STUDY ON THE INTERACTION BETWEEN FORMWORK SHORING SYSTEMS AND RC STRUCTURES IN A HIGH-RISE BUILDING DURING CONSTRUCTION 2

In the construction process of high-rise building structure, the formwork temporary supports and the concrete structure are considered as a whole. Quantifying the load under the template supports can provide a better reference for the design of the template supports. In order to study the load transfer law between formwork support scaffolds and multi-storey structure, through the installation of sensors at the bottom of formwork supports and the floor slab, the load transfer law of the 3 adjacent formwork supports were monitored for a long time during the construction of high-rise buildings via the high-frequency wireless transmission systems. The main conclusions are as follows: (1) The monitoring data shows that the most unfavourable load occurs when concrete is poured into the upper story, about 1.9 times the axial force generated when concrete is poured into the test floor. (2) The monitoring data has a similar shape which is summed up as an ideal curve of change, 3 times of peak value, 3 times of decline and 1 time of sudden drop. (3)The transfer ratio of load accounts for about 57% ~ 69% of a total load of fresh concrete. (4) Considering the fluid-plastic state of concrete, a correction factor of 1.22 for vertical pole axial force is proposed, and the deviation between the modified simulated value and the measured value is less than 3%

Effect of Nano-CaCO3 on the Mechanical Properties and Durability of Concrete Incorporating Fly Ash

Concrete mixtures consisting of nanomaterials and fly ash have been shown to be effective for improving the performance of concrete. This study investigates the combined effects of nano-CaCO3 and fly ash on the mechanical properties and durability of concrete; the mix proportion is optimized through orthogonal experiments. In the first phase, nine concrete mixtures were prepared with three water-to-binder ratios (0.4, 0.5, and 0.6), three fly ash contents (15%, 20%, and 25% replacement of the cement weight), and three nano-CaCO3 contents (1%, 2%, and 3% replacement of the cement weight). Based on the orthogonal analysis, the optimal concrete mix proportion was determined as a water-to-binder ratio of 0.4, 20% fly ash, and 1% nano-CaCO3. In the second phase, further investigations were carried out to examine the superiority of the optimal concrete and evaluate the synergistic effect of nano-CaCO3 and fly ash. The results showed that nano-CaCO3 contributed to increasing the compressive strength of fly ash concrete at the early ages, but its effect was quite limited at later ages. Furthermore, the scanning electron microscopy analysis revealed that the seeding effect, filling effect, and pozzolanic effect were the primary mechanisms for the improvement of concrete performance

Analysis of bronchoscopy characteristics for 729 female patients with lung cancer

Background and objective The aim of this article is to study features of the bronchoscopy signs in female lung cancer patients. Methods The bronchoscopy data of 729 female lung cancer patients enrolled between January 1994 and June 2007 was analyzed, retrospectively. Results Most of the patients were middle-aged female (57.0%), then were the elderly (28.5%), and the youth composed much lower (14.0%). The most common histopathology was adenocarcinoma (42.8%), followed by squamous cell carcinoma (23.9%) and small cell carcinoma (19.2%), and all of them increased in the past few years. The female lung cancers were more in the right lung (P<0.05), and the upper lobes (P<0.05). Among 729 female lung cancer patients, 92.0% had apparent signs. Most of adenocarcinoma had infiltrative changes (P<0.05), but most of squamous cell carcinoma and small cell carcinoma had proliferative changes (P<0.05). The most common sing of bronchoscopy in patients with atelectasis was proliferative changes (P<0.05), but the most common sings of bronchoscopy in patients with pleural effusion was infiltrative changes (P<0.05). Conclusion This study suggests brochoscopy is an important approach in diagnosis of female lung cancer. Paying more attention to the lung cancer of female patients and examining with bronchoscopy would be helpful for earlier diagnosis

Strength Correlation and Prediction of Engineered Cementitious Composites with Microwave Properties

This paper presents the results of microwave and mechanical measurements of engineered cementitious composites (ECCs) using a nondestructive microwave near-field detecting technique. The objective of this research is to investigate the correlations between effective conductance and compressive strength of ECCs at various curing ages under the influence of different initial water contents. Parallel measurements and regression analysis on compressive strength and microwave conductance were undertaken. It is shown that the strength evolution of ECCs can be accurately modeled and predicted by using microwave conductance at the early ages using bi-exponential functions. Compressive strength grows as a function of decreasing effective conductance, whereas the regression coefficients of the correlation models have a linear variation with water-to-binder ratios. These findings have highlighted the effectiveness of the microwave technique in detecting the variation of liquid phase morphology and pore structure

Dielectric characterization of Chinese standard concrete for compressive strength evaluation

Dielectric characterization of concrete is essential for the wireless structural health monitoring (SHM) of concrete structures. Guo Biao (GB) concrete refers to the concrete mixed and cast in accordance with the Chinese standard. Currently, China is the largest producer and consumer of concrete in the world. However, minimal attention has been paid to the dielectric properties of GB concrete. This paper presents the results of the dielectric constant of GB concrete, where three regression models have been used to present the measurement data from 10 MHz to 6 GHz. The objective is to provide a data set of nominal values of the dielectric constant for ordinary GB concrete. The final goal is to facilitate a compressive strength evaluation via the measured dielectric constant. Measurements of the dielectric constant and compressive strength for five types of ordinary concrete have been undertaken, after 28 days of curing. As the main contribution in this work, the correlation model between the compressive strength and dielectric constant of GB concrete is realized

Table_3_Clinical characteristics and gene mutation profiles of chronic obstructive pulmonary disease in non-small cell lung cancer.docx

PurposeThe coexistence of chronic obstructive pulmonary disease (COPD) often leads to a worse prognosis in patients with non-small cell lung cancer (NSCLC). Meanwhile, approaches targeting specific genetic alterations have been shown to significantly improve the diagnosis and treatment outcomes of patients with NSCLC. Herein, we sought to evaluate the impact of COPD on the clinical manifestations and gene mutation profiles of NSCLC patients with both circulating tumor (ctDNA) and tumor DNA (tDNA).Materials and methodsThe influence of COPD on clinical features was observed in 285 NSCLC cohorts suffering from NSCLC alone, NSCLC coexisting with COPD, or NSCLC coexisting with prodromal changes in COPD (with emphysema, bullae, or chronic bronchitis). The gene mutation profiles of specific 168 NSCLC-related genes were further analyzed in the NSCLC sub-cohorts with formalin-fixed and paraffin-embedded tumor DNA (FFPE tDNA) samples and plasma circulating tumor DNA (PLA ctDNA) samples. Moreover, mutation concordance was assessed in tDNA and paired ctDNA of 110 NSCLC patients.ResultsRelative to patients with NSCLC alone, patients with NSCLC coexisting with COPD and prodromal changes presented with worse lung functions, more clinical symptoms, signs and comorbidities, and inconsistent gene mutation profiles. In addition, patients in the latter two groups exhibited a higher average frequency of gene mutation. Lastly, mutation concordance between tDNA and ctDNA samples was significantly reduced in NSCLC patients coexisting with COPD.ConclusionsCollectively, our findings revealed that coexistence of COPD leads to worse clinical manifestations and altered gene mutation profiles in patients with NSCLC. Additionally, for NSCLC patients with COPD, the use of ctDNA instead of tDNA may not be the most efficient approach to identifying gene mutations.</p

Table_2_Clinical characteristics and gene mutation profiles of chronic obstructive pulmonary disease in non-small cell lung cancer.doc

PurposeThe coexistence of chronic obstructive pulmonary disease (COPD) often leads to a worse prognosis in patients with non-small cell lung cancer (NSCLC). Meanwhile, approaches targeting specific genetic alterations have been shown to significantly improve the diagnosis and treatment outcomes of patients with NSCLC. Herein, we sought to evaluate the impact of COPD on the clinical manifestations and gene mutation profiles of NSCLC patients with both circulating tumor (ctDNA) and tumor DNA (tDNA).Materials and methodsThe influence of COPD on clinical features was observed in 285 NSCLC cohorts suffering from NSCLC alone, NSCLC coexisting with COPD, or NSCLC coexisting with prodromal changes in COPD (with emphysema, bullae, or chronic bronchitis). The gene mutation profiles of specific 168 NSCLC-related genes were further analyzed in the NSCLC sub-cohorts with formalin-fixed and paraffin-embedded tumor DNA (FFPE tDNA) samples and plasma circulating tumor DNA (PLA ctDNA) samples. Moreover, mutation concordance was assessed in tDNA and paired ctDNA of 110 NSCLC patients.ResultsRelative to patients with NSCLC alone, patients with NSCLC coexisting with COPD and prodromal changes presented with worse lung functions, more clinical symptoms, signs and comorbidities, and inconsistent gene mutation profiles. In addition, patients in the latter two groups exhibited a higher average frequency of gene mutation. Lastly, mutation concordance between tDNA and ctDNA samples was significantly reduced in NSCLC patients coexisting with COPD.ConclusionsCollectively, our findings revealed that coexistence of COPD leads to worse clinical manifestations and altered gene mutation profiles in patients with NSCLC. Additionally, for NSCLC patients with COPD, the use of ctDNA instead of tDNA may not be the most efficient approach to identifying gene mutations.</p

Image_2_Clinical characteristics and gene mutation profiles of chronic obstructive pulmonary disease in non-small cell lung cancer.tif

PurposeThe coexistence of chronic obstructive pulmonary disease (COPD) often leads to a worse prognosis in patients with non-small cell lung cancer (NSCLC). Meanwhile, approaches targeting specific genetic alterations have been shown to significantly improve the diagnosis and treatment outcomes of patients with NSCLC. Herein, we sought to evaluate the impact of COPD on the clinical manifestations and gene mutation profiles of NSCLC patients with both circulating tumor (ctDNA) and tumor DNA (tDNA).Materials and methodsThe influence of COPD on clinical features was observed in 285 NSCLC cohorts suffering from NSCLC alone, NSCLC coexisting with COPD, or NSCLC coexisting with prodromal changes in COPD (with emphysema, bullae, or chronic bronchitis). The gene mutation profiles of specific 168 NSCLC-related genes were further analyzed in the NSCLC sub-cohorts with formalin-fixed and paraffin-embedded tumor DNA (FFPE tDNA) samples and plasma circulating tumor DNA (PLA ctDNA) samples. Moreover, mutation concordance was assessed in tDNA and paired ctDNA of 110 NSCLC patients.ResultsRelative to patients with NSCLC alone, patients with NSCLC coexisting with COPD and prodromal changes presented with worse lung functions, more clinical symptoms, signs and comorbidities, and inconsistent gene mutation profiles. In addition, patients in the latter two groups exhibited a higher average frequency of gene mutation. Lastly, mutation concordance between tDNA and ctDNA samples was significantly reduced in NSCLC patients coexisting with COPD.ConclusionsCollectively, our findings revealed that coexistence of COPD leads to worse clinical manifestations and altered gene mutation profiles in patients with NSCLC. Additionally, for NSCLC patients with COPD, the use of ctDNA instead of tDNA may not be the most efficient approach to identifying gene mutations.</p

Table_6_Clinical characteristics and gene mutation profiles of chronic obstructive pulmonary disease in non-small cell lung cancer.docx

PurposeThe coexistence of chronic obstructive pulmonary disease (COPD) often leads to a worse prognosis in patients with non-small cell lung cancer (NSCLC). Meanwhile, approaches targeting specific genetic alterations have been shown to significantly improve the diagnosis and treatment outcomes of patients with NSCLC. Herein, we sought to evaluate the impact of COPD on the clinical manifestations and gene mutation profiles of NSCLC patients with both circulating tumor (ctDNA) and tumor DNA (tDNA).Materials and methodsThe influence of COPD on clinical features was observed in 285 NSCLC cohorts suffering from NSCLC alone, NSCLC coexisting with COPD, or NSCLC coexisting with prodromal changes in COPD (with emphysema, bullae, or chronic bronchitis). The gene mutation profiles of specific 168 NSCLC-related genes were further analyzed in the NSCLC sub-cohorts with formalin-fixed and paraffin-embedded tumor DNA (FFPE tDNA) samples and plasma circulating tumor DNA (PLA ctDNA) samples. Moreover, mutation concordance was assessed in tDNA and paired ctDNA of 110 NSCLC patients.ResultsRelative to patients with NSCLC alone, patients with NSCLC coexisting with COPD and prodromal changes presented with worse lung functions, more clinical symptoms, signs and comorbidities, and inconsistent gene mutation profiles. In addition, patients in the latter two groups exhibited a higher average frequency of gene mutation. Lastly, mutation concordance between tDNA and ctDNA samples was significantly reduced in NSCLC patients coexisting with COPD.ConclusionsCollectively, our findings revealed that coexistence of COPD leads to worse clinical manifestations and altered gene mutation profiles in patients with NSCLC. Additionally, for NSCLC patients with COPD, the use of ctDNA instead of tDNA may not be the most efficient approach to identifying gene mutations.</p