Effect of Arginine and Citrulline Supplements on Cardiovascular Health and Sports Activities: A Narrative Review on Indian Perspective

The use of nutritional supplements (NS) for improving sports performance and health has become popular, and Citrulline and Arginine are the most frequently used supplements in these fields. The global market for dietary supplements has had consistent growth in sales in the last decades. More than half of the individuals use dietary supplement extensively. Present systematic review aims to understand the role of dietary arginine and Citrulline supplements for cardiovascular health and sports performance. The complicated connection between the control of hemodynamic and overall homeostasis and Citrulline and Arginine have been established. Citrulline and Arginine play important role in protecting skeletal as well as health of cardiac muscles and structural integrity and also are involved in many metabolic processes. Arginine has successfully mediated the release of the synthesis of creatinine growth hormone, which significantly increases strength and muscle mass. Also, Arginine is necessary to produce nitric oxide, which promotes skeletal muscle growth and also enhances vascular function. Overall, arginine supplements have a reasonable positive effect on the health of the heart, muscles and bones, as well as on maintaining and escalate exercise capacity. On the other hand, Citrulline can possibly converted into Arginine in many cell types and can effectively make up shortages of Arginine and nitric oxide in various pathological and physiological circumstances. Moreover, Citrulline helps to detoxify ammonia while decreasing stress levels and fatigue and promoting performance of exercise. In order to increase and enhance human athletic activities, both arginine and Citrulline are require

Oral manifestations of illicit drug use

Oral health problems, among the most prevalent comorbidities related to addiction, require more attention by both clinicians and policy-makers. Our aims were to review oral complications associated with drugs, oral health care in addiction rehabilitation, health services available, and barriers against oral health promotion among addicts. Drug abuse is associated with serious oral health problems including generalized dental caries, periodontal diseases, mucosal dysplasia, xerostomia, bruxism, tooth wear, and tooth loss. Oral health care has positive effects in recovery from drug abuse: patients’ need for pain control, destigmatization, and human immune-deficiency virus (HIV) transmission. Health care systems worldwide deliver services for addicts, but most lack oral health care programs. Barriers against oral health promotion among addicts include difficulty in accessing addicts as a target population, lack of appropriate settings and of valid assessment protocols for conducting oral health studies, and poor collaboration between dental and general health care sectors serving addicts. These interfere with an accurate picture of the situation. Moreover, lack of appropriate policies to improve access to dental services, lack of comprehensive knowledge of and interest among dental professionals in treating addicts, and low demand for non-emergency dental care affect provision of effective interventions. Management of drug addiction as a multi-organ disease requires a multidisciplinary approach. Health care programs usually lack oral health care elements. Published evidence on oral complications related to addiction emphasizes that regardless of these barriers, oral health care at various levels including education, prevention, and treatment should be integrated into general care services for addicts

Effects of photo biomodulation on peri-implantitis

Periodontitis is a prevalent infectious disease in which the accumulation of bacterial plaque leads to an inflammatory reaction and destruction of supporting tissues around the teeth. The optimal goal in periodontal treatment is to eliminate the infection and to recreate the lost structures of cementum, periodontal ligament (PDL), and the alveolar bone with the reestablishment of their functions. Achieving this regenerative aim, however, remains a major challenge for periodontists. In order to increase the predictability and the efficacy of regenerative periodontal therapies, treatment modalities have moved from the conventional guided tissue treatments to novel tissue engineering and stem cell–based treatments. This is achieved either by transplantation of cells from outside sources to the periodontal defects or by enhancing the recruitment of endogenous host cells present in the area, known as cell homing methods. Photobiomodulation (PBM) therapy is a term used for exposure of cells/ tissues to low-level laser light or light-emitting diodes (LEDs), which is absorbed by specific photoreceptors in cells and may cause alteration at a molecular level inside cells without any heat generation leading to biological changes in cell metabolism and function.

Palynostratigraphy and palynofacies of the early Eocene Gurha lignite mine, Rajasthan, India

A 105 m early Eocene section exposed in the Gurha mine in the Nagaur-Ganganagar Basin, Rajasthan, India, archiving remains of equatorial vegetation at a time of extreme global warmth and close to the onset of the India-Eurasia collision, is investigated using palynostratigraphic and palynofacies analyses. Four palynozones e.g., Palmidites plicatus Singh, Botryococcus braunii Kützing, Triangulorites bellus Kar and Ovoidites ligneolus are identified stratigraphically on the basis of abundance of these pollen taxa over others. The occurrence of taxonomically highly diverse angiosperm pollen in all the four palynozones attests to an extremely rich near-coastal tropical flora subject to frequent wildfires under a strongly seasonal precipitation regime. Palynotaxa characteristic of these palynozones are widely distributed in other early Paleogene sediments of India. Sedimentary organic matter (structured terrestrial, biodegraded, amorphous, grey amorphous, resins, charcoal/black-brown debris and algal remains) recovered from mire and lacustrine sediments are of terrestrial origin, recording fluctuations in burial anoxia and salinity. Episodes of elevated salinity are due either to seepage of marine waters and/or a periodic excess of evaporation over precipitation at times when the depositional system was closed

Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum