Investigating a simple model of cutaneous wound healing angiogenesis

A simple model of wound healing angiogenesis is presented, and investigated using numerical and asymptotic techniques. The model captures many key qualitative features of the wound healing angiogenic response, such as the propagation of a structural unit into the wound centre. A detailed perturbative study is pursued, and is shown to capture all features of the model. This enables one to show that the level of the angiogenic response predicted by the model is governed to a good approximation by a small number of parameter groupings. Further investigation leads to predictions concerning how one should select between potential optimal means of stimulating cell proliferation in order to increase the level of the angiogenic response

A re-description of Frillagalma vityazi Daniel 1966 (Siphonophorae, Agalmatidae)

Ten complete specimens of Frillagalma vityazi Daniel, 1966 (Siphonophorae, Agalmatidae) were collected by the submersibles Johnson-Sea-Link I and II. These have allowed a more detailed description of the species to be made, as it was previously known only by its ill-preserved nectophores and one type of its bracts. The taxonomic status of the species is discussed. In addition much material has been identified from the Discovery collections, and the distribution of the species in the North Atlantic Ocean is considered.No disponibl

Generation of internal stress and its effects

Internal stresses may be generated continually in many polycrystalline materials. Their existence is manifested by changes in crystal defect concentration and arrangement, by surface observations, by macroscopic shape changes and particularly by alteration of mechanical properties when external stresses are simultaneously imposed

Two-dimensional superharmonic stability of finite-amplitude waves in plane Poiseuille flow

In recent work on shear-flow instability, the tacit assumption has been made that the two-dimensional stability of finite-amplitudes waves in plane Poiseuille flow follows a simple and well-understood pattern, namely one with a stability transition at the limit point in Reynolds number. Using numerical stability calculations we show that the application of heuristic arguments in support of this assumption has been in error, and that a much richer picture of bifurcations to quasi-periodic flows can arise from considering the two-dimensional superharmonic stability of such a shear flow

Life Expectancy: Social Work with Centenarians

Although the older population as a whole is increasing faster than any other age group, the most dramatic growth is in the oldest old. Centenarians, those individuals who have survived 100 or more years, have increased ten times in size over the past forty years. This population trajectory is expected to accelerate even more into the next century. Unfomately, social work with the older population rarely includes practice issues related to work with these older adults who have survived well past the average lie expectancy. This article provides a description of the current cohort of centenarians from a biopsychosocial framework and presents an agenda for social work practice, policy and research

The Children and Young People’s Improving Access to Psychological Therapies (CYP IAPT) Programme in England

The Children and Young People's Improving Access to Psychological Therapies (CYP IAPT) programme was initiated in 2011 by the Department of Health. It aimed to improve the access of children, young people and their families to evidence-based psychological therapies (EBPTs) and to seek their participation in all aspects of care, service delivery and design. CYP IAPT addresses the broad range of mental health difficulties commonly presenting to community-based child and adolescent mental health services (CAMHS). The programme took advantage of pre-existing CAMHS partnerships between public commissioners of mental health services and the NHS, local authorities and the charity and voluntary sector service providers. In CYP IAPT, mandatory routine outcome monitoring (ROM) measures of user participation typically take the form of standardized questionnaires used before each treatment session to gauge the severity of the patient's problems, their sense of progress towards their goals, and the extent to which their expectations of treatment were met

Chiral Reductions in the Salam-Sezgin Model

Reductions from six to four spacetime dimensions are considered for a class of supergravity models based on the six-dimensional Salam-Sezgin model, which is a chiral theory with a gauged U(1) R-symmetry and a positive scalar-field potential. Reduction on a sphere and monopole background of such models naturally yields four-dimensional theories without a cosmological constant. The question of chirality preservation in such a reduction has been a topic of debate. In this article, it is shown that the possibilities of dimensional reduction bifurcate into two separate consistent dimensional-reduction schemes. One of these retains the massless SU(2) vector gauge triplet arising from the sphere's isometries, but it produces a non-chiral four-dimensional theory. The other consistent scheme sets to zero the SU(2) gauge fields, but retains the gauged U(1) from six dimensions and preserves chirality although the U(1) is spontaneously broken. Extensions of the Salam-Sezgin model to include larger gauge symmetries produce genuinely chiral models with unbroken gauge symmetries.Comment: 37 page