Reduction of UNil for finite groups with normal abelian Sylow 2-subgroup

Let F be a finite group with a Sylow 2-subgroup S that is normal and abelian. Using hyperelementary induction and cartesian squares, we prove that Cappell's unitary nilpotent groups UNil_*(Z[F];Z[F],Z[F]) have an induced isomorphism to the quotient of UNil_*(Z[S];Z[S],Z[S]) by the action of the group F/S. In particular, any finite group F of odd order has the same UNil-groups as the trivial group. The broader scope is the study of the L-theory of virtually cyclic groups, based on the Farrell--Jones isomorphism conjecture. We obtain partial information on these UNil when S is a finite abelian 2-group and when S is a special 2-group.Comment: 29 pages, revision of decorations, correction of Homological Reductio

Endeavor agility on consumption value through affirming an acceptable degree of utilization esteem for new items

Purpose: This comparative study holistically assesses the agility that turns into the standard of business and methods for progress. Design/Methodology/Approach: The contribution and the relevant methodology based on a duality of purposes. They are (i) quantitative research system that utilized to complete the investigation and (ii) both fundamental and auxiliary sources used to assemble information. Findings: Based on the holistically implied arguments and yielded results, it proposed that the writing audit results various parameters to clarify nimbleness and utilization esteems, which utilized to build a survey. At that point, the examination led to design a fitting example between use esteems and hidden agility measurements. Practical implications: Addressing to dual purposes, this study sheds new light on the Mallintercept method block strategy that utilized to gather reactions. Originality/Value: Although this study organically builds upon recent studies, this area gives a detail examination of the investigation. The survey has a field containing the segment profile of the respondents. This examination applies the utilization esteem model as the essential system, which incorporated the practical worth, the social worth, the passionate worth, the epistemic worth, and the restrictive worth.peer-reviewe

Role of miR-155 and miR-146a in Mast Cell Function

Mast cells are resident immune cells abundantly found in the tissue at the host-environment interface, where they play a critical role in inflammatory allergic responses. Mast cell responses may be regulated by the cytokine milieu at the site of inflammation. Recent studies have revealed microRNAs to be important in altering cytokine signaling in immune cells. Here, we demonstrate for the first time that IL-10 and IL-33 induce miR-155 and miR-146a, respectively, to alter mast cell functions. We report that IL-10 enhanced IgE induced activation of mast cells. IL-10 effects are dependent on Stat3 activation, which elicits miR-155 expression, resulting in a loss of suppressor of cytokine signaling-1 (SOCS-1). The importance of miR-155 was demonstrated by the inability of IL-10 to enhance anaphylaxis in miR-155–deficient mice. Additionally, we show that IL-33 treatment greatly enhances miR-146a expression in mast cells and in mast cell derived exosomes. miR-146a induction is dependent on MyD88 and NFκB and seems to negatively regulate ST2 signaling, which is demonstrated by the hyperresponsiveness of miR-146a knockout BMMC in response to IL-33. Our preliminary data suggest that miR-146a serves as a feedback negative regulator of IL-33 signaling by targeting IRAK proteins. miR-155 and miR-146a are key microRNAs that regulate a range of immune functions. Taken together, our results reveal two novel microRNA pathways that regulate mast cell IgE and IL-33 induced responses

Peace Conceptual Metaphor Analysis in the Afghanistan Peacemaking Process - Case Study: Afghanistan Peace Map

In this research, we have used the descriptive-analytic method. The main purpose of this paper is to show the reflection and perception of the peace conceptual metaphor in Afghanistan's discourse space on the basis of "conceptual metaphor theory." Humans typically reflect on concrete or more physical things, according to this linguistic theory. The findings of this study show that the country's peace-making operatives reflected the abstract and nonphysical concept of peace on a variety of concrete and physical things. For example, on the basis of the "Afghanistan Peace Map" context, the peace abstract concept is reflected on the experimental and objective concepts, like: "journey", "structure", and "live objects." Therefore, the conceptual metaphors of "peace is journey", "peace is structure" and "peace is live objects" are the three more prevalent concepts that are reflected in this context. These metaphors are not only more prevalent and user-friendly in the context of the "Afghanistan peace map," but research into published contexts in the Afghanistan peace-making process reveals that these metaphors flowed in the substructure of all peace contexts