87 research outputs found
Buckling instability causes inertial thrust for spherical swimmers at all scales
Microswimmers, and among them aspirant microrobots, generally have to cope
with flows where viscous forces are dominant, characterized by a low Reynolds
number (). This implies constraints on the possible sequences of body
motion, which have to be nonreciprocal. Furthermore, the presence of a strong
drag limits the range of resulting velocities. Here, we propose a swimming
mechanism, which uses the buckling instability triggered by pressure waves to
propel a spherical, hollow shell. With a macroscopic experimental model, we
show that a net displacement is produced at all regimes. An optimal
displacement caused by non-trivial history effects is reached at intermediate
. We show that, due to the fast activation induced by the instability, this
regime is reachable by microscopic shells. The rapid dynamics would also allow
high frequency excitation with standard traveling ultrasonic waves. Scale
considerations predict a swimming velocity of order 1 cm/s for a
remote-controlled microrobot, a suitable value for biological applications such
as drug delivery.Comment: To appear in Phys. Rev. Lett See demonstration movie on
https://www.youtube.com/watch?v=cEXMsFwEqs
Simulations of viscous shape relaxation in shuffled foam clusters
We simulate the shape relaxation of foam clusters and compare them with the
time exponential expected for Newtonian fluid. Using two-dimensional Potts
Model simulations, we artificially create holes in a foam cluster and shuffle
it by applying shear strain cycles. We reproduce the experimentally observed
time exponential relaxation of cavity shapes in the foam as a function of the
number of strain steps. The cavity rounding up results from local rearrangement
of bubbles, due to the conjunction of both a large applied strain and local
bubble wall fluctuations
Topological and geometrical disorder correlate robustly in two-dimensional foams
A 2D foam can be characterised by its distribution of bubble areas, and of
number of sides. Both distributions have an average and a width (standard
deviation). There are therefore at least two very different ways to
characterise the disorder. The former is a geometrical measurement, while the
latter is purely topological. We discuss the common points and differences
between both quantities. We measure them in a foam which is sheared, so that
bubbles move past each other and the foam is "shuffled" (a notion we discuss).
Both quantities are strongly correlated; in this case (only) it thus becomes
sufficient to use either one or the other to characterize the foam disorder. We
suggest applications to the analysis of other systems, including biological
tissues
Volume-controlled buckling of thin elastic shells: Application to crusts formed on evaporating partially-wetted droplets
Motivated by the buckling of glassy crusts formed on evaporating droplets of
polymer and colloid solutions, we numerically model the deformation and
buckling of spherical elastic caps controlled by varying the volume between the
shell and the substrate. This volume constraint mimics the incompressibility of
the unevaporated solvent. Discontinuous buckling is found to occur for
sufficiently thin and/or large contact angle shells, and robustly takes the
form of a single circular region near the boundary that `snaps' to an inverted
shape, in contrast to externally pressurised shells. Scaling theory for shallow
shells is shown to well approximate the critical buckling volume, the
subsequent enlargement of the inverted region and the contact line force.Comment: 7 pages in J. Phys. Cond. Mat. spec; 4 figs (2 low-quality to reach
LANL's over-restrictive size limits; ask for high-detailed versions if
required
Two-dimensional flow of foam around an obstacle: force measurements
A Stokes experiment for foams is proposed. It consists in a two-dimensional
flow of a foam, confined between a water subphase and a top plate, around a
fixed circular obstacle. We present systematic measurements of the drag exerted
by the flowing foam on the obstacle, \emph{versus} various separately
controlled parameters: flow rate, bubble volume, bulk viscosity, obstacle size,
shape and boundary conditions. We separate the drag into two contributions, an
elastic one (yield drag) at vanishing flow rate, and a fluid one (viscous
coefficient) increasing with flow rate. We quantify the influence of each
control parameter on the drag. The results exhibit in particular a power-law
dependence of the drag as a function of the bulk viscosity and the flow rate
with two different exponents. Moreover, we show that the drag decreases with
bubble size, and increases proportionally to the obstacle size. We quantify the
effect of shape through a dimensioned drag coefficient, and we show that the
effect of boundary conditions is small.Comment: 26 pages, 13 figures, resubmitted version to Phys. Rev.
Anisotropic colloids through non-trivial buckling
We present a study on buckling of colloidal particles, including
experimental, theoretical and numerical developments. Oil-filled thin shells
prepared by emulsion templating show buckling in mixtures of water and ethanol,
due to dissolution of the core in the external medium. This leads to
conformations with a single depression, either axisymmetric or polygonal
depending on the geometrical features of the shells. These conformations could
be theoretically and/or numerically reproduced in a model of homogeneous
spherical thin shells with bending and stretching elasticity, submitted to an
isotropic external pressure.Comment: submitted to EPJ
Statistical Mechanics of Two-dimensional Foams
The methods of statistical mechanics are applied to two-dimensional foams
under macroscopic agitation. A new variable -- the total cell curvature -- is
introduced, which plays the role of energy in conventional statistical
thermodynamics. The probability distribution of the number of sides for a cell
of given area is derived. This expression allows to correlate the distribution
of sides ("topological disorder") to the distribution of sizes ("geometrical
disorder") in a foam. The model predictions agree well with available
experimental data
Modifying effect of dual antiplatelet therapy on incidence of stent thrombosis according to implanted drug-eluting stent type
Aim To investigate the putative modifying effect of dual antiplatelet therapy (DAPT) use on the incidence of stent thrombosis at 3 years in patients randomized to Endeavor zotarolimus-eluting stent (E-ZES) or Cypher sirolimus-eluting stent (C-SES). Methods and results Of 8709 patients in PROTECT, 4357 were randomized to E-ZES and 4352 to C-SES. Aspirin was to be given indefinitely, and clopidogrel/ticlopidine for ≥3 months or up to 12 months after implantation. Main outcome measures were definite or probable stent thrombosis at 3 years. Multivariable Cox regression analysis was applied, with stent type, DAPT, and their interaction as the main outcome determinants. Dual antiplatelet therapy adherence remained the same in the E-ZES and C-SES groups (79.6% at 1 year, 32.8% at 2 years, and 21.6% at 3 years). We observed a statistically significant (P = 0.0052) heterogeneity in treatment effect of stent type in relation to DAPT. In the absence of DAPT, stent thrombosis was lower with E-ZES vs. C-SES (adjusted hazard ratio 0.38, 95% confidence interval 0.19, 0.75; P = 0.0056). In the presence of DAPT, no difference was found (1.18; 0.79, 1.77; P = 0.43). Conclusion A strong interaction was observed between drug-eluting stent type and DAPT use, most likely prompted by the vascular healing response induced by the implanted DES system. These results suggest that the incidence of stent thrombosis in DES trials should not be evaluated independently of DAPT use, and the optimal duration of DAPT will likely depend upon stent type (Clinicaltrials.gov number NCT00476957
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