Phylogenetic trees for each region of all available prototype EV B strains.

<p>Trees were rooted with PV1. Bootstrap values below 50 were removed. Bars indicate nucleotide substitution distance.</p

Phylogenetic trees for each genome fragment of all available prototype EV B strains.

<p>Trees were rooted with PV1. Bootstrap values below 50 were removed. Bars indicate nucleotide substitution distance.</p

Similarity plot comparing NZ2284 with all available prototype EV B strains and PV1.

<p>Schematic above the graph indicates the position of each gene within the EV genome.</p

BEAST xml file - B/Yamagata

Beast input file (xml) with data and parameters used for Bayesian phylogenetic analysis of the HA dataset of B/Yamagata viruses isolated in Australia and New Zealand

Hemagglutination inhibition titers

Excel file with two sheets proving raw HI titer values for representative influenza B virus antigens of Victoria and Yamagata viruses isolated in Australia and New Zealand during 2002–2013 estimated against representative antisera. Strain names and passage history are provided for each antigen and antisera

Cases positive for influenza B viruses

Tab delimited text file providing patient age, country, date of sampling and lineage (Victoria or Yamagata) of 5260 influenza B viruses collected in Australia and New Zealand, 2002–201

Prevalence percentage

Tab delimited text file providing percentages of viruses that were of type B in Australia (aus) and New Zealand (nz) and the three eastern states of Australia, New South Wales (nsw), Queensland (qld) and Victoria (vic). The percentage of viruses that were of Yamagata and Victoria lineages among all influenza B virus positive samples are provided for Australia (aus_yamagata and aus_victoria) and New Zealand (nz_yamagata and nz_victoria)

Phylodynamic analysis

Beast input file (xml) with data and parameters used to estimate epidemiological parameters (the effective reproductive number, Re) for each epidemic of virus lineages in Australia and New Zealand using the Birth-Death susceptible-infected-removed (BDSIR) model

Virus accession numbers

Tab delimited text file for 908 newly generated influenza B virus samples isolated from humans in Australia and New Zealand during 2002–2013. For each of these samples, virus sample name, collection data, country and GenBank or GISAID accession numbers of each gene segment are provided

Phylogeographic analysis

Beast input file (xml) with data and parameters used to estimate counts of migration to and from Australia and New Zealand using the CTMC model