Investigation of the current status of anticoagulant resistance in UK Norway rats by VKORC1 genotyping

Clarke, D.J., Prescott, C.V

Understanding Noncompetition Agreements: The 2014 Noncompete Survey Project

In recent years, scholars and policymakers have devoted considerable attention to the potential consequences of employment noncompetition agreements and to whether legislatures ought to reform the laws that govern the enforcement of these controversial contractual provisions. Unfortunately, much of this interest—and the content of proposed reforms—derives from anecdotal tales of burdensome noncompetes among low-wage workers and from scholarship that is either limited to slivers of the population (across all studies, less than 1%) or relies on strong assumptions about the incidence of noncompetition agreements. Better understanding of the use of noncompetes and effective noncompetition law reform requires a more complete picture of the frequency and distribution of noncompetes at the individual employee level. Accordingly, in 2014, we administered a nationwide survey of individuals in the labor force to ask them about their employment status, history, and future expectations—including their experience with and understanding of noncompetition agreements. In this Article, we describe the methods we used to carry out this survey and refine the data for analysis in hopes of encouraging other researchers to use survey approaches to fill other, similarly important gaps in our knowledge. To illustrate the value of the survey project, we present a surprising empirical finding from our data, one that raises questions about existing scholarship and theories about why employers use noncompetes: We find little evidence that the incidence of noncompetition agreements in a state (after controlling for potentially confounding factors) has any relationship to the level of enforcement of such agreements in that state. In other words, an employee in California (where noncompetes are prohibited) appears to be just as likely to labor under a noncompete as an employee in Florida (where noncompetes are much more likely to be enforced)

The evidence for automated grading in diabetic retinopathy screening

Peer reviewedPostprin

Deep brain stimulation for dystonia

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To compare the efficacy, safety and tolerability of deep brain stimulation versus placebo, sham intervention, or best medical care, including botulinum neurotoxin and resective/lesional surgery, in people with dystonia

Understanding and optimising an identification/brief advice (IBA) service about alcohol in the community pharmacy setting

This is the final report of an evaluation into the identification/brief advice (IBA) service about alcohol in community pharmacy settings in the North West of England. Since 2007, almost 100 pharmacies in the North West have - at some point - been commissioned to provide an identification and brief advice (IBA) service for alcohol. This evaluation sought to understand how the service had been adapted for and implemented in the community pharmacy setting, and how its potential might be maximised. Its aims were: 1. To characterise, consolidate and optimise both the constant and variable elements of the pharmacy alcohol identification/brief advice (IBA) service in NHS Northwest, and 2. To inform planning for current and future pharmacy based services promoting safe consumption of alcohol. The evaluation was split into three main workstreams, supported by a preliminary scoping phase, and combined quantitative and qualitative methods: • Descriptive and comparative statistical analysis of pharmacy alcohol IBA data; • In-pharmacy work, including observation of staff engagement with customers, recording consultations between staff and customers, follow-up telephone interviews with customers, and group feedback interviews with pharmacy staff; • Stakeholder engagement through self-completion surveys, semi-structured interviews and a workshop. This report gives the background to the project, and details the methods, results and implications

Three-Dimensional Thermoluminescence Spectra and Their Application in the Study of Some Sedimentary Quartz

The intensity of thermoluminescence emission is a function of both temperature and photon energy (or wavelength) and therefore lends itself to a three-dimensional (3-D) display, either in the form of an isometric plot or a contour diagram. The technique of 3-D thermoluminescence spectrometry is briefly reviewed and the advantages and applications are illustrated by reference to the spectral properties of samples of Australian sedimentary quartz drawn from the context of thermoluminescence dating. In this context, the temperature of emission, the photon energy and the ease with which the emission is bleachable by sunlight are of significance. It is suggested that, in one of the samples, the energy of the photon emitted from one of the luminescence centres depends on the temperature of emission

Measurement of the parity violating 6S-7S transition amplitude in cesium achieved within 2 \times 10^{-13} atomic-unit accuracy by stimulated-emission detection

We exploit the process of asymmetry amplification by stimulated emission which provides an original method for parity violation (PV) measurements in a highly forbidden atomic transition. The method involves measurements of a chiral, transient, optical gain of a cesium vapor on the 7S-6P_{3/2} transition, probed after it is excited by an intense, linearly polarized, collinear laser, tuned to resonance for one hyperfine line of the forbidden 6S-7S transition in a longitudinal electric field. We report here a 3.5 fold increase, of the one-second-measurement sensitivity, and subsequent reduction by a factor of 3.5 of the statistical accuracy compared with our previous result [J. Gu\'ena et al., Phys. Rev. Lett. 90, 143001 (2003)]. Decisive improvements to the set-up include an increased repetition rate, better extinction of the probe beam at the end of the probe pulse and, for the first time to our knowledge, the following: a polarization-tilt magnifier, quasi-suppression of beam reflections at the cell windows, and a Cs cell with electrically conductive windows. We also present real-time tests of systematic effects, consistency checks on the data, as well as a 1% accurate measurement of the electric field seen by the atoms, from atomic signals. PV measurements performed in seven different vapor cells agree within the statistical error. Our present result is compatible with the more precise Boulder result within our present relative statistical accuracy of 2.6%, corresponding to a 2 \times 10^{-13} atomic-unit uncertainty in E_1^{pv}. Theoretical motivations for further measurements are emphasized and we give a brief overview of a recent proposal that would allow the uncertainty to be reduced to the 0.1% level by creating conditions where asymmetry amplification is much greater.Comment: Article 21 pages, 6 figures, 3 tables Typos, addition of few comments and little more data (1 week) leading to a slight reduction of the error bar Accepted for publication in Phys.Rev.