Systematic Digitized Treatment of Engineering Line-Diagrams

YesIn engineering design, there are many functional relationships which are difficult to express into a simple and exact mathematical formula. Instead they are documented within a form of line graphs (or plot charts or curve diagrams) in engineering handbooks or text books. Because the information in such a form cannot be used directly in the modern computer aided design (CAD) process, it is necessary to find a way to numerically represent the information. In this paper, a data processing system for numerical representation of line graphs in mechanical design is developed, which incorporates the process cycle from the initial data acquisition to the final output of required information. As well as containing the capability for curve fitting through Cubic spline and Neural network techniques, the system also adapts a novel methodology for use in this application: Grey Models. Grey theory have been used in various applications, normally involved with time-series data, and have the characteristic of being able to handle sparse data sets and data forecasting. Two case studies were then utilized to investigate the feasibility of Grey models for curve fitting. Furthermore, comparisons with the other two established techniques show that the accuracy was better than the Cubic spline function method, but slightly less accurate than the Neural network method. These results are highly encouraging and future work to fully investigate the capability of Grey theory, as well as exploiting its sparse data handling capabilities is recommended

Graphene-based hybrid plasmonic waveguide for highly efficient broadband mid-infrared propagation and modulation

© 2018 Optical Society of America. In this paper, a graphene-based hybrid plasmonic waveguide is proposed for highly efficient broadband surface plasmon polariton (SPP) propagation and modulation at mid-infrared (mid-IR) spectrum. The hybrid plasmonic waveguide is composed of a monolayer graphene sheet in the center, a polysilicon gating layer, and two inner dielectric buffer layers and two outer parabolic-ridged silicon substrates symmetrically placed on both sides of the graphene. Owing to the unique parabolic-ridged waveguide structure, the light-graphene interaction and subwavelength SPPs confinement of the fundamental SPP mode for the hybrid waveguide can be significantly increased. Under the graphene chemical potential of 1.0 eV, the proposed waveguide can achieve outstanding SPP propagation performance with long propagation length of 12.1-16.7 μm and small normalized mode area of ~10−4 in the frequency range of 10-20 THz, exhibiting more than one order smaller in the normalized mode area while remaining the propagation length almost the same level with respect to the hybrid plasmonic waveguide without parabolic ridges. By tuning the graphene chemical potential from 0.1 to 1.0 eV, we demonstrate the waveguide has a modulation depth greater than 51% for the frequency ranging from 10 to 20 THz and reaches a maximum of nearly 100% at the frequency higher than 18 THz. Benefitting from the excellent broadband mid-IR propagation and modulation performance, the graphene-based hybrid plasmonic waveguide may open up a new way for various mid-IR waveguides, modulators, interconnects and optoelectronic devices

Expression and Significance of RANTES and MCP-1 in Renal Tissue With Chronic Renal Allograft Dysfunction

AbstractBackgroundTo investigate the expression of RANTES (regulated upon activation, normal T-cell–expressed and –secreted) and monocyte chemoattractant protein–1 (MCP-1) in renal allografts with chronic renal allograft dysfunction (CRAD), and explore its relationship with interstitial fibrosis and tubular atrophy (IF/TA).MethodsAn immunohistochemical assay and computer-assisted, genuine colored image analysis system were used to detect the expression of RANTES and MCP-1 in renal allografts with CRAD. The relationship among the expression level of MCP-1, RANTES, and the grade of inflammatory cell infiltration, interstitial fibrosis, and tubular atrophy in renal allografts were analyzed. Ten specimens of healthy renal tissue were used as controls.ResultsCompared to the normal tissues, the expressions of RANTES and MCP-1 were significantly higher in the renal tissues with CRAD (P < .001), and the expressions tended to increase along with the pathological grade of IF/TA. The expression of RANTES and MCP-1 were positively correlated with the pathological grades of IF/TA (r = 0.940 and 0.954 respectively, P < .001 for both).ConclusionIn renal allograft tissue with CRAD, the up-regulated expressions of RANTES and MCP-1 may be related to the progression of chronic renal allograft dysfunction and allograft fibrosis

Fast and robust chromatic dispersion estimation using auto-correlation of signal power waveform for DSP based- coherent systems

2011-2012 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

An improved calcium chloride method preparation and transformation of competent cells

Transformation is one of the fundamental and essential molecular cloning techniques. In this paper, we have reported a modified method for preparation and transformation of competent cells. This modifiedmethod, improved from a classical protocol, has made some modifications on the concentration of calcium chloride and competent bacteria solution, rotation speed in centrifugation and centrifugationtime. It was found that the optimal transformation efficiency were obtained when the concentration of CaCl2 was 75 mmol/l, OD600 of the culture meets 0.35 to 0.45, the temperature of rotation was 4°C , rotation speed was 1000 g and rotation time was 5 min. Even more, we also found out that the transformation efficiency would increase about 10 to 30 times when adding 15% glycerine into CaCl2 solution. The transformation efficiency, using our new method, reaches 108cf u/μg and higher than ultra-competent Escherichia coli method. This method will improve the efficiency in the molecular cloning and the construction of gene library.Keywords: Competent cells, CaCl2, improved method, transformation, glycerine, transformation efficienc

A five-gene signature as a potential predictor of metastasis and survival in colorectal cancer.

To understand the molecular mechanisms of metastasis and prognosis of colorectal cancer (CRC), we isolated single cell-derived progenies (SCPs) from SW480 cells in vitro and compared their metastatic potential in an orthotopic CRC tumour model in vivo. Two groups of SCPs with the capability of high and low metastasis, respectively, were obtained. By analysing the gene expression profiles of high (SCP51), low (SCP58) metastatic SCPs, and their parental cell line (SW480/EGFP), we demonstrated that 143 genes were differentially expressed either between SCP51 and SCP58 or between SCP58 and SW480/EGFP. Gene-annotation enrichment analysis of DAVID revealed 80 genes in the top ten clusters of the analysis (gene enrichment score > 1). Of the 80-gene set, 32 genes are potentially involved in metastasis, as revealed by Geneclip. Five putative metastatic genes (LYN, SDCBP, MAP4K4, DKK1, and MID1) were selected for further validations. Immunohistochemical analysis in a cohort of 181 CRC clinical samples showed that the individual expression of LYN, MAP4K4, and MID1, as well as the five-gene signature, was closely correlated with lymph node metastasis in CRC patients. More importantly, the individual expression of LYN, MAP4K4, SDCBP, and MID1, as well as the five-gene signature, was significantly correlated with overall survival in CRC patients. Thus, our five-gene signature may be able to predict metastasis and survival of CRC in the clinic, and opens new perspectives on the biology of CRC

BiOX (X = Cl, Br, I) photocatalysts prepared using NaBiO 3 as the Bi source: Characterization and catalytic performance

The Bismuth oxyhalides, crystalline BiOX (X = Cl, Br, I) were prepared via a facile method, using NaBiO 3 and HX aqueous solutions as the raw materials for the first time. The systematic microstructure and optical property characterizations of the BiOX photocatalysts demonstrated the reliability of this new and facile preparation approach. The photocatalytic activity on the degradation of typical phenolic endocrine disrupting chemicals over BiOX and P25 were evaluated under Xenon-light irradiation and the initial photocatalytic mechanism was discussed based on the band edge potential analysis. © 2009.postprin

The scheme for the database building and updating of 1∶10 000 digital elevation models

Author name used in this publication: LI Zhilin2000-2001 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Light-Front Quantization and AdS/QCD: An Overview

We give an overview of the light-front holographic approach to strongly coupled QCD, whereby a confining gauge theory, quantized on the light front, is mapped to a higher-dimensional anti de Sitter (AdS) space. The framework is guided by the AdS/CFT correspondence incorporating a gravitational background asymptotic to AdS space which encodes the salient properties of QCD, such as the ultraviolet conformal limit at the AdS boundary at $z \to 0$, as well as modifications of the geometry in the large $z$ infrared region to describe confinement and linear Regge behavior. There are two equivalent procedures for deriving the AdS/QCD equations of motion: one can start from the Hamiltonian equation of motion in physical space time by studying the off-shell dynamics of the bound state wavefunctions as a function of the invariant mass of the constituents. To a first semiclassical approximation, where quantum loops and quark masses are not included, this leads to a light-front Hamiltonian equation which describes the bound state dynamics of light hadrons in terms of an invariant impact variable $\zeta$ which measures the separation of the partons within the hadron at equal light-front time. Alternatively, one can start from the gravity side by studying the propagation of hadronic modes in a fixed effective gravitational background. Both approaches are equivalent in the semiclassical approximation. This allows us to identify the holographic variable $z$ in AdS space with the impact variable $\zeta$. Light-front holography thus allows a precise mapping of transition amplitudes from AdS to physical space-time. The internal structure of hadrons is explicitly introduced and the angular momentum of the constituents plays a key role.Comment: Invited talk presented by GdT at the XIV School of Particles and Fields, Morelia, Mexico, November 8-12, 201