Phenolic cutter for machining foam insulation

Pre-pregged fiber glass is an efficient abrasive for machining polystyrene and polyurethane foams. It bonds easily to any cutter base made of aluminum, steel, or phenolic, is inexpensive, and is readily available

A retrospective study of the prevalence of the canine degenerative myelopathy associated superoxide dismutase 1 mutation (SOD1: c. 118G> A) in a referral population of German Shepherd dogs from the UK

BACKGROUND: Canine degenerative myelopathy (CDM) is an adult onset, progressive neurodegenerative disease of the spinal cord. The disease was originally described in the German Shepherd dog (GSD), but it is now known to occur in many other dog breeds. A previous study has identified a mutation in the superoxide dismutase 1 gene (SOD1:c.118G > A) that is associated with susceptibility to CDM. In the present study, restriction fragment length polymorphism (RFLP) analysis was used to genotype GSD for SOD1:c.118G > A in order to estimate the prevalence of the mutation in a referral population of GSD in the UK. RESULTS: This study demonstrated that the RFLP assay, based on use of PCR and subsequent digestion with the Eco571 enzyme, provided a simple genotyping test for the SOD1:c.118G > A mutation. In a young GSD population (i.e. dogs less than 6 years of age, before clinical signs of the disease usually become apparent), 8 of 50 dogs were found to be homozygous and a further 19 were heterozygous for the mutation. In dogs over 8 years of age, 21 of 50 dogs admitted to a tertiary referral hospital with pelvic limb ataxia as a major clinical sign were homozygous for the mutation, compared to none of 50 dogs of similar age, but where no neurological disease was reported on referral. CONCLUSIONS: This data suggests that genotyping for the SOD1:c.118G > A mutation is clinically applicable and that the mutation has a high degree of penetrance. Genotyping might also be useful for screening the GSD population to avoid mating of two carriers, but since the allele frequency is relatively high in the UK population of GSD, care should be taken to avoid reduction in genetic diversity within the breed

Giant Fluctuations of Coulomb Drag in a Bilayer System

We have observed reproducible fluctuations of the Coulomb drag, both as a function of magnetic field and electron concentration, which are a manifestation of quantum interference of electrons in the layers. At low temperatures the fluctuations exceed the average drag, giving rise to random changes of the sign of the drag. The fluctuations are found to be much larger than previously expected, and we propose a model which explains their enhancement by considering fluctuations of local electron properties.Comment: 10 pages, 4 figure

Piloted simulation of an algorithm for onboard control of time-optimal intercept

A piloted simulation of algorithms for onboard computation of trajectories for time-optimal intercept of a moving target by an F-8 aircraft is described. The algorithms, use singular perturbation techniques, generate commands in the cockpit. By centering the horizontal and vertical needles, the pilot flies an approximation to a time-optimal intercept trajectory. Example simulations are shown and statistical data on the pilot's performance when presented with different display and computation modes are described

Coulomb drag as a measure of trigonal warping in doped graphene

I suggest to use the effect of Coulomb drag between two closely positioned graphite monolayers (graphene sheets) for experimental measurement of the strength of weak non-linearities of the spectrum in graphene. I consider trigonal warping as a representative mechanism responsible for the drag effect. Since graphene is relatively defect-free, I evaluate the drag conductivity in the ballistic regime and find that it is proportional to the fourth power of the warping strength.Comment: 4 pages, 1 figur

Space station full-scale docking/berthing mechanisms development

One of the most critical operational functions for the space station is the orbital docking between the station and the STS orbiter. The program to design, fabricate, and test docking/berthing mechanisms for the space station is described. The design reflects space station overall requirements and consists of two mating docking mechanism halves. One half is designed for use on the shuttle orbiter and incorporates capture and energy attenuation systems using computer controlled electromechanical actuators and/or attenuators. The mating half incorporates a flexible feature to allow two degrees of freedom at the module-to-module interface of the space station pressurized habitat volumes. The design concepts developed for the prototype units may be used for the first space station flight hardware

Gravity gradient attitude control system Patent

Gravity gradient attitude control system with gravity gradiometer and reaction wheels for artificial satellite attitude contro

Van der Waals Frictional Drag induced by Liquid Flow in Low- Dimensional Systems

We study the van der Waals frictional drag force induced by liquid flow in low-dimensional systems (2D and 1D electron systems, and 2D and 1D channels with liquid). We find that for both 1D and 2D systems, the frictional drag force induced by liquid flow may be several orders of magnitude larger than the frictional drag induced by electronic current.Comment: 10 pages, 4 figure