2 research outputs found
Study of Surface Morphology and Porosity of Composite Scaffold Nanofiber PVA/CS/HA with Electrospinning Method
This research aims to compose nanofibers as a scaffold material in bone tissue engineering in terms of surface morphological properties and porosity. HA nanorod was prepared by the precipitation-ultrasonication method, while the PVA/CS/HA nanofiber composites were made by the electrospinning method using a static collector. HA was characterized by using XRD and SEM-EDX, while the PVA/CS/HA nanofiber composites used FTIR and SEM. The results show that HA nanorod has a crystalline size of 10.86 nm, crystallinity level of 52.38 per cent, and Ca/P ratio of 1.70. From the SEM image shows HA nanorod width of 11.6 nm and 97.53 nm in length and some of it still in the form of HA nanoparticles. The diameter and porosity of PVA/CS/HA nanofiber with addition of 0, 10, 20 per cent HA were 275, 212, 265 nm and 72.94, 69.49, 70.81 per cent, respectively.DOI: 10.17977/um024v6i12021p02
Effect of nano-hydroxyapatite (n-HAp)/PLA scaffold composites on porosity and microstructure
Nowadays, bone tissue engineering is developed rapidly along with better and faster healing needs. One application of bone tissue engineering is improvement in defects. This improvement was completed by regenerating the tissue through a skeleton called scaffold. In this study, nano-Hydroxyapatite (n-HAp)/PLA scaffold composites were successfully made with variations in composition. The basic ingredients for making n-HAp are from natural materials using the sonication method. Addition of PLA into the nHAp matrix was carried out with variations of 10, 20, 30, 40 and 50 wt%. Nano-HAp was characterized using XRD and SEM. n-HAp/PLA composites were characterized by SEM and porosity tests were carried out. The results showed the crystal size of HAp was 14.46nm. The most optimal porosity test on composites with the composition of n-HAp: PLA; 90:10 wt%