Elastic stable intramedullary nailing in pediatric diaphyseal forearm bone fracture

Background: Pediatric forearm bone fracture present significant challenges where most of them are managed with closed reduction and casting. Irreducible, unstable and open fracture usually requires operative stabilization. Intramedullary nailing is considered minimal invasive however it is not free of complication. The aim of this study is to analyze the outcome and complications after elastic stable intramedullary nailing in pediatric diaphyseal forearm fracture.Methods: A descriptive observational study was carried out for four years (2013-2016) in diaphyseal pediatric forearm fracture stabilized with titanium elastic stable intramedullary nailing. Final range of motion, complications and outcome were assessed using Clavien-Dindo classification modification appropriate for orthopedic surgery.Results: We report the outcome of 36 patients with complete medical records. Closed reduction and nailing was successful in 25 patients (69.4%) whereas eleven patients (30.6%) required open reduction (both radius and ulna in 6 patients 16.7%, ulna in 3 patients 8.3% and radius in 2 patients 5.6%). Radiological union was achieved at an average of 7.75±1.5 weeks (range 6 to 16 weeks). Forearm rotation was limited in 7 patients with average loss of 16° pronation and 18° supination. The overall rate of complication was 22.2%. According to Clavien-Dindo classification excellent results were noted in 29 patients (80.6%), good in 3 patients (8.3%) and fair in 4 patients (11.1%). Conclusions: Elastic intramedullary nailing in pediatric diaphyseal forearm bones fracture is minimally invasive with low rate of complication and the outcomes are fair to excellent

Analysis of Some Checkpointing Schemes for Distributed Mobile Computing Systems

There exist mobile nodes in a distributed system, which arises some new issues like mobility, disconnections, low bandwidth of wireless channels, limited battery power capacity and lack of reliable stable storage on mobile nodes, that need proper handling when we design a checkpointing algorithm for distributed systems. It is not easy to predict whether the system will prolong to perform throughout or till approved time. Checkpoint is defined as a specify state in a program at which normal process is disrupted typically to maintain the information of status mandatory to allow renewal of processing at a later time in issue of a failure. This paper gives a summary of checkpointing strategies for mobile networks which are categories on the basis of quality of service of wireless networks, based on mobile agents, considering the mobility of MHs and transmission of checkpoints. We also represent a survey of some checkpointing algorithms for distributed systems

Analysis of the clinical profile in patients with Plasmodium falciparum malaria and its association with parasite density

Background: Malaria remains a major health hazard in the modern world, particularly in developing countries. In Plasmodium falciparum malaria, there is a direct correlation between asexual erythrocytic stage parasite density and disease severity. Accordingly, the correlations between parasite density and various clinical presentations, severity, and outcome were examined in falciparum malaria in India. Materials and Methods: The study was conducted in a tertiary health-care center in North India. Of 100 cases of falciparum malaria, 65 patients were male and 35 were female. A total of 54 patients were in the uncomplicated group and 46 patients were in the complicated malaria group. Results: Fever, anemia, icterus, splenomegaly, hepatomegaly, and hepatosplenomegaly were common clinical findings. All clinical findings were significantly more common in the complicated malaria group and patients with a high parasite density than in the uncomplicated group and those with a low parasite density. All patients in the uncomplicated malaria group had a parasite density of 5%, and the difference between groups was statistically significant. The incidence of cerebral malaria was significantly higher in cases with a high parasite density; 58.33% mortality was observed in these cases. Cerebral malaria and hyperbilirubinemia was the most frequently encountered combination of complications. Conclusions: In P. falciparum malaria, parasite density was associated with complications and poor clinical outcomes. These results may inform treatment decisions and suggest that a threshold parasite density of 5% is informative

Hyperdiffusive Dynamics in Newtonian Nanoparticle Fluids

Hyperdiffusive relaxations in soft glassy materials are typically associated with out-of-equilibrium states, and nonequilibrium physics and aging are often invoked in explaining their origins. Here, we report on hyperdiffusive motion in model soft materials comprised of single-component polymer-tethered nanoparticles, which exhibit a readily accessible Newtonian flow regime. In these materials, polymer-mediated interactions lead to strong nanoparticle correlations, hyperdiffusive relaxations, and unusual variations of properties with temperature. We propose that hyperdiffusive relaxations in such materials can arise naturally from nonequilibrium or non-Brownian volume fluctuations forced by equilibrium thermal rearrangements of the particle pair orientations corresponding to equilibrated shear modes

The value of open-source clinical science in pandemic response: lessons from ISARIC

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