Acute hemorrhagic leukoencephalitis a rare presentation of dengue fever: a case report

Dengue virus infection is widespread in the tropics and infection ranges from asymptomatic to dengue fever, dengue hemorrhagic fever and dengue shock syndrome. It rarely leads to neurological complications because it is classically a non-neurotropic virus. Encephalitis, meningitis, encephalopathy, acute disseminated encephalomyelitis (ADEM), polyneuropathy, mononeuropathy, intracerebral hemorrhage and Guillain-Barre syndrome are very rare neurological manifestations seen in dengue. The list of neurological complications should also include “Dengue hemorrhagic leukoencephalitis is a very rare manifestation of this virus. Here we present a case of a 23 year old male having dengue fever and developing acute hemorrhagic leukoencephalitis during the course of the disease.Keywords: Dengue fever, acute hemorrhagic leukoencephalitis, meningiti

Scale-up of cell culture processes using Digital Twins

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MODELING AND OPTIMIZATION OF BIODIESEL REACTOR AND FEEDSTOCK

Ph.DDOCTOR OF PHILOSOPHY (FOE

Hypereosinophilic syndrome mimicking acute coronary syndrome

Hypereosinophilic syndrome (HES) is a heterogeneous group of disorders with peripheral blood hypereosinophilia and eosinophil-mediated organ involvement. It may be primary, secondary, or idiopathic. In very rare cases, HES can be familial occurring as an autosomal dominant disorder. Cardiac involvement usually presents as heart failure, intracardiac thrombus, arrhythmias, and rarely as acute coronary syndrome (ACS) and is a major cause of morbidity and mortality. Cardiac magnetic resonance imaging has emerged as a diagnostic modality in diagnosis of eosinophilic endomyocardial disease. We report a case of a young male with familial HES presenting as ACS and discuss diagnostic and therapeutic clinical management

Automated achromatic perimetry

Visual field (VF) testing is an important diagnostic tool for Glaucoma. The current gold standard for VF testing is automated perimetry. This article is an attempt to familiarize the reader with components of an achromatic (white on white) automated perimetry printout. It addresses use of Humphrey perimeter to interpret the results. For the purpose of this review, a PubMed search was made using perimetry, Humphrey VFs review as key words and the relevant articles were studied. The references appended with these articles were also analyzed, and any appropriate article was also included. A systematic approach has been outlined that results in a thorough interpretation of the printout. One should be able to identify a normal field and establish glaucomatous progression, detect the presence of a field defect, determine whether it is due to glaucoma or neuro-ophthalmic disease if any. Comprehensive evaluation using clinical examination, tonometry, and perimetry should be considered together to make a proper diagnosis of glaucoma and judge its progression over time

A novel methodology for the design of waste heat recovery network in eco-industrial park using techno-economic analysis and multi-objective optimization

Based on share of energy, materials, resources and information, Eco Industrial Park (EIP) has become a popular form of industry cluster. Waste Heat Recovery (WHR) in EIP can significantly increase the total energy efficiency of the whole park, meanwhile reducing its greenhouse gas emission. The current paper proposes a methodology to assess the opportunities of WHR in EIP at park level. Four different steps are included in this methodology. The first step is identification of waste heat source plants and sink plants in EIP; the second step is the establishment of the waste heat transportation system; the third step is a Single-Objective Optimization Problem (SOOP); the fourth step is Multi-Objective Optimization Problem (MOOP). An EIP on Jurong Island Singapore comprising of five plants and two communities is used as a case study to demonstrate the capability of this methodology. Two different operation modes for the EIP are considered: with continuous waste heat and with discontinuous waste heat over time. The first scenario shows that SOOP and MOOP will deliver different WHR networks; the second scenario shows that waste heat discontinuity has great influence on the optimization of the WHR network. \ua9 201