Genome Sequence and Transcriptome Analysis of the Radioresistant Bacterium Deinococcus gobiensis: Insights into the Extreme Environmental Adaptations

The desert is an excellent model for studying evolution under extreme environments. We present here the complete genome and ultraviolet (UV) radiation-induced transcriptome of Deinococcus gobiensis I-0, which was isolated from the cold Gobi desert and shows higher tolerance to gamma radiation and UV light than all other known microorganisms. Nearly half of the genes in the genome encode proteins of unknown function, suggesting that the extreme resistance phenotype may be attributed to unknown genes and pathways. D. gobiensis also contains a surprisingly large number of horizontally acquired genes and predicted mobile elements of different classes, which is indicative of adaptation to extreme environments through genomic plasticity. High-resolution RNA-Seq transcriptome analyses indicated that 30 regulatory proteins, including several well-known regulators and uncharacterized protein kinases, and 13 noncoding RNAs were induced immediately after UV irradiation. Particularly interesting is the UV irradiation induction of the phrB and recB genes involved in photoreactivation and recombinational repair, respectively. These proteins likely include key players in the immediate global transcriptional response to UV irradiation. Our results help to explain the exceptional ability of D. gobiensis to withstand environmental extremes of the Gobi desert, and highlight the metabolic features of this organism that have biotechnological potential

Highly luminescent hydrogels synthesized by covalent grafting of lanthanide complexes onto PNIPAM via one-pot free radical polymerization

202308 bcvcAccepted ManuscriptOthersThe National Natural Science Foundation of China; Excellent Youth Foundation of He’nan Scientific Committee; Program for Innovative Research Team (in Science and Technology) in University of Henan Province; Innovation Scientists and Technicians Troop Construction Projects of Henan Province; Henan Province Key Discipline of Applied ChemistryPublishe

Water-soluble luminescent hybrid aminoclay grafted with lanthanide complexes synthesized by a michael-like addition reaction and its gas sensing application in PVP nanofiber

202308 bcvcAccepted ManuscriptOthersThe National Natural Science Foundation of China; The Innovation Scientists and Technicians Troop Construction Projects of Henan Province; The Program for Innovative Research Team in University of Henan Province; Key scientific and technological project of Henan Province; High Level Personnel Fund of Zhoukou Normal UniversityPublishe

Controllable synthesis of lanthanide Yb3+ and Er3+ co-doped AWO(4) (A = Ca, Sr, Ba) micro-structured materials: phase, morphology and up-conversion luminescence enhancement

201809 bcrcAccepted ManuscriptRGCOthersThe National Natural Science Foundation of China; The Innovation Scientists and Technicians Troop Construction Projects of Henan ProvincePublishe

Incidence of diarrhea caused by rotavirus infections in rural Zhengding, China: prospective, population-based surveillance.

Rotavirus is the pathogen most commonly associated with severe gastroenteritis in young children in the People's Republic of China, yet there are few population-based data on the incidence of rotavirus infection. The present study investigated the burden of rotavirus diarrhea and rotavirus infections in rural China, according to age. Population-based surveillance was used to study the incidence of rotavirus infection among children <5 years of age in 4 townships of Zhengding County, Hebei Province, China. The total population in the catchment area in 2002 was 75,630 individuals, including 2997 children aged <5 years. Stool samples were obtained and were tested for rotavirus antigen by use of an enzyme-linked immunosorbent assay. During 2002, a total of 2010 cases of diarrhea were detected among children <5 years of age. The incidence of treated cases of diarrhea was 671 cases/1000 children/year for children <5 years of age, and it was highest for children <12 months of age (1467 cases/1000 children/year). The estimated incidence of rotavirus infection was 151 cases/1000 children/year for children <5 years of age. The highest incidence of rotavirus infection was among children aged 1-2 years (340 cases/1000 children/year). Widespread immunization of children against rotavirus before 6 months of age should be considered for the control of rotavirus diarrhea