145 research outputs found

    Oscillation criteria for third-order neutral differential equations with continuously distributed delay

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    AbstractThe purpose of this paper is to study the oscillation of a certain class of third-order neutral differential equations with continuously distributed delay. By using a generalized Riccati transformation and integral averaging technique, we establish some new sufficient conditions which ensure that every solution of this equation oscillates or converges to zero

    Developing an Enhanced Short-Range Railroad Track Condition Prediction Model for Optimal Maintenance Scheduling

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    As railroad infrastructure becomes older and older and rail transportation is developing towards higher speed and heavier axle, the risk to safe rail transport and the expenses for railroad maintenance are increasing. The railroad infrastructure deterioration (prediction) model is vital to reducing the risk and the expenses. A short-range track condition prediction method was developed in our previous research on railroad track deterioration analysis. It is intended to provide track maintenance managers with two or three months of track condition in advance to schedule track maintenance activities more smartly. Recent comparison analyses on track geometrical exceptions calculated from track condition measured with track geometry cars and those predicted by the method showed that the method fails to provide reliable condition for some analysis sections. This paper presented the enhancement to the method. One year of track geometry data for the Jiulong-Beijing railroad from track geometry cars was used to conduct error analyses and comparison analyses. Analysis results imply that the enhanced model is robust to make reliable predictions. Our in-process work on applying those predicted conditions for optimal track maintenance scheduling is discussed in brief as well

    New Oscillatory Behavior of Third-Order Nonlinear Delay Dynamic Equations on Time Scales

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    A class of third-order nonlinear delay dynamic equations on time scales is studied. By using the generalized Riccati transformation and the inequality technique, four new sufficient conditions which ensure that every solution is oscillatory or converges to zero are established. The results obtained essentially improve earlier ones. Some examples are considered to illustrate the main results

    Low-Cost Flexible Nano-Sulfide/Carbon Composite Counter Electrode for Quantum-Dot-Sensitized Solar Cell

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    Cu2S nanocrystal particles were in situ deposited on graphite paper to prepare nano-sulfide/carbon composite counter electrode for CdS/CdSe quantum-dot-sensitized solar cell (QDSC). By optimization of deposition time, photovoltaic conversion efficiency up to 3.08% was obtained. In the meantime, this composite counter electrode was superior to the commonly used Pt, Au and carbon counter electrodes. Electrochemical impedance spectra further confirmed that low charge transfer resistance at counter electrode/electrolyte interface was responsible for this, implied the potential application of this composite counter electrode in high-efficiency QDSC

    Morphological diversity of single neurons in molecularly defined cell types.

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    Dendritic and axonal morphology reflects the input and output of neurons and is a defining feature of neuronal types1,2, yet our knowledge of its diversity remains limited. Here, to systematically examine complete single-neuron morphologies on a brain-wide scale, we established a pipeline encompassing sparse labelling, whole-brain imaging, reconstruction, registration and analysis. We fully reconstructed 1,741 neurons from cortex, claustrum, thalamus, striatum and other brain regions in mice. We identified 11 major projection neuron types with distinct morphological features and corresponding transcriptomic identities. Extensive projectional diversity was found within each of these major types, on the basis of which some types were clustered into more refined subtypes. This diversity follows a set of generalizable principles that govern long-range axonal projections at different levels, including molecular correspondence, divergent or convergent projection, axon termination pattern, regional specificity, topography, and individual cell variability. Although clear concordance with transcriptomic profiles is evident at the level of major projection type, fine-grained morphological diversity often does not readily correlate with transcriptomic subtypes derived from unsupervised clustering, highlighting the need for single-cell cross-modality studies. Overall, our study demonstrates the crucial need for quantitative description of complete single-cell anatomy in cell-type classification, as single-cell morphological diversity reveals a plethora of ways in which different cell types and their individual members may contribute to the configuration and function of their respective circuits

    Cellular anatomy of the mouse primary motor cortex.

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    An essential step toward understanding brain function is to establish a structural framework with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and systems can be integrated and interpreted1. Here, as part of the collaborative Brain Initiative Cell Census Network (BICCN), we derive a comprehensive cell type-based anatomical description of one exemplar brain structure, the mouse primary motor cortex, upper limb area (MOp-ul). Using genetic and viral labelling, barcoded anatomy resolved by sequencing, single-neuron reconstruction, whole-brain imaging and cloud-based neuroinformatics tools, we delineated the MOp-ul in 3D and refined its sublaminar organization. We defined around two dozen projection neuron types in the MOp-ul and derived an input-output wiring diagram, which will facilitate future analyses of motor control circuitry across molecular, cellular and system levels. This work provides a roadmap towards a comprehensive cellular-resolution description of mammalian brain architecture
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