Hybrid modeling and optimization of biological processes

Proß S. Hybrid modeling and optimization of biological processes. Bielefeld: Bielefeld University; 2013

An Advanced Environment for Hybrid Modeling of Biological Systems Based on Modelica

Biological systems are often very complex so that an appropriate formalism is needed for modeling their behavior. Hybrid Petri Nets, consisting of time-discrete Petri Net elements as well as continuous ones, have proven to be ideal for this task. Therefore, a new Petri Net library was implemented based on the object-oriented modeling language Modelica which allows the modeling of discrete, stochastic and continuous Petri Net elements by differential, algebraic and discrete equations. An appropriate Modelica-tool performs the hybrid simulation with discrete events and the solution of continuous differential equations. A special sub-library contains so-called wrappers for specific reactions to simplify the modeling process

A New Object-Oriented Petri Net Simulation Environment Based On Modelica

Proß S, Bachmann B, Janowski SJ, Hofestädt R. A New Object-Oriented Petri Net Simulation Environment Based On Modelica. In: Laroque C, ed. Proceedings of the 2012 Winter Simulation Conference (WSC). Piscataway, NJ: IEEE; 2012: 1-13

Modelling a Bacteriums's Life: A Petri-Net Library in Modelica

Proß S, Bachmann B, Hofestädt R, et al. Modelling a Bacteriums's Life: A Petri-Net Library in Modelica. In: Casella F, ed. Linköping Electronic Conference Proceedings. Linköping University Electronic Press; 2009: 463-472