280 research outputs found

    Fat gain with physical detraining is correlated with increased glucose transport and oxidation in periepididymal white adipose tissue in rats

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    As it is a common observation that obesity tends to occur after discontinuation of exercise, we investigated how white adipocytes isolated from the periepididymal fat of animals with interrupted physical training transport and oxidize glucose, and whether these adaptations support the weight regain seen after 4 weeks of physical detraining. Male Wistar rats (45 days old, weighing 200 g) were divided into two groups (n=10): group D (detrained), trained for 8 weeks and detrained for 4 weeks; and group S (sedentary). The physical exercise was carried out on a treadmill for 60 min/day, 5 days/week for 8 weeks, at 50-60% of the maximum running capacity. After the training protocol, adipocytes isolated from the periepididymal adipose tissue were submitted to glucose uptake and oxidation tests. Adipocytes from detrained animals increased their glucose uptake capacity by 18.5% compared with those from sedentary animals (P<0.05). The same cells also showed a greater glucose oxidation capacity in response to insulin stimulation (34.55%) compared with those from the S group (P<0.05). We hypothesize that, owing to the more intense glucose entrance into adipose cells from detrained rats, more substrate became available for triacylglycerol synthesis. Furthermore, this increased glucose oxidation rate allowed an increase in energy supply for triacylglycerol synthesis. Thus, physical detraining might play a role as a possible obesogenic factor for increasing glucose uptake and oxidation by adipocytes487650653CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPsem informação2006/60403-

    Particules d’aspect viral dans les cellules du lymphosarcome du chien

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    Dans le tissu ganglionnaire de deux chiens atteints de lymphosarcome, il a été trouvé des particules rappelant les virus des leucémies murines

    Cobalt ferrite thin films deposited by electrophoresis on p-doped Si substrates

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    The structural and magnetic properties of cobalt ferrite (CoFe2O4) thin films deposited by electrophoresis on p-doped Si(001) substrates have been characterized. The films were polycrystalline and composed by cobalt ferrite with the cubic spinnel structure. The observed decrease of the coercive field with the sixth power of the grain size was indicative of a competition between the magnetocrystalline anisotropy and the exchange coupling energy, on these randomly oriented nanosized grained films.J. Barbosa and M.P. Proenca gratefully acknowledge a PhD grant from Fundacao para a Ciencia e Tecnologia (SFRH/BD/41913/2007 and SFRH/BD/43440/2008, respectively)

    The role of Cu length on the magnetic behaviour of Fe/Cu multi-segmented nanowires

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    CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOA set of multi-segmented Fe/Cu nanowires were synthesized by a two-step anodization process of aluminum substrates and a pulsed electrodeposition technique using a single bath. While both Fe segment length and diameter were kept constant to (30 +/- 7) and (45 +/- 5) nm, respectively, Cu length was varied between (15 +/- 5) and (120 +/- 10) nm. The influence of the non-magnetic layer thickness variation on the nanowire magnetic properties was investigated through first-order reversal curve (FORC) measurements and micromagnetic simulations. Our analysis confirmed that, in the multi-segmented Fe/Cu nanowires with shorter Cu segments, the dipolar coupling between Fe segments controls the nanowire magnetic behavior, and its performance is like that of a homogenous Fe nanowire array of similar dimensions. On the other hand, multi-segmented Fe/Cu nanowires with larger Cu segments act like a collection of non-interacting magnetic entities (along the nanowire axis), and their global behavior is mainly controlled by the neighbor-to-neighbor nanodisc dipolar interactions.87112CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO234513/2014-4sem informaçãoAgências de fomento estrangeiras apoiaram essa pesquisa, mais informações acesse artig

    Qualifying instrument for evaluation of food and nutritional care in hospital

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    Establishing criteria for hospital nutrition care ensures that quality care is delivered to patients. The responsibility of the Hospital Food and Nutrition Service (HFNS) is not always well defined, despite efforts to establish guidelines for patient clinical nutrition practice. This study describes the elaboration of an Instrument for Evaluation of Food and Nutritional Care (IEFNC) aimed at directing the actions of the Hospital Food and Nutrition Service. This instrument was qualified by means of a comparative analysis of the categories related to hospital food and nutritional care, published in the literature. Elaboration of the IEFNC comprised the following stages: (a) a survey of databases and documents for selection of the categories to be used in nutrition care evaluation, (b) a study of the institutional procedures for nutrition practice at two Brazilian hospitals, in order to provide a description of the sequence of actions that should be taken by the HFNS as well as other services participating in nutrition care, (c) design of the IEFNC based on the categories published in the literature, adapted to the sequence of actions observed in the routines of the hospitals under study, (d) application of the questionnaire at two different hospitals that was mentioned in the item (b), in order to assess the time spent on its application, the difficulties in phrasing the questions, and the coverage of the instrument, and (e) finalization of the instrument. The IEFNC consists of 50 open and closed questions on two areas of food and nutritional care in hospital: inpatient nutritional care and food service quality. It deals with the characterization and structure of hospitals and their HFNS, the actions concerning the patients' nutritional evaluation and monitoring, the meal production system, and the hospital diets. "This questionnaire is a tool that can be seen as a portrait of the structure and characteristics of the HFNS and its performance in clinical and meal management dietitian activities." (Nutr Hosp. 2012;27:1170-1177) DOI:10.3305/nh.2012.27.4.5868FAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP

    Predictive biometrics: A review and analysis of predicting personal characteristics from biometric data

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    Interest in the exploitation of soft biometrics information has continued to develop over the last decade or so. In comparison with traditional biometrics, which focuses principally on person identification, the idea of soft biometrics processing is to study the utilisation of more general information regarding a system user, which is not necessarily unique. There are increasing indications that this type of data will have great value in providing complementary information for user authentication. However, the authors have also seen a growing interest in broadening the predictive capabilities of biometric data, encompassing both easily definable characteristics such as subject age and, most recently, `higher level' characteristics such as emotional or mental states. This study will present a selective review of the predictive capabilities, in the widest sense, of biometric data processing, providing an analysis of the key issues still adequately to be addressed if this concept of predictive biometrics is to be fully exploited in the future

    Experimental evaluation of a passive flow-control device for a tiltrotor aircraft

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    This work presents a preliminary investigation into tiltrotor propeller/nacelle/wing flows, and the flow breakdowns that can lead to the phenomenon of whirl flutter. Static blade measurements were performed, results suggesting that tubercles have the potential to provide an increase in performance for the baseline blade design. A small-scale propeller rig (0.7 m swept diameter) has been designed, manufactured, and commissioned at Cranfield’s 8x6 Wind Tunnel. This new rig operates well under static and up to wind speeds of at least 30 m/s. The effect of blade pitch angle (0 to 10◦ ) and propeller rotational speed (0 to 3000 rpm) have been investigated successfully. Forces measured on the wing set at angles of attack within the range 0 to 22◦ indicate the well-established effects due to propeller slipstream. Overall, the propeller wake flow slightly decreases the lift generated by the wing model, whilst also delaying stall. Pressure taps and accelerometers mounted on the wing and propeller nacelle effectively captured the slipstream effects, blade passing frequency, and flow separation regions. Finally, blades containing tubercle-shaped vortex generators were mounted to the propeller rig. Preliminary test results for the tubercle blades are reported in the paper. Overall, effects due to the propeller slipstream are dominant on forces, pressure distribution and vibration of the wing model. At the current stage of this ongoing investigation, it is not possible to conclude whether the tubercles provide any benefit to either the propeller or wing aerodynamic efficiencies. The rig is being equipped to measure propeller thrust and torque. Flow field investigation will also be carried out in future campaigns

    Hypertrophic Adenoid Is A Major Infection Site Of Human Bocavirus 1.

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    Human bocavirus 1 (HBoV1) is associated with respiratory infections worldwide, mainly in children. Similar to other parvoviruses, it is believed that HBoV1 can persist for long periods of time in humans, probably through maintaining concatemers of the virus single-stranded DNA genome in the nuclei of infected cells. Recently, HBoV-1 was detected in high rates in adenoid and palatine tonsils samples from patients with chronic adenotonsillar diseases, but nothing is known about the virus replication levels in those tissues. A 3-year prospective hospital-based study was conducted to detect and quantify HBoV1 DNA and mRNAs in samples of the adenoids (AD), palatine tonsils (PT), nasopharyngeal secretions (NPS), and peripheral blood (PB) from patients undergoing tonsillectomy for tonsillar hypertrophy or recurrent tonsillitis. HBoV1 was detected in 25.3% of the AD samples, while the rates of detection in the PT, NPS, and PB samples were 7.2%, 10.5%, and 1.7%, respectively. The viral loads were higher in AD samples, and 27.3% of the patients with HBoV had mRNA detectable in this tissue. High viral loads and detectable mRNA in the AD were associated with HBoV1 detection in the other sample sites. The adenoids are an important site of HBoV1 replication and persistence in children with tonsillar hypertrophy. The adenoids contain high HBoV1 loads and are frequently positive for HBoV mRNA, and this is associated with the detection of HBoV1 in secretions.523030-

    Combination antiretroviral therapy and the risk of myocardial infarction

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    Psidium spp.: araçá.

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