2,086 research outputs found
A General Analysis of Wtb anomalous Couplings
We investigate new physics effects on the Wtb effective couplings in a
model-independent manner. The new physics effects are summarized as four
independent couplings , , and . Using
single-top-quark productions and W-helicity fraction measurements at the LHC
and Tevatron, we perform a global fit to impose constraints on top quark
effective couplings. We introduce a set of parameters , , and
to study the correlations among Wtb effective couplings. We show that (i)
improving the measurements of and is important in
constraining the correlation of and ; (ii)
and are anti-correlated, which is sensitive to all the
experiments; (iii) and are also anti-correlated, which is
sensitive to the W-helicity measurements; (iv) the correlation between
and is sensitive to the precision of , and
measurements. The effective Wtb couplings are studied in three kinds of
new physics models: models, vector-like
quark models and Littlest Higgs model with and without T-parity. The Wtb
couplings in the left-right model and the un-unified model are sensitive to the
ratio of gauge couplings when the new heavy gauge boson's mass () is
less than several hundred GeV, but the constraint is loose if TeV.
The Wtb couplings in vector-like quark models and the Littlest Higgs models are
sensitive to the mixing angles of new heavy particles and SM particles. We also
include the constraints of the oblique T-parameter and Zbb couplings which
impose much tighter constraints on the mixing angles. We show that the Wtb
coupling constraints become relevant if the precision of single top production
cross section measurements could be reduced to 1\% relative to the SM
predictions in future.Comment: Chin. Phys. C in pres
The Top Quark Production Asymmetries and
A large forward-backward asymmetry is seen in both the top quark rapidity
distribution and in the rapidity distribution of charged leptons
from top quarks produced at the Tevatron. We study the kinematic
and dynamic aspects of the relationship of the two observables arising from the
spin correlation between the charged lepton and the top quark with different
polarization states. We emphasize the value of both measurements, and we
conclude that a new physics model which produces more right-handed than
left-handed top quarks is favored by the present data.Comment: accepted for publication in Physical Review Letter
Interpretations and Implications of the Top Quark Rapidity Asymmetries and
Forward-backward asymmetries and are observed in the
top quark rapidity distribution and in the rapidity distribution of charged
leptons from top quark decay at the Tevatron proton-antiproton collider,
and a charge asymmetry is seen in proton-proton collisions at the Large
Hadron Collider (LHC). In this paper, we update our previous studies of the
Tevatron asymmetries using the most recent data. We provide expectations for
at the LHC based first on model independent extrapolations from the
Tevatron, and second based on new physics models that can explain the Tevatron
asymmetries. We examine the relationship of the two asymmetries and
. We show their connection through the spin correlation
between the charged lepton and the top quark with different polarization
states. We show that the ratio of the two asymmetries provides independent
insight into new physics models that are invoked to fit the top quark
asymmetry. We emphasize the value of the measurement of both asymmetries, and
we conclude that a model which produces more right-handed than left-handed top
quarks is favored by the present Tevatron data.Comment: Some figures changed. A typo in appendix fixed. Published in Physical
Review
Top Quark Polarization As A Probe of Models with Extra Gauge Bosons
New heavy gauge bosons exist in many models of new physics beyond the
standard model of particle physics. Discovery of these W^\prime and Z^\prime
resonances and the establishment of their spins, couplings, and other quantum
numbers would shed light on the gauge structure of the new physics. The
measurement of the polarization of the SM fermions from the gauge boson decays
would decipher the handedness of the coupling of the new states, an important
relic of the primordial new physics symmetry. Since the top quark decays
promptly, its decay preserves spin information. We show how decays of new gauge
bosons into third generation fermions (W^\prime \to tb, Z^\prime\to t\bar{t})
can be used to determine the handedness of the couplings of the new states and
to discriminate among various new physics models
Top Quark Forward-Backward Asymmetry and Same-Sign Top Quark Pairs
The top quark forward-backward asymmetry measured at the Tevatron collider
shows a large deviation from standard model expectations. Among possible
interpretations, a non-universal model is of particular interest as
it naturally predicts a top quark in the forward region of large rapidity. To
reproduce the size of the asymmetry, the couplings of the to
standard model quarks must be large, inevitably leading to copious production
of same-sign top quark pairs at the energies of the Large Hadron Collider
(LHC). We explore the discovery potential for and production in
early LHC experiments at 7-8 TeV and conclude that if {\it no} signal is
observed with 1 fb of integrated luminosity, then a non-universal
alone cannot explain the Tevatron forward-backward asymmetry.Comment: Tevatron limit from same-sign tt search adde
Chloroquinone Inhibits Cell Proliferation and Induces Apoptosis in Nasopharyngeal Carcinoma Cell Lines
Purpose: To demonstrate the role of chloroquinone (CQ) in inducing apoptosis in HONE-1 and HNE-1, nasopharyngeal carcinoma (NPC) cell lines.Methods: Water-soluble tetrazolium salt (WST)-1 assay was used for the determination of cell proliferation while an inverted microscope was employed for the analysis of alterations in the morphology of the cells.Results: CQ treatment led to a significant reduction in the rate of cell proliferation in NPC cells after 48 h. In HONE-1 and HNE-1 cell lines viability was reduced to 89 and 82 %, respectively on treatment with 10 μΜ concentration of CQ without affecting normal human skin keratinocyte cell line, K38. The expression of Ki67, a marker for proliferation as well as proliferating cell nuclear antigen (PCNA), decreased in the CQ-treated NPC cells. Morphological examination of NPC cells revealed cell apoptosis on treatment with CQ after 48 h. Treatment of NPC cells with CQ induced activation of caspases and DNA was damaged which further confirmed CQ mediated induction of apoptosis. The level of apoptotic cells in CQ treated and untreated control HONE-1 cell cultures was 53.67 and 3.78 %, respectively (p < 0.05). In addition, CQ treatment decreased reactive oxygen species (ROS) generation in NPC cells.Conclusion: CQ inhibits cell proliferation of NPC cells by inducing apoptosis via DNA damage, and may be of therapeutic use for the treatment of NPC. However, this requires clinical investigation to ascertain its therapeutic potential.Keywords: Chloroquinone, Caspases, Apoptosis, Nuclear antigen, Nasopharyngeal carcinom
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