A Causal And-Or Graph Model for Visibility Fluent Reasoning in Tracking Interacting Objects

Tracking humans that are interacting with the other subjects or environment remains unsolved in visual tracking, because the visibility of the human of interests in videos is unknown and might vary over time. In particular, it is still difficult for state-of-the-art human trackers to recover complete human trajectories in crowded scenes with frequent human interactions. In this work, we consider the visibility status of a subject as a fluent variable, whose change is mostly attributed to the subject's interaction with the surrounding, e.g., crossing behind another object, entering a building, or getting into a vehicle, etc. We introduce a Causal And-Or Graph (C-AOG) to represent the causal-effect relations between an object's visibility fluent and its activities, and develop a probabilistic graph model to jointly reason the visibility fluent change (e.g., from visible to invisible) and track humans in videos. We formulate this joint task as an iterative search of a feasible causal graph structure that enables fast search algorithm, e.g., dynamic programming method. We apply the proposed method on challenging video sequences to evaluate its capabilities of estimating visibility fluent changes of subjects and tracking subjects of interests over time. Results with comparisons demonstrate that our method outperforms the alternative trackers and can recover complete trajectories of humans in complicated scenarios with frequent human interactions.Comment: accepted by CVPR 201

Point Cloud Registration for LiDAR and Photogrammetric Data: a Critical Synthesis and Performance Analysis on Classic and Deep Learning Algorithms

Recent advances in computer vision and deep learning have shown promising performance in estimating rigid/similarity transformation between unregistered point clouds of complex objects and scenes. However, their performances are mostly evaluated using a limited number of datasets from a single sensor (e.g. Kinect or RealSense cameras), lacking a comprehensive overview of their applicability in photogrammetric 3D mapping scenarios. In this work, we provide a comprehensive review of the state-of-the-art (SOTA) point cloud registration methods, where we analyze and evaluate these methods using a diverse set of point cloud data from indoor to satellite sources. The quantitative analysis allows for exploring the strengths, applicability, challenges, and future trends of these methods. In contrast to existing analysis works that introduce point cloud registration as a holistic process, our experimental analysis is based on its inherent two-step process to better comprehend these approaches including feature/keypoint-based initial coarse registration and dense fine registration through cloud-to-cloud (C2C) optimization. More than ten methods, including classic hand-crafted, deep-learning-based feature correspondence, and robust C2C methods were tested. We observed that the success rate of most of the algorithms are fewer than 40% over the datasets we tested and there are still are large margin of improvement upon existing algorithms concerning 3D sparse corresopondence search, and the ability to register point clouds with complex geometry and occlusions. With the evaluated statistics on three datasets, we conclude the best-performing methods for each step and provide our recommendations, and outlook future efforts.Comment: 7 figure

Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system.

Precise genetic modifications in model animals are essential for biomedical research. Here, we report a programmable "base editing" system to induce precise base conversion with high efficiency in zebrafish. Using cytidine deaminase fused to Cas9 nickase, up to 28% of site-specific single-base mutations are achieved in multiple gene loci. In addition, an engineered Cas9-VQR variant with 5'-NGA PAM specificities is used to induce base conversion in zebrafish. This shows that Cas9 variants can be used to expand the utility of this technology. Collectively, the targeted base editing system represents a strategy for precise and effective genome editing in zebrafish.The use of base editing enables precise genetic modifications in model animals. Here the authors show high efficient single-base editing in zebrafish using modified Cas9 and its VQR variant with an altered PAM specificity

The association between periodontal disease and the risk of myocardial infarction: a pooled analysis of observational studies

Quality scores of case–control and cohort studies using Newcastle-Ottawa Scale. (PDF 37 kb