4,496 research outputs found
Constitutive Equations for Use in Design Analyses of Long-life Elevated Temperature Components
Design analysis needs and procedures relative to elevated temperature components in liquid metal fast breeder reactor (LMFBR) system were examined. The effects of the thermal transients on the pressure boundary components are enhanced by the excellent heat transfer properties of the liquid sodium coolant. Design criteria for high temperature nuclear reactor components recognize the potential occurrence of inelastic structural response. Specifically, criteria and limits were developed which reflect a recognition of this potential and employ design by analysis concepts that requires that inelastic (elastic-plastic and creep) analyses be performed. Constitutive equations to represent multiaxial time-dependent responses of LMFBR alloys are established. The development of equations applicable under cyclic loading conditions are outlined
Feeding difficulties in young children with and without autism.
Although not a criteria for diagnosis of autism, feeding difficulties are commonly found in this population. The purpose of this thesis is to provide further insight in the area of autism and feeding. Parents of children with and without autism were recruited from the Weisskopf Child Evaluation Center and from their home. Participants were asked to complete a series of questionnaires regarding their child\u27s eating habits. Results found parents of both groups indicated their child exhibits oral sensory processing differences, with the autism group indicating additional sensory differences across a range of categories. Results also found parents expressed concerns for their child\u27s eating habits and appeared interested in seeking feeding therapy at some point in the future. Research in the area of autism and feeding is limited, although the prevalence of feeding difficulties in this population is high. This study was the first to compare feeding difficulties of children with autism to typically developing children with feeding problems. Further study in this area is imperative to help clinicians better understand and develop the most appropriate intervention for pediatric feeding difficulties
The Perceptions and Attitudes of Hispanics toward Law Enforcement Officers
Relationships between racial / ethnic minorities and law enforcement officers in the United States have long been a topic of concern. Given that Hispanics represent the largest racial / ethnic minority population in the United States, the nature of their collective and individual relationships with law enforcement is a topic worthy of empirical examination. Surprisingly, however, there is limited research specifically focusing upon the beliefs, perceptions and attitudes of Hispanics regarding law enforcement officers. This exploratory study examines the beliefs, perceptions, and attitudes of 101 Hispanics in South central Mississippi toward local law enforcement agencies and officers. Furthermore, the study examines the willingness of Hispanics to report various forms of crime. The findings of this study indicate that respondents manifested generally positive beliefs, perceptions and attitudes regarding law enforcement officers and indicated a willingness to report serious crimes. The study also indicates that more work needs to be done to enhance the relationship between members of the Hispanic immigrant community and law enforcement officers and agencies. The study also indicates a need for further empirical exploration of the topic and advanced methods of statistical analysis
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In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury.
Microglia respond to damage and microenvironmental changes within the central nervous system by morphologically transforming and migrating to the lesion, but the real-time behavior of populations of these resident immune cells and the neurons they support have seldom been observed simultaneously. Here, we have used in vivo high-resolution optical coherence tomography (OCT) and scanning laser ophthalmoscopy with and without adaptive optics to quantify the 3D distribution and dynamics of microglia in the living retina before and after local damage to photoreceptors. Following photoreceptor injury, microglia migrated both laterally and vertically through the retina over many hours, forming a tight cluster within the area of visible damage that resolved over 2 wk. In vivo OCT optophysiological assessment revealed that the photoreceptors occupying the damaged region lost all light-driven signaling during the period of microglia recruitment. Remarkably, photoreceptors recovered function to near-baseline levels after the microglia had departed the injury locus. These results demonstrate the spatiotemporal dynamics of microglia engagement and restoration of neuronal function during tissue remodeling and highlight the need for mechanistic studies that consider the temporal and structural dynamics of neuron-microglia interactions in vivo
The Legacy of Olaf Sparre Andersen and Future Directions of the Journal of General Physiology
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