1,180 research outputs found

    Study on conjugate heat transfer in a photovoltaic wall

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    2002-2003 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    Numerical Analysis of a Dual Polarization Mode-Locked Laser with a Quarter Wave Plate

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    Dynamical behaviors and frequency characteristics of an active mode-locked laser with a quarter wave plate (QWP) are numerically studied by using a set pf vectorial laser equation. Like a polarization self-modulated laser, a frequency shift of half the cavity mode spacing exists between the eigen-modes in the two neutral axes of QWP. Within the active medium, the symmetric gain and cavity structure maintain the pulse's circular polarization with left-hand and right-hand in turn for each round trip. Once the left-hand or right-hand circularly polarized pulse passes through QWP, its polarization is linear and the polarized direction is in one of the directions of i45o with respect to the neutral axes of QWP. The output components in the directions of i45" from the mirror close to QWP are all linearly polarized with a period of twice the round-trip time

    Temperature-based stiffness identification of que-Ti’s in a historic Tibetan timber building

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    © 2017 Taylor & Francis Group, London. Que-Ti, like the corbel brackets connecting beam and column in modern structures, is an important component in typical Tibetan historic timber buildings. It transfers shear, compression and bending moment by slippage and deformation of components as well as limited joint rotation. A rigorous analytical model of Que-Ti is needed for predicting the behaviour of a timber structure under load. However, few researches have been done with this model, particularly on the parameters describing the performances of this joint under load. The equivalent stiffness of a Que-Ti connection in its operating state is determined by using ambient temperature variations as a forcing function in the complete input(temperature)-output(local mechanical strains) relationship when it is incorporated in a finite element model of the structure. The identification is done iteratively via correlating the calculated strain responses with measured data

    3-D Ultrastructure of O. tauri: Electron Cryotomography of an Entire Eukaryotic Cell

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    The hallmark of eukaryotic cells is their segregation of key biological functions into discrete, membrane-bound organelles. Creating accurate models of their ultrastructural complexity has been difficult in part because of the limited resolution of light microscopy and the artifact-prone nature of conventional electron microscopy. Here we explored the potential of the emerging technology electron cryotomography to produce three-dimensional images of an entire eukaryotic cell in a near-native state. Ostreococcus tauri was chosen as the specimen because as a unicellular picoplankton with just one copy of each organelle, it is the smallest known eukaryote and was therefore likely to yield the highest resolution images. Whole cells were imaged at various stages of the cell cycle, yielding 3-D reconstructions of complete chloroplasts, mitochondria, endoplasmic reticula, Golgi bodies, peroxisomes, microtubules, and putative ribosome distributions in-situ. Surprisingly, the nucleus was seen to open long before mitosis, and while one microtubule (or two in some predivisional cells) was consistently present, no mitotic spindle was ever observed, prompting speculation that a single microtubule might be sufficient to segregate multiple chromosomes

    A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome

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    Down syndrome, caused by an extra copy of chromosome 21, is associated with a greatly increased risk of early onset Alzheimer disease. It is thought that this risk is conferred by the presence of three copies of the gene encoding amyloid precursor protein (APP), an Alzheimer risk factor, although the possession of extra copies of other chromosome 21 genes may also play a role. Further study of the mechanisms underlying the development of Alzheimer disease in Down syndrome could provide insights into the mechanisms that cause dementia in the general population

    Multi-Constellation Signal Design Aided Affine Frequency Division Multiplexing for 6G Communication Systems

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    As one of the novel waveforms recently proposed for future 6G communications, affine frequency division multiplexing (AFDM) is capable of combating the effects of the high Doppler and achieving full diversity over high mobility wireless channels. In this paper, hybrid multi-constellations for AFDM systems are proposed. A hybrid multi-constellation is obtained by eliminating points with the largest energy and by geometric interpolation among the signal points of the traditional single constellation. Two types of hybrid multi-constellation schemes, namely multiconstellation aided AFDM-Type 1 (MC-AFDM-T1) and multiconstellation aided AFDM-Type 2 (MC-AFDM-T2), are designed to improve AFDM system reliability. Monte Carlo simulations demonstrate that the proposed MC-AFDM-T1 and MC-AFDMT2 schemes are capable of achieving better symbol error rate (SER) compared to that of the original-AFDM (Ori-AFDM)

    Two Birds with One Stone? Possible Dual-Targeting H1N1 Inhibitors from Traditional Chinese Medicine

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    The H1N1 influenza pandemic of 2009 has claimed over 18,000 lives. During this pandemic, development of drug resistance further complicated efforts to control and treat the widespread illness. This research utilizes traditional Chinese medicine Database@Taiwan (TCM Database@Taiwan) to screen for compounds that simultaneously target H1 and N1 to overcome current difficulties with virus mutations. The top three candidates were de novo derivatives of xylopine and rosmaricine. Bioactivity of the de novo derivatives against N1 were validated by multiple machine learning prediction models. Ability of the de novo compounds to maintain CoMFA/CoMSIA contour and form key interactions implied bioactivity within H1 as well. Addition of a pyridinium fragment was critical to form stable interactions in H1 and N1 as supported by molecular dynamics (MD) simulation. Results from MD, hydrophobic interactions, and torsion angles are consistent and support the findings of docking. Multiple anchors and lack of binding to residues prone to mutation suggest that the TCM de novo derivatives may be resistant to drug resistance and are advantageous over conventional H1N1 treatments such as oseltamivir. These results suggest that the TCM de novo derivatives may be suitable candidates of dual-targeting drugs for influenza.National Science Council of Taiwan (NSC 99-2221-E-039-013-)Committee on Chinese Medicine and Pharmacy (CCMP100-RD-030)China Medical University and Asia University (CMU98-TCM)China Medical University and Asia University (CMU99-TCM)China Medical University and Asia University (CMU99-S-02)China Medical University and Asia University (CMU99-ASIA-25)China Medical University and Asia University (CMU99-ASIA-26)China Medical University and Asia University (CMU99-ASIA-27)China Medical University and Asia University (CMU99-ASIA-28)Taiwan Department of Health. Clinical Trial and Research Center of Excellence (DOH100-TD-B-111-004)Taiwan Department of Health. Cancer Research Center of Excellence (DOH100-TD-C-111-005

    An Adaptive MDS-coded OFDM Waveform for Low-Altitude ISAC: Design and Optimization

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    The low-altitude economy (LAE), an emerging economic paradigm encompassing various flight activities in low-altitude airspace, has attracted widespread attention from academia and industry due to its appealing economic and social benefits. In this paper, we investigate the design of integrated sensing and communication (ISAC) waveforms for LAE applications. Specifically, we propose an adaptive ISAC waveform, which integrates the maximum distance separable (MDS) code and index modulation (IM) into the orthogonal frequency division multiplexing (OFDM) waveform, namely A-MDS-OFDM-IM. This design combines the hybrid benefits of MDS code, IM, and OFDM techniques, i.e., the error detection capability of MDS code, the high spectral efficiency (SE) of IM, and the high sensing resolution of OFDM, thereby enabling robust communication and sensing. A comprehensive performance analysis of A-MDSOFDM- IM is provided, including its bit error rate (BER), peak-to- sidelobe level (PSL), and peak-to-average power ratio (PAPR). Moreover, to address the high PAPR issue of A-MDS-OFDMIM, we develop an adaptive design criterion based on the alternating direction method of multipliers (ADMM), which is capable of jointly optimizing the communication, sensing, and PAPR performance of the proposed system. Simulation results demonstrate that the proposed waveform achieves better BER performance than conventional OFDM-based waveforms under a non-ideal high power amplifier (HPA), owing to its low-PAPR characteristic. Additionally, the proposed waveform ensures robust sensing with satisfactory PSL performance, making it a promising ISAC waveform for LAE applications

    Choroidal thickness in school children: The Gobi Desert Children Eye Study

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    Train model acceleration and deceleration

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    In order to accelerate a heavy train model with great dimensions to a speed higher than 300 km h(-1) in a moving train model testing system, compressed air is utilized to drive the train model indirectly. The gas from an air gun pushes the piston in an accelerating tube forward. The piston is connected to the trailer through a rope, and the trailer pulls the train model to the desired speed. After the testing section, the train model enters the deceleration section. The speed of the train model gradually decreases because of the braking force of the magnetic braking device on the bottom of the train model and the steel plates fixed on the floor of this device. The dissipation of kinetic energy of the trailer is also based on a similar principle. The feasibility of these methods has been examined in a 180 m-long moving train model testing system. The speed of the trailer alone reaches up to 490 km h(-1). Consequently, a 34.8 kg model accelerates up to 350 km h(-1); the smooth and safe stopping of the model is also possible
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