On the blow-up structure for the generalized periodic Camassa-Holm and Degasperis-Procesi equations

Considered herein are the generalized Camassa-Holm and Degasperis-Procesi equations in the spatially periodic setting. The precise blow-up scenarios of strong solutions are derived for both of equations. Several conditions on the initial data guaranteeing the development of singularities in finite time for strong solutions of these two equations are established. The exact blow-up rates are also determined. Finally, geometric descriptions of these two integrable equations from non-stretching invariant curve flows in centro-equiaffine geometries, pseudo-spherical surfaces and affine surfaces are given.Comment: 26 page

A unified theory of calcium alternans in ventricular myocytes.

Intracellular calcium (Ca2+) alternans is a dynamical phenomenon in ventricular myocytes, which is linked to the genesis of lethal arrhythmias. Iterated map models of intracellular Ca2+ cycling dynamics in ventricular myocytes under periodic pacing have been developed to study the mechanisms of Ca2+ alternans. Two mechanisms of Ca2+ alternans have been demonstrated in these models: one relies mainly on fractional sarcoplasmic reticulum Ca2+ release and uptake, and the other on refractoriness and other properties of Ca2+ sparks. Each of the two mechanisms can partially explain the experimental observations, but both have their inconsistencies with the experimental results. Here we developed an iterated map model that is composed of two coupled iterated maps, which unifies the two mechanisms into a single cohesive mathematical framework. The unified theory can consistently explain the seemingly contradictory experimental observations and shows that the two mechanisms work synergistically to promote Ca2+ alternans. Predictions of the theory were examined in a physiologically-detailed spatial Ca2+ cycling model of ventricular myocytes