high marsh zone. Based on modeling, belowground biomass was the plant metric most strongly correlated with CO2 fluxes in native marsh zones, while none of the plant variables correlated significantly with CH4 fluxes. Methane fluxes did not vary between day and night and did not significantly offset CO2 uptake in any vegetated marsh zones based on sustained global warming potential calculations. These findings suggest that attention to spatial zonation as well as expanded measurements and modeling of GHG emissions across greater temporal scales will help to improve accuracy of carbon accounting in coastal marshe
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