Pengaruh Struktur Modal Terhadap Nilai Perusahaan Pada Perusahaan Manufaktur Go Publik (Studi Kasus Sektor Makanan Dan Minuman)

This study aims to identify and analyze the influence of Capital Structure of the Company Value. The period used in this study was 5 years, from 2010 to 2014. The data used in this research is secondary data, financial highlights (annual report) and performance summary. This study used purposive samplingmethodinorder tocollectthesample. Samples used are the 4 company of Food and Beverages. Analysis of data using simple linear regression analysisAnalysis of data using multiple linear regression analysis with SPSS 19.The results showed that the capital structure simultaneously not significantly affect the Company Value. The results of this study indicate that the variable X no affect variable Y

Analisis Kebutuhan Tenaga Perawat Berdasarkan Beban Kerja dengan Menggunakan Metode Workload Indicator Staff Need (Wisn) dan Work Sampling

The study was conducted in private hospital in the city of Binjai, which has 12 policlinic. Outpatient installation have 2 nurses and often ask for additional nurses from the emergency unit when a patient comes to the same outpatient polyclinic at 3 polyclinic or more. In addition the number of visitors has increased 2.5% in 2011 and 3.1% in 2012 while the number of nurses are fixed. Therefore need to analyze the needs of nurses based on workload to know the needs of nurses. Work Sampling method to determine the USAge patterns of working time and Workload Indicator Staff Need ( WISN ) for the calculation of energy need. The results of work sampling observations indicate that the two nurses had worked well because average 93% productive time. The results of calculations by the method of Workload Indicator staff Need ( WISN ) note the need for nurses is 2 people while the analysis it is necessary to the addition of 1 nurse

Dynamic chromatin accessibility landscape changes following interleukin-1 stimulation

Dynamic modifications of chromatin allow rapid access of the gene regulatory machinery to condensed genomic regions facilitating subsequent gene expression. Inflammatory cytokine stimulation of cells can cause rapid gene expression changes through direct signalling pathway-mediated transcription factor activation and regulatory element binding. Here we used the Assay for Transposase Accessible Chromatin with high-throughput sequencing (ATAC-seq) to assess regions of the genome that are differentially accessible following treatment of cells with interleukin-1 (IL-1). We identified 126,483 open chromatin regions, with 241 regions significantly differentially accessible following stimulation, with 64 and 177 more or less accessible, respectively. These differentially accessible regions predominantly correspond to regions of the genome marked as enhancers. Motif searching identified an overrepresentation of a number of transcription factors, most notably RelA, in the regions becoming more accessible, with analysis of ChIP-seq data confirmed RelA binding to these regions. A significant correlation in differential chromatin accessibility and gene expression was also observed. Functionality in regulating gene expression was confirmed using CRISPR/Cas9 genome-editing to delete regions that became more accessible following stimulation in the genes MMP13, IKBKE and C1QTNF1. These same regions were also accessible for activation using a dCas9-transcriptional activator and showed enhancer activity in a cellular model. Together, these data describe and functionally validate a number of dynamically accessible chromatin regions involved in inflammatory signalling

TINJAUAN TERKAIT BIDANG AKUNTANSI DI SEKTOR PRIVAT DAN SEKTOR PUBLIK

Tinjauan Terkait Bidang Akuntansi di Sektor Privat dan Sektor Publik merupakan book chapter terkait materi kuliah di jurusan akuntansi dengan implementasinya pada sektor privat dan sektor publik. Book chapter ini dapat memberikan tinjauan umum bagaimana Sistem Informasi Akuntansi, Perpajakan, Auditing, dan Akuntansi Keuangan tidak hanya di organisasi swasta tapi juga di pemerintahan. Book chapter ini merupakan tulisan ilmiah terapan yang ditulis oleh mahasiswa dengan bimbingan dosen di UPN Veteran Jakarta yang mana mengacu pada permasalahan di berbagai bidang akuntansi yang terjadi di organisasi dan disusun berdasarkan kaidah penulisan artikel ilmiah

Upside-down but headed in the right direction:Review of the highly versatile Cassiopea xamachana system

The upside-down jellyfish Cassiopea xamachana (Scyphozoa: Rhizostomeae) has been predominantly studied to understand its interaction with the endosymbiotic dinoflagellate algae Symbiodinium. As an easily culturable and tractable cnidarian model, it is an attractive alternative to stony corals to understanding the mechanisms driving establishment and maintenance of symbiosis. Cassiopea is also unique in requiring the symbiont in order to complete its transition to the adult stage, thereby providing an excellent model to understand symbiosis-driven development and evolution. Recently, the Cassiopea research system has gained interest beyond symbiosis in fields related to embryology, climate ecology, behavior, and more. With these developments, resources including genomes, transcriptomes, and laboratory protocols are steadily increasing. This review provides an overview of the broad range of interdisciplinary research that has utilized the Cassiopea model and highlights the advantages of using the model for future research