77 research outputs found

    Social pedagogy and citizenship education in England: an exploration with case studies involving secondary school students in London

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    This article explores the theoretical underpinning of citizenship education as theorised in the Crick Report and social pedagogy as deployed in England through the Social Pedagogy Professional Association Charter and Standards of Proficiency. The aims of citizenship education in England have several parallels to contemporary concepts of social pedagogy. In the original conception of citizenship education, the subject aimed to educate the student holistically, developing well-rounded, informed young people able to participate fully in public life through the use of democratic practices in the classroom. However, over time and due to policy and practice changes in secondary education, there have been marked differences in the original conception of the subject, compared to how it is currently delivered in some schools. Despite these challenges, this article highlights strong examples of contemporary practice in citizenship education teaching in diverse London secondary schools, highlighting how features of social pedagogy are being deployed. We draw on several aspects of social pedagogy including democratic practice, community engagement, diversity and inclusion, and student agency, illustrating the clear links between citizenship education and social pedagogy in England, as well as outlining some of the key differences

    Community health workers in rural India: analysing the opportunities and challenges Accredited Social Health Activists (ASHAs) face in realising their multiple roles

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    Background: Globally, there is increasing interest in community health worker’s (CHW) performance; however, there are gaps in the evidence with respect to CHWs’ role in community participation and empowerment. Accredited Social Health Activists (ASHAs), whose roles include social activism, are the key cadre in India’s CHW programme which is designed to improve maternal and child health. In a diverse country like India, there is a need to understand how the ASHA programme operates in different underserved Indian contexts, such as rural Manipur. Methods: We undertook qualitative research to explore stakeholders’ perceptions and experiences of the ASHA scheme in strengthening maternal health and uncover the opportunities and challenges ASHAs face in realising their multiple roles in rural Manipur, India. Data was collected through in-depth interviews (n = 18) and focus group discussions (n = 3 FGDs, 18 participants). Participants included ASHAs, key stakeholders and community members. They were purposively sampled based on remoteness of villages and primary health centres to capture diverse and relevant constituencies, as we believed experiences of ASHAs can be shaped by remoteness. Data were analysed using the thematic framework approach. Results: Findings suggested that ASHAs are mostly understood as link workers. ASHA’s ability to address the immediate needs of rural and marginalised communities meant that they were valued as service providers. The programme is perceived to be beneficial as it improves awareness and behaviour change towards maternal care. However, there are a number of challenges; the selection of ASHAs is influenced by power structures and poor community sensitisation of the ASHA programme presents a major risk to success and sustainability. The primary health centres which ASHAs link to are ill-equipped. Thus, ASHAs experience adverse consequences in their ability to inspire trust and credibility in the community. Small and irregular monetary incentives demotivate ASHAs. Finally, ASHAs had limited knowledge about their role as an ‘activist’ and how to realise this. Conclusions: ASHAs are valued for their contribution towards maternal health education and for their ability to provide basic biomedical care, but their role as social activists is much less visible as envisioned in the ASHA operational guideline. Access by ASHAs to fair monetary incentives commensurate with effort coupled with the poor functionality of the health system are critical elements limiting the role of ASHAs both within the health system and within communities in rural Manipur

    Ecto-5′-nucleotidase and intestinal ion secretion by enteropathogenic Escherichia coli

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    Enteropathogenic Escherichia coli (EPEC) triggers a large release of adenosine triphosphate (ATP) from host intestinal cells and the extracellular ATP is broken down to adenosine diphosphate (ADP), AMP, and adenosine. Adenosine is a potent secretagogue in the small and large intestine. We suspected that ecto-5′-nucleotidase (CD73, an intestinal enzyme) was a critical enzyme involved in the conversion of AMP to adenosine and in the pathogenesis of EPEC diarrhea. We developed a nonradioactive method for measuring ecto-5′-nucleotidase in cultured T84 cell monolayers based on the detection of phosphate release from 5′-AMP. EPEC infection triggered a release of ecto-5′-nucleotidase from the cell surface into the supernatant medium. EPEC-induced 5′-nucleotidase release was not correlated with host cell death but instead with activation of phosphatidylinositol-specific phospholipase C (PI-PLC). Ecto-5′-nucleotidase was susceptible to inhibition by zinc acetate and by α,β-methylene-adenosine diphosphate (α,β-methylene-ADP). In the Ussing chamber, these inhibitors could reverse the chloride secretory responses triggered by 5′-AMP. In addition, α,β-methylene-ADP and zinc blocked the ability of 5′-AMP to stimulate EPEC growth under nutrient-limited conditions in vitro. Ecto-5′-nucleotidase appears to be the major enzyme responsible for generation of adenosine from adenine nucleotides in the T84 cell line, and inhibitors of ecto-5′-nucleotidase, such as α,β-methylene-ADP and zinc, might be useful for treatment of the watery diarrhea produced by EPEC infection

    SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

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    Kidney failure is frequently observed during and after COVID-19, but it remains elusive whether this is a direct effect of the virus. Here, we report that SARS-CoV-2 directly infects kidney cells and is associated with increased tubule-interstitial kidney fibrosis in patient autopsy samples. To study direct effects of the virus on the kidney independent of systemic effects of COVID-19, we infected human-induced pluripotent stem-cell-derived kidney organoids with SARS-CoV-2. Single-cell RNA sequencing indicated injury and dedifferentiation of infected cells with activation of profibrotic signaling pathways. Importantly, SARS-CoV-2 infection also led to increased collagen 1 protein expression in organoids. A SARS-CoV-2 protease inhibitor was able to ameliorate the infection of kidney cells by SARS-CoV-2. Our results suggest that SARS-CoV-2 can directly infect kidney cells and induce cell injury with subsequent fibrosis. These data could explain both acute kidney injury in COVID-19 patients and the development of chronic kidney disease in long COVID

    Paleontology of leaf beetles

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    `The rate of evolution in any large group is not uniform; there are periods of relatise stability, and periods of comparatively rapid change.' Cockerell and LeVeque, 1931 To Yenli Ych, my beloved wife, a most wonderful person! The fossil record of the Chrysomelidae can be tentatively traced back to the late Paleozoic to early Mesozoic Triassic. Mesozoic records at least 9 subfamilies, 19 genera, and 35 species, are represented by the Sagrinae, the exclusively Mesozoic Proto scelinae, Clytrinae, Cryptocephalinae, Eumolpinae, Chrysomelinae. Galerucinac, Alticinae, and Cassidinae. Cenozoic records at least 12 subfamilies- 63 % of the extant- 12! genera, and 325 species, include the same extant subfamilies as well as the Donaciinae, Zeugophorinae, Criocerinae, and Hispinae and can be frequently identified to genus, especially if preserved in amber. Quaternary records are often identified to extant species. tn total, at least t3! genera about 4 % of total extant, and 357 species < 1 % have been reported. At least, 24 genera <1 % of the extant seem to be extinct. Although reliable biological information associated with the fossil chrysomelids is very scarce, it seems that most of the modern host-plant associations were established, at least, in the late Mesozoic to early Cenozoic. As a whole, stasis seems to be the general rule of the chrysomelid fossil record. Together with other faunal elements, chrysomelids, especially donaciines, have been used as biogeographic and paleoclimatological indicators in the Holocene. I

    Predictive relationship between motivation and perceived career choice among undergraduate students in Ghana

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    The study investigated the predictive relationship between motivation and perceived career choice among undergraduate, professional, and Diploma students from the University of Professional Studies, Accra. Descriptive correlational research design was used to investigate the relationships among motivation (e.g., intrinsic and extrinsic) and perceived career choice. Using reliable questionnaire, data were collected from 170 respondents. The hypothesized relationships were tested using Pearson correlation and hierarchical multiple regression test. The result showed that motivation significantly and positively predicted perceived career choice, and accounted for 8.9 percent of the variance in perceived career choice. In addition, intrinsic and extrinsic motivation significantly and positively predicted perceived career choice with intrinsic motivation accounting for more variance in perceived career choice (6.5%) than extrinsic motivation (1.9%). The findings were consistent with Herzberg Two-Factor and expectancy theories of motivation. The implications and limitations of the study have been discussed.Keywords: motivation, perceived career choice, students, Ghan

    An Assessment Of Service Quality In Three Banks Operating In Ghana

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    An assessment of the service quality of three banks operating in Ghana has been undertaken to establish the relationship between service quality and level of customer satisfaction in the banking industry in Ghana. The methodology was based on a cross sectional study of three hundred bank customers selected from three different banks with a self-developed study instrument and a weighting system adapted from William L Boyd, Myron Leonard and Charles White\'s Standard Instrument for weighting of rating of service quality attributes. The results indicated a direct link between service quality variables and customer satisfaction in the banking industry, and supported observed trends in banking award scheme over the past five years.Journal of Business Research Vol. 1 (1&2) 2007: pp. 7-2
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