From collection resources to intelligent data: Construction of intelligent digital humanities platform for local historical documents of Shanghai Jiao Tong University

Local historical documents originated from daily life of people belong to special collection resources that were not published publicly. They are valuable assets of universities and libraries. At present, most documents had only finished digitalization or partial datalization work. However, the requirements of deep knowledge mining in documents data, providing visual analysis, and effectively supporting the research of historic humanities scholars had not been fully met. Taking the local historical documents project of Shanghai Jiao Tong University as an example, using relevant techniques of digital humanities (DH), the in-depth analysis and utilization research of documents data were carried out. On the one hand, the core database of the documents was established based on standardizing metadata cataloguing and establishing metadata association. On the other hand, based on the core database, an intelligent DH system platform was constructed. The platform is to realize full-field retrieval and display of the documents, text analysis, association analysis, statistics, and visual presentation of knowledge. In addition, in the process of using the platform for research, humanities scholars can continuously expand the data dimensions and the relationships between data, achieve intelligent supplementation of documents data and platform self-learning. The concept of DH has led to a new direction of database construction and platform development. In the exploration and practice of DH, libraries should continue to widen thinking, improve service and innovation capabilities, and provide better research perspectives, research environments, research support, and research experience for humanities scholars.GECEM Project (ERC-Starting Grant), ref. 679371, Horizon 2020, project hosted at UPOCenter for Digital Sources of Chinese History, Library at Shanghai Jiao Tong Universit

Combined 624-nm and 850-nm illumination at low rates leads to enhanced inhibition of Candida albicans

Background: To determine whether combinations of red and infrared light could improve inhibition of Candida albicans and whether combining wavelengths and altering rate of energy delivery could prevent the formation of resistance to light energy.Methods: C. albicans was tested because of the common appearance in human skin and mucous membrane infections. The organism was treated in vitro with a combination of 624-nm (red) and 850-nm (infrared) light emitted from a supraluminous diode (SLD) array. Doses of 9, and 30 J/cm2 were used. Rate of energy delivery was also manipulated. Colony counts were performed and compared to untreated controls using Student t tests and one-way ANOVA with Tukey post hoc analysis.Results: The combination of 624 and 850-nm light energy at 30 J/cm2 was an effective (p ≤ 0.05) inhibitor of C. albicans across all seven stages of the experiment. The combination of 624 and 850-nm wavelengths produced a maximum kill rate [{control – treated / control} X 100] of 76.24% and an average kill rate of 54% across the seven stages of the experiment.Conclusions: A Combination of 624-nm and 850-nm light from an SLD array can inhibit the growth of C. albicans in vitro. Altering delivery rate of the energy can delay resistance formation in this organism.

Effects of temperature,illumination and cell density on growth and competition of three species of water-bloom cyanobacteria

The effects of temperature,illumination and initial algae cell density on growth and competition of Microcystis aeruginosa,Merismopedia minima and Pseudanabaenamucicola were studied by the method of single factor experiment and orthogonal experiment.The results showed that both M.aeruginosa and M.minimacould grow optimally under higher temperature and/or higher illumination.P.mucicola has competitive advantage only under lower temperature and lower illumination.Under the same temperature and illumination conditions,the initial density of algae cells is the key factor for competing the dominant species position.In addition to controlling the input of nutrients and other pollutants,paying attention to the changes of phytoplankton community structure,controlling and reducing the biomass of cyanobacteria before the water blooms may be another effective way to control cyanobacterial blooms in freshwater lakes or reservoirs

Inhibition of Mycobacterium smegmatis using near-IR and blue light

Background: Objective of current study is to determine whether near-IR, alone or combined with blue light and delivered at a low rate, could lower the dose needed to effectively inhibit Mycobacterium smegmatis in vitro. We have studied the effect of blue light on M. smegmatis and found that a bactericidal outcome can be obtained with high doses of blue light.Methods: The organism was treated in vitro with 464, 850 and combined 464 & 850nm light emitted from a supraluminous diode (SLD) array. Doses of 30, 45 and 60 J/cm2 were used. Colony counts were performed and compared to untreated controls using Student t tests, a two-way Repeated Measures ANOVA and a one-way ANOVA with Tukey post hoc analysis.Results: Statistically significant inhibition was observed for each individual wavelength and dose combination (p < 0.05). Two-way ANOVA demonstrated an interaction effect between wavelength and dose (F1, 9 = 358.585; p - 0.000). Post hoc analysis using one-way ANOVA (F2, 27 = 11.211; p = 0.00) and Tukey’s HSD identified 850nm at 45 J/cm2 to be the most effective wavelength / dose combination. Conclusions: 850nm irradiation delivered at 45 J/cm2 is a wavelength /dose combination that can be expected to produce a significant inhibition of M. smegmatis in vitro.